MEG3 noncoding RNA: a tumor suppressor (Q26823948)

Crossref

X. Zhang

series ordinal

2

1 reference

Crossref

A. Klibanski

series ordinal

3

1 reference

Crossref

language of work or name

1 reference

June 2012

1 reference

Journal of Molecular Endocrinology

published in

1 reference

volume

48

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issue

3

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page(s)

R45-53

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Maternally expressed gene 3 (MEG3) noncoding ribonucleic acid: isoform structure, expression, and functions

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A Pituitary-Derived MEG3 Isoform Functions as a Growth Suppressor in Tumor Cells

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Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression

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Selective loss of MEG3 expression and intergenic differentially methylated region hypermethylation in the MEG3/DLK1 locus in human clinically nonfunctioning pituitary adenomas

7 April 2017

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Loss of expression of GADD45 gamma, a growth inhibitory gene, in human pituitary adenomas: implications for tumorigenesis

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Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation

7 April 2017

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Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene

7 April 2017

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Increased expression of angiogenic genes in the brains of mouse meg3-null embryos

7 April 2017

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Deletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice

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The mouse Gtl2 gene is differentially expressed during embryonic development, encodes multiple alternatively spliced transcripts, and may act as an RNA

7 April 2017

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Differential regulation of imprinting in the murine embryo and placenta by the Dlk1-Dio3 imprinting control region

7 April 2017

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Blinded by the Light: The Growing Complexity of p53

7 April 2017

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The p53 pathway: positive and negative feedback loops

7 April 2017

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Role of angiogenesis in tumor growth and metastasis

7 April 2017

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Effects of an Rb mutation in the mouse

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Overexpression of the long non-coding RNA MEG3 impairs in vitro glioma cell proliferation

7 April 2017

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Silencing of the imprinted DLK1-MEG3 locus in human clinically nonfunctioning pituitary adenomas

28 September 2017

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TP53 mutations in human cancer: database reassessment and prospects for the next decade

28 September 2017

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p53 regulation by ubiquitin

28 September 2017

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The functional role of long non-coding RNA in human carcinomas

28 September 2017

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The IG-DMR and the MEG3-DMR at human chromosome 14q32.2: hierarchical interaction and distinct functional properties as imprinting control centers

28 September 2017

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TP53 mutations in human cancers: origins, consequences, and clinical use

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Genomic imprinting at the mammalian Dlk1-Dio3 domain

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Cyclic AMP stimulates MEG3 gene expression in cells through a cAMP-response element (CRE) in the MEG3 proximal promoter region

28 September 2017

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Epigenetic alteration at the DLK1-GTL2 imprinted domain in human neoplasia: analysis of neuroblastoma, phaeochromocytoma and Wilms' tumour

28 September 2017

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28 September 2017

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The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network

28 September 2017

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Epigenetic analysis of the Dlk1-Gtl2 imprinted domain on mouse chromosome 12: implications for imprinting control from comparison with Igf2-H19.

28 September 2017

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Comparative sequence analysis of the imprinted Dlk1-Gtl2 locus in three mammalian species reveals highly conserved genomic elements and refines comparison with the Igf2-H19 region.

28 September 2017

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Animal models of tumor-suppressor genes.

28 September 2017

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Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14q.

28 September 2017

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A human pituitary tumor-derived folliculostellate cell line

28 September 2017

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28 September 2017

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VEGFs, receptors and angiogenesis

28 September 2017

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Clinically nonfunctioning pituitary tumors are monoclonal in origin

28 September 2017

1 reference

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microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer

28 September 2017

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Clonal origin of pituitary adenomas

31 May 2018

1 reference

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Requirement for a functional Rb-1 gene in murine development

31 May 2018

1 reference

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Clonal origins of adrenocorticotropin-secreting pituitary tissue in Cushing's disease

31 May 2018

1 reference

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Expression of cell growth negative regulators MEG3 and GADD45γ is lost in most sporadic human pituitary adenomas

31 May 2018

1 reference

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Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738193

Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738193

Loss of Expression ofGADD45γ, a Growth Inhibitory Gene, in Human Pituitary Adenomas: Implications for Tumorigenesis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3738193

28 November 2018

Tumor suppressor genes

1 reference

12 December 2020

Tumor suppressor genes

1 reference

12 December 2020

Loss of heterozygosity on chromosome 14 in nasopharyngeal carcinoma

1 reference

12 December 2020

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

1 reference

12 December 2020

Loss of heterozygosity of 14q32 in colorectal carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1530/JME-12-0008

1 reference

1 reference

1 reference

PubMed publication ID

22393162

1 reference