Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint (Q24324057)

7

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Tiziana Bruno

1

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Monica Di Padova

6

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Francesca De Nicola

2

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Laura Zannini

Laura Zannini

9

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Daniele Lecis

Daniele Lecis

4

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Carlo Leonetti

Carlo Leonetti

15

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Marco Crescenzi

Marco Crescenzi

14

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author name string

Simona Iezzi

3

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Carmen D'Angelo

5

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Leopoldo Dimiziani

8

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Christian Jekimovs

10

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Marco Scarsella

11

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Alessandro Porrello

12

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Alberto Chersi

13

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Kum Kum Khanna

16

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Aristide Floridi

18

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Claudio Passananti

19

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Domenico Delia

20

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Maurizio Fanciulli

Identification of novel transcription factor-like gene from human intestinal cells

21

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language of work or name

English

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publication date

December 2006

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published in

Cancer Cell

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volume

10

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issue

6

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page(s)

473-86

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cites work

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p53, the cellular gatekeeper for growth and division

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Regulation and function of the p53 tumor suppressor protein

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Mammalian G1- and S-phase checkpoints in response to DNA damage

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p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis

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Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb

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Chk1 and Chk2 kinases in checkpoint control and cancer

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The many substrates and functions of ATM

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The DNA damage response: putting checkpoints in perspective

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Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

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The evolution of diverse biological responses to DNA damage: insights from yeast and p53.

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Chk2 activates E2F-1 in response to DNA damage

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Definition of a consensus binding site for p53

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Targeting the checkpoint kinases: chemosensitization versus chemoprotection

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Nuclear factor - kappaB-dependent regulation of p53 gene expression induced by daunomycin genotoxic drug

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Enhancement of p53-dependent gene activation by the transcriptional coactivator Zac1

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The p53 tumor suppressor targets a novel regulator of G protein signaling

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Benzo[a]pyrene activates the human p53 gene through induction of nuclear factor kappaB activity

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Substrate specificities and identification of putative substrates of ATM kinase family members

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Utilization of oriented peptide libraries to identify substrate motifs selected by ATM.

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Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter

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Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb

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E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

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DNA damage-induced activation of p53 by the checkpoint kinase Chk2

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Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression

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