A Systems Biology Overview on Human Diabetic Nephropathy: From Genetic Susceptibility to Post-Transcriptional and Post-Translational Modifications (Q26769678)

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English	A Systems Biology Overview on Human Diabetic Nephropathy: From Genetic Susceptibility to Post-Transcriptional and Post-Translational Modifications	scientific article

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scholarly article

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4 references

18 November 2020

20 December 2020

4 February 2021

29 June 2021

A Systems Biology Overview on Human Diabetic Nephropathy: From Genetic Susceptibility to Post-Transcriptional and Post-Translational Modifications (English)

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type 2 diabetes

2 references

18 November 2020

4 February 2021

post-transcriptional modification

2 references

8 September 2019

20 December 2020

post-translational protein modification

2 references

29 June 2021

diabetic nephropathy

4 references

18 November 2020

20 December 2020

4 February 2021

29 June 2021

1 reference

18 November 2020

systems biology

1 reference

Francesca Conserva

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26798653%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

3

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11 June 2020

author name string

Loreto Gesualdo

2

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11 June 2020

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2016

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20 December 2015

10 references

13 March 2019

14 March 2019

24 March 2019

8 September 2019

9 October 2019

31 August 2020

18 November 2020

20 December 2020

4 February 2021

29 June 2021

Journal of Diabetes Research

12 references

13 March 2019

14 March 2019

24 March 2019

8 September 2019

9 October 2019

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26798653%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

31 August 2020

18 November 2020

20 December 2020

4 February 2021

29 June 2021

2016

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26798653%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

7934504

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11 June 2020

copyright license

Creative Commons Attribution 4.0 International

11 references

Europe PubMed Central

13 March 2019

Europe PubMed Central

14 March 2019

Europe PubMed Central

24 March 2019

Europe PubMed Central

8 September 2019

Europe PubMed Central

9 October 2019

Europe PubMed Central

29 May 2020

Europe PubMed Central

31 August 2020

Europe PubMed Central

18 November 2020

Europe PubMed Central

20 December 2020

Europe PubMed Central

4 February 2021

Europe PubMed Central

29 June 2021

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on focus list of Wikimedia project

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Role of podocyte B7-1 in diabetic nephropathy

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28 September 2017

Urine and plasma metabolites predict the development of diabetic nephropathy in individuals with Type 2 diabetes mellitus.

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28 September 2017

Proteomics and diabetic nephropathy: what have we learned from a decade of clinical proteomics studies?

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28 September 2017

Predictive significance of kidney myeloid-related protein 8 expression in patients with obesity- or type 2 diabetes-associated kidney diseases

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28 September 2017

Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease

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28 September 2017

Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy

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28 September 2017

Urinary miR-29 correlates with albuminuria and carotid intima-media thickness in type 2 diabetes patients

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28 September 2017

Urinary exosomal microRNAs in incipient diabetic nephropathy

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28 September 2017

Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: implications for diabetic nephropathy

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28 September 2017

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes

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28 September 2017

Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease

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28 September 2017

A potentially functional polymorphism in the regulatory region of let-7a-2 is associated with an increased risk for diabetic nephropathy

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28 September 2017

Regulation of TIMP3 in diabetic nephropathy: a role for microRNAs.

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28 September 2017

Family-based association analysis confirms the role of the chromosome 9q21.32 locus in the susceptibility of diabetic nephropathy

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28 September 2017

Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay

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28 September 2017

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Urinary proteomics for early diagnosis in diabetic nephropathy

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A pilot trial assessing urinary gene expression profiling with an mRNA array for diabetic nephropathy

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Metabolomics: the final frontier?

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Differential proteome profiling using iTRAQ in microalbuminuric and normoalbuminuric type 2 diabetic patients

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Next-generation sequencing identifies TGF-β1-associated gene expression profiles in renal epithelial cells reiterated in human diabetic nephropathy

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Pathology of human diabetic nephropathy

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28 September 2017

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Functional characterization of the plasmacytoma variant translocation 1 gene (PVT1) in diabetic nephropathy

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28 September 2017

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28 September 2017

Genetic associations in diabetic nephropathy: a meta-analysis

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28 September 2017

Pathogenic role of TGF-β in the progression of podocyte diseases

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28 September 2017

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28 September 2017

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

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28 September 2017

Urine proteome analysis may allow noninvasive differential diagnosis of diabetic nephropathy

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28 September 2017

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28 September 2017

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28 September 2017

Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis

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28 September 2017

MicroRNA control of signal transduction

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28 September 2017

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28 September 2017

Metabolomics applied to diabetes research: moving from information to knowledge

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28 September 2017

Mouse models of diabetic nephropathy

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28 September 2017

Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy

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28 September 2017

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes

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28 September 2017

Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease

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28 September 2017

Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy

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28 September 2017

Proteinuria and hyperglycemia induce endoplasmic reticulum stress

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28 September 2017

MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy

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28 September 2017

Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis

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28 September 2017

Affinity separation and enrichment methods in proteomic analysis

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28 September 2017

Chronic kidney disease prevalence estimates among racial/ethnic groups: the Multi-Ethnic Study of Atherosclerosis

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28 September 2017

IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis.

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28 September 2017

Urinary proteomics in diabetes and CKD

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28 September 2017

The death ligand TRAIL in diabetic nephropathy

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28 September 2017

Increased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycaemic control

1 reference

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28 September 2017

Co-regulation of Gremlin and Notch signalling in diabetic nephropathy

1 reference

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28 September 2017

Variants in the plasmacytoma variant translocation gene (PVT1) are associated with end-stage renal disease attributed to type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

28 September 2017

Characterization of diabetic nephropathy by urinary proteomic analysis: identification of a processed ubiquitin form as a differentially excreted protein in diabetic nephropathy patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

28 September 2017

MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.

1 reference

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28 September 2017

Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress.

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28 September 2017

Reduction of VEGF-A and CTGF expression in diabetic nephropathy is associated with podocyte loss.

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28 September 2017

Distinguishing diabetic nephropathy from other causes of glomerulosclerosis: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

28 September 2017

Genetics of Kidneys in Diabetes (GoKinD) study: a genetics collection available for identifying genetic susceptibility factors for diabetic nephropathy in type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

28 September 2017

Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

28 September 2017

Messenger RNA expression of glomerular podocyte markers in the urinary sediment of acquired proteinuric diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

28 September 2017

Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

28 September 2017

The case for intrarenal hypertension in the initiation and progression of diabetic and other glomerulopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

28 September 2017

Endocytosis, transfer tubules, and lysosomal activity in myeloid sinusoidal endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

28 September 2017

Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

31 May 2018

Identification of diabetic nephropathy-selective proteins in human plasma by multi-lectin affinity chromatography and LC-MS/MS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

31 May 2018

Pluripotent protective effects of carnosine, a naturally occurring dipeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

31 May 2018

Familial clustering of diabetic kidney disease. Evidence for genetic susceptibility to diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698547

31 May 2018

Different patterns of renal damage in type 2 diabetes mellitus: a multicentric study on 393 biopsies.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Pathologic classification of diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

D18S880 microsatellite polymorphism of carnosinase gene and diabetic nephropathy: a meta-analysis

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Tissue gene expression of renin-angiotensin system in human type 2 diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Collagen type VIII expression in human diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Role of basic fibroblast growth factor (FGF-2) in diabetic nephropathy and mechanisms of its induction by hyperglycemia in human renal fibroblasts

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Epithelial-mesenchymal transition as a potential explanation for podocyte depletion in diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Over-expression of platelet-derived growth factor in human diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Expression and regulation of a novel identified TNFAIP8 family is associated with diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Quantitave and qualitative changes in vascular endothelial growth factor gene expression in glomeruli of patients with type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Decreased p66Shc promoter methylation in patients with end-stage renal disease

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

A urinary peptide biomarker set predicts worsening of albuminuria in type 2 diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Metabonomics research of diabetic nephropathy and type 2 diabetes mellitus based on UPLC-oaTOF-MS system

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Ultraviolet and tandem mass spectrometry for simultaneous quantification of 21 pivotal metabolites in plasma from patients with diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Phospholipidomic identification of potential plasma biomarkers associated with type 2 diabetes mellitus and diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Plasma phospholipid transfer protein activity and small, dense LDL in type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Simultaneous determination and quantification of seven major phospholipid classes in human blood using normal-phase liquid chromatography coupled with electrospray mass spectrometry and the application in diabetes nephropathy

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

The TGF- Route to Renal Fibrosis Is Not Linear: The miR-21 Viaduct

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Gene for susceptibility to diabetic nephropathy in type 2 diabetes maps to 18q22.3-23

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F7934504

21 January 2018

Proteome analysis of serum from type 2 diabetics with nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic profiling reveals new serum biomarkers for differentiating diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ELMO1 increases expression of extracellular matrix proteins and inhibits cell adhesion to ECMs

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma esterified and non-esterified fatty acids metabolic profiling using gas chromatography-mass spectrometry and its application in the study of diabetic mellitus and diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early detection of patients at risk of developing diabetic nephropathy. A longitudinal study of urinary albumin excretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of urotensin II and urotensin II receptor in human diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opening a treasure chest: glomerular proteome analyses of formalin-fixed paraffin-embedded kidney tissue in the investigation of diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advanced glycation end-products suppress neuropilin-1 expression in podocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urinary sediment miRNA levels in adult nephrotic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor gene expression is correlated with glomerular neovascularization in human diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced glomerular Toll-like receptor 4 expression and signaling in patients with type 2 diabetic nephropathy and microalbuminuria

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The discovery of biomarkers for type 2 diabetic nephropathy by serum proteome analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Messenger RNA expression of podocyte-associated molecules in the urinary sediment of patients with diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of human nephrin mRNA in diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genome scan for diabetic nephropathy in African Americans

1 reference

https://pubmed.ncbi.nlm.nih.gov/26798653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2016/7934504

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26798653%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26798653%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26798653%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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