The role of Bcl-2 family proteins in therapy responses of malignant astrocytic gliomas: Bcl2L12 and beyond (Q26851645)

Samuel A. Jensen

series ordinal

2

1 reference

Alexander H. Stegh

series ordinal

3

1 reference

language of work or name

1 reference

2012

1 reference

The Scientific World Journal

14 February 2012

5 references

3 April 2019

25 April 2019

2 August 2019

20 November 2019

18 December 2019

6 references

3 April 2019

25 April 2019

2 August 2019

20 November 2019

18 December 2019

2012

1 reference

page(s)

838916

1 reference

Creative Commons Attribution 3.0 Unported

copyright license

5 references

3 April 2019

25 April 2019

2 August 2019

20 November 2019

on focus list of Wikimedia project

18 December 2019

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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7 April 2017

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MicroRNAs: genomics, biogenesis, mechanism, and function

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Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics

22 April 2017

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7 April 2017

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7 April 2017

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BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations

7 April 2017

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7 April 2017

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Malignant gliomas in adults

7 April 2017

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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

7 April 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Intratumoral mediated immunosuppression is prognostic in genetically engineered murine models of glioma and correlates to immunotherapeutic responses

28 September 2017

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Homeostatic functions of BCL-2 proteins beyond apoptosis

28 September 2017

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MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

28 September 2017

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A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications

28 September 2017

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STAT3 inhibitor WP1066 as a novel therapeutic agent for renal cell carcinoma

28 September 2017

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BIM induction of apoptosis triggered by EGFR-sensitive and resistance cell lines of non-small-cell lung cancer

28 September 2017

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EGFR and EGFRvIII interact with PUMA to inhibit mitochondrial translocalization of PUMA and PUMA-mediated apoptosis independent of EGFR kinase activity.

28 September 2017

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Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim.

28 September 2017

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28 September 2017

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Downregulations of B-cell lymphoma 2 and myeloid cell leukemia sequence 1 by microRNA 153 induce apoptosis in a glioblastoma cell line DBTRG-05MG.

28 September 2017

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Functional delivery of siRNA in mice using dendriworms

28 September 2017

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Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma

28 September 2017

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Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins

28 September 2017

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Cancer stem cells and glioma

28 September 2017

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Proapoptotic BH3-only BCL-2 family protein BIM connects death signaling from epidermal growth factor receptor inhibition to the mitochondrion

28 September 2017

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28 September 2017

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A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo

28 September 2017

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Necrotic death as a cell fate

28 September 2017

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Investigations on gossypol: past and present developments

28 September 2017

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A role for proapoptotic BID in the DNA-damage response

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Molecular cloning, physical mapping, and expression analysis of a novel gene, BCL2L12, encoding a proline-rich protein with a highly conserved BH2 domain of the Bcl-2 family

28 September 2017

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28 September 2017

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28 September 2017

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What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator.

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The small organic compound HA14-1 prevents Bcl-2 interaction with Bax to sensitize malignant glioma cells to induction of cell death.

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21 January 2018

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EGFR-dependent downregulation of Bim in epithelial cells requires MAPK and PKC-delta activities

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