The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP (Q24650089)

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25 December 2019

title

The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP (English)

1 reference

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neurofibromatosis type II

25 December 2019

main subject

cell line

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1 reference

1 reference

5

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25 December 2019

author name string

Katherine Striedinger

1

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25 December 2019

Scott R VandenBerg

2

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25 December 2019

Gilson S Baia

3

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25 December 2019

Michael W McDermott

4

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25 December 2019

Anita Lal

6

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25 December 2019

language of work or name

English

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publication date

1 November 2008

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25 December 2019

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25 December 2019

volume

10

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25 December 2019

issue

11

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25 December 2019

page(s)

1204-1212

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describes a project that uses

25 December 2019

MENII-1

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cites work

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Neurofibromatosis 2 (NF2) tumor suppressor schwannomin and its interacting protein HRS regulate STAT signaling

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Serine 518 phosphorylation modulates merlin intramolecular association and binding to critical effectors important for NF2 growth suppression

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7 April 2017

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WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus

7 April 2017

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salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

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The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44

7 April 2017

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Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein.

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hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

7 April 2017

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Natural history of meningioma development in mice reveals: a synergy of Nf2 and p16(Ink4a) mutations

28 September 2017

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28 September 2017

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Contact-dependent inhibition of EGFR signaling by Nf2/Merlin

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

28 September 2017

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28 September 2017

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The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression

28 September 2017

1 reference

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Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L

28 September 2017

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Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function.

28 September 2017

1 reference

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Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis

28 September 2017

1 reference

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Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse

28 September 2017

1 reference

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ERM proteins and NF2 tumor suppressor: the Yin and Yang of cortical actin organization and cell growth signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570596

The role of lats in cell cycle regulation and tumorigenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570596

An anti-Ras function of neurofibromatosis type 2 gene product (NF2/Merlin).

28 September 2017

1 reference

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Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570596

The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570596

Cyclin-dependent regulation of G1 in mammalian fibroblasts.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570596

Establishment of a human malignant meningioma cell line with amplified c-myc oncogene

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570596

Expression of the hypoxia marker carbonic anhydrase 9 is associated with anaplastic phenotypes in meningiomas

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570596

Stable suppression of tumorigenicity by virus-mediated RNA interference

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570596

Paxillin binds schwannomin and regulates its density-dependent localization and effect on cell morphology

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570596

Transduction of wild-type merlin into human schwannoma cells decreases schwannoma cell growth and induces apoptosis

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18953429

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18953429

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1593/NEO.08642

2 references

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25 December 2019

1 reference

2 references

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25 December 2019

2 references