Identification of the LEDGF/p75 binding site in HIV-1 integrase (Q24321722)

3

object named as

Marc De Maeyer

0 references

Frauke Christ

9

object named as

Frauke Christ

0 references

author name string

Katrien Busschots

1

0 references

Arnout Voet

2

0 references

Jean-Christophe Rain

4

0 references

Stéphane Emiliani

5

0 references

Richard Benarous

6

0 references

Linda Desender

Journal of Molecular Biology

7

0 references

language of work or name

English

0 references

publication date

2 February 2007

0 references

published in

0 references

volume

365

0 references

issue

5

0 references

page(s)

1480-92

0 references

cites work

Intracellular trafficking of retroviral genomes during the early phase of infection: viral exploitation of cellular pathways

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Antinuclear autoantibodies in prostate cancer: immunity to LEDGF/p75, a survival protein highly expressed in prostate tumors and cleaved during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Lens epithelium-derived growth factor: effects on growth and survival of lens epithelial cells, keratinocytes, and fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

A synthetic peptide bearing the HIV-1 integrase 161-173 amino acid residues mediates active nuclear import and binding to importin alpha: characterization of a functional nuclear localization signal

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Cellular co-factors of HIV-1 integration

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Molecular mechanisms in retrovirus DNA integration

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

HIV-1 infection requires a functional integrase NLS.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

LEDGF/p75: a novel nuclear autoantigen at the crossroads of cell survival and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

The dead-end elimination theorem and its use in protein side-chain positioning

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Comparative architecture of transposase and integrase complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

A role for LEDGF/p75 in targeting HIV DNA integration

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Caspase cleavage of the nuclear autoantigen LEDGF/p75 abrogates its pro-survival function: implications for autoimmunity in atopic disorders

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Transcriptional regulation of the antioxidant protein 2 gene, a thiol-specific antioxidant, by lens epithelium-derived growth factor to protect cells from oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

DNA-induced polymerization of HIV-1 integrase analyzed with fluorescence fluctuation spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

HIV integrase, a brief overview from chemistry to therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Swiss-PDB Viewer (Deep View).

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

An improved PCR-mutagenesis strategy for two-site mutagenesis or sequence swapping between related genes

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Rapid microtiter assays for poxvirus topoisomerase, mammalian type IB topoisomerase and HIV-1 integrase: application to inhibitor isolation

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

High-level expression of active HIV-1 integrase from a synthetic gene in human cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

An essential role for LEDGF/p75 in HIV integration

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Oligomerization within virions and subcellular localization of human immunodeficiency virus type 1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Impact of the central polypurine tract on the kinetics of human immunodeficiency virus type 1 vector transduction

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a postnuclear entry step of human immunodeficiency virus type 1 replication

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Lys-34, dispensable for integrase catalysis, is required for preintegration complex function and human immunodeficiency virus type 1 replication

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Genetic analyses of DNA-binding mutants in the catalytic core domain of human immunodeficiency virus type 1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Intracellular transport of human immunodeficiency virus type 1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021

Human cell proteins and human immunodeficiency virus DNA integration

1 reference

https://api.crossref.org/works/10.1016%2FJ.JMB.2006.10.094

7 January 2021