Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing (Q24339591)

TARBP2 subunit of RISC loading complex

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Protein activator of interferon induced protein kinase EIF2AK2

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Argonaute RISC catalytic component 2

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author

Jennifer Doudna

5

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Kaihong Zhou

2

object named as

Kaihong Zhou

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author name string

Ho Young Lee

1

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Alison Marie Smith

3

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Cameron L Noland

Creative Commons Attribution 3.0 Unported

4

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language of work or name

English

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publication date

July 2013

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published in

Nucleic Acids Research

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volume

41

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page(s)

6568-76

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issue

13

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copyright license

start time

4 October 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling

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In vitro reconstitution of the human RISC-loading complex

19 March 2017

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Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA

19 March 2017

1 reference

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RDE-4 preferentially binds long dsRNA and its dimerization is necessary for cleavage of dsRNA to siRNA.

19 March 2017

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The role of PACT in the RNA silencing pathway

19 March 2017

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A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

19 March 2017

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TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

19 March 2017

1 reference

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

19 March 2017

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Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

19 March 2017

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Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells

19 March 2017

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Biogenesis of small RNAs in animals

19 March 2017

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Precursor microRNA-programmed silencing complex assembly pathways in mammals

19 March 2017

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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

19 March 2017

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Merlin, a tumor suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity

19 March 2017

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R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

19 March 2017

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Multiple sensors ensure guide strand selection in human RNAi pathways

7 April 2017

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Dicer partner proteins tune the length of mature miRNAs in flies and mammals

27 September 2017

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TRBP alters human precursor microRNA processing in vitro

27 September 2017

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Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation

27 September 2017

1 reference

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Substrate-specific kinetics of Dicer-catalyzed RNA processing

27 September 2017

1 reference

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Characterization of the TRBP domain required for dicer interaction and function in RNA interference

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711433

dsRNA binding properties of RDE-4 and TRBP reflect their distinct roles in RNAi

27 September 2017

1 reference

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Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila

27 September 2017

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The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans

27 September 2017

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Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR.

27 September 2017

1 reference

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Structures of the first and second double-stranded RNA-binding domains of human TAR RNA-binding protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711433

PACT, a stress-modulated cellular activator of interferon-induced double-stranded RNA-activated protein kinase, PKR.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711433

The carboxy-terminal, M3 motifs of PACT and TRBP have opposite effects on PKR activity

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKT361

The TAR RNA-binding Protein, TRBP, Stimulates the Expression of TAR-containing RNAsin Vitroandin VivoIndependently of Its Ability to Inhibit the dsRNA-dependent Kinase PKR

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKT361

21 January 2018

Identifiers

DOI

10.1093/NAR/GKT361

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1330131

1330131

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1 reference

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