Regulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cells (Q24646815)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20042122%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Regulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cells (English)

1 reference

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16 January 2020

0 references

1 reference

6

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16 January 2020

Ana Ramírez De Molina

3

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16 January 2020

Juan Carlos Lacal

5

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16 January 2020

author name string

Boon Tin Chua

1

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16 January 2020

David Gallego-Ortega

2

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16 January 2020

Axel Ullrich

4

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16 January 2020

language of work or name

English

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publication date

31 December 2009

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16 January 2020

1 reference

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16 January 2020

volume

8

1 reference

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16 January 2020

issue

1

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page(s)

131

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

16 January 2020

cites work

1 reference

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Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

7 April 2017

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3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

7 April 2017

1 reference

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Choline kinase down-regulation increases the effect of 5-fluorouracil in breast cancer cells

7 April 2017

1 reference

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Phosphocholine as a biomarker of breast cancer: molecular and biochemical studies

7 April 2017

1 reference

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PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth

7 April 2017

1 reference

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Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancers

7 April 2017

1 reference

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Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: implications in cancer therapy.

7 April 2017

1 reference

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Expression of choline kinase alpha to predict outcome in patients with early-stage non-small-cell lung cancer: a retrospective study.

27 September 2017

1 reference

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Therapeutic targets and biomarkers identified in cancer choline phospholipid metabolism

27 September 2017

1 reference

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Protein kinase Cepsilon activates protein kinase B/Akt via DNA-PK to protect against tumor necrosis factor-alpha-induced cell death

27 September 2017

1 reference

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RNA interference-mediated choline kinase suppression in breast cancer cells induces differentiation and reduces proliferation

27 September 2017

1 reference

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The Akt/PKB pathway: molecular target for cancer drug discovery

27 September 2017

1 reference

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Alterations of choline phospholipid metabolism in ovarian tumor progression

27 September 2017

1 reference

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Choline kinase inhibition induces the increase in ceramides resulting in a highly specific and selective cytotoxic antitumoral strategy as a potential mechanism of action.

27 September 2017

1 reference

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PI3K/Akt signalling pathway and cancer.

27 September 2017

1 reference

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Clinical utility of proton magnetic resonance spectroscopy in characterizing breast lesions

27 September 2017

1 reference

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Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806310

Immortalization and transformation are associated with specific alterations in choline metabolism.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806310

Elevated phosphocholine concentration in ras-transformed NIH 3T3 cells arises from increased choline kinase activity, not from phosphatidylcholine breakdown

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806310

Studies of human tumors by MRS: a review

27 September 2017

1 reference

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Early increase in choline kinase activity upon induction of the H-ras oncogene in mouse fibroblast cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806310

PRL-3 initiates tumor angiogenesis by recruiting endothelial cells in vitro and in vivo.

27 September 2017

1 reference

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Inhibition of ChoK is an efficient antitumor strategy for Harvey-, Kirsten-, and N-ras-transformed cells.

30 May 2018

1 reference

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Phosphorylcholine: a novel second messenger essential for mitogenic activity of growth factors.

30 May 2018

1 reference

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Generation of phosphorylcholine as an essential event in the activation of Raf-1 and MAP-kinases in growth factors-induced mitogenic stimulation.

30 May 2018

1 reference

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Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models

30 May 2018

1 reference

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Choline kinase is a novel oncogene that potentiates RhoA-induced carcinogenesis.

28 November 2018

1 reference

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Protein kinase C betaII regulates Akt phosphorylation on Ser-473 in a cell type- and stimulus-specific fashion.

28 November 2018

1 reference

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Regulation of protein kinase B/Akt activity and Ser473 phosphorylation by protein kinase Calpha in endothelial cells

28 November 2018

1 reference

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Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells.

28 November 2018

1 reference

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Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1.

28 November 2018

1 reference

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Diacylglycerol production in Xenopus laevis oocytes after microinjection of p21ras proteins is a consequence of activation of phosphatidylcholine metabolism

28 November 2018

1 reference

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Novel source of 1,2-diacylglycerol elevated in cells transformed by Ha-ras oncogene

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20042122

12 December 2020

inferred from PubMed ID database lookup

Phosphatidylcholine metabolism in human endothelial cells: modulation by phosphocholine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20042122

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/1476-4598-8-131

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/owgicyiokje7jpbgidbtty33qa

30 July 2022

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1476-4598-8-131

Fatcat ID

release_owgicyiokje7jpbgidbtty33qa

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/owgicyiokje7jpbgidbtty33qa

30 July 2022

OpenCitations bibliographic resource ID

599118

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://api.fatcat.wiki/v0/release/owgicyiokje7jpbgidbtty33qa

30 July 2022

https://api.fatcat.wiki/v0/release/owgicyiokje7jpbgidbtty33qa

PubMed publication ID

1 reference

30 July 2022