mTOR is a key modulator of ageing and age-related disease (Q24610741)

Short-term calorie restriction enhances skeletal muscle stem cell function

Europe PubMed Central

title

mTOR is a key modulator of ageing and age-related disease (English)

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main subject

MTOR

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aging-associated disease

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3

Matt Kaeberlein

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author name string

Simon C Johnson

series ordinal

1

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Peter S Rabinovitch

series ordinal

2

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language of work or name

English

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publication date

17 January 2013

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published in

Nature

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volume

493

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page(s)

338-45

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issue

7432

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cites work

1 reference

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mTOR regulates memory CD8 T-cell differentiation

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

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Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9

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TSC2 mediates cellular energy response to control cell growth and survival

7 April 2017

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MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae.

7 April 2017

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TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO

7 April 2017

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Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

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Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

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mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23325216

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE11861

1 reference

Dimensions Publication ID

81789

1019515245

0 references

81789

1 reference

1 reference

1 reference