Are either or both hyperuricemia and xanthine oxidase directly toxic to the vasculature? A critical appraisal (Q26862468)

2

1 reference

Sushma Rekhraj

3

1 reference

Allan D. Struthers

4

1 reference

Hyon Choi

5

1 reference

Robert A. Terkeltaub

6

1 reference

language of work or name

1 reference

February 2012

1 reference

published in

Arthritis & Rheumatology

1 reference

volume

64

1 reference

page(s)

327-38

1 reference

issue

2

1 reference

Effect of allopurinol in chronic kidney disease progression and cardiovascular risk

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Human vascular smooth muscle cells express a urate transporter

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Towards the physiological function of uric acid

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Xanthine oxidoreductase is central to the evolution and function of the innate immune system

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Completing the uric acid degradation pathway through phylogenetic comparison of whole genomes

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Mechanistic insights into the therapeutic use of high-dose allopurinol in angina pectoris.

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Urate as a physiological substrate for myeloperoxidase: implications for hyperuricemia and inflammation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-{gamma} sumoylation, and HIF-1{alpha}

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Treating gout with pegloticase, a PEGylated urate oxidase, provides insight into the importance of uric acid as an antioxidant in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Impaired S-nitrosylation of the ryanodine receptor caused by xanthine oxidase activity contributes to calcium leak in heart failure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Uric acid promotes an acute inflammatory response to sterile cell death in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Uric acid and hypertension: cause or effect?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Radicals in the reaction between peroxynitrite and uric acid identified by electron spin resonance spectroscopy and liquid chromatography mass spectrometry

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Uric acid-lowering treatment with benzbromarone in patients with heart failure: a double-blind placebo-controlled crossover preliminary study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Allopurinol for pain relief: more than just crystal clearance?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Uric acid: the oxidant-antioxidant paradox

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Altered uric acid levels and disease states

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Hypothesis: fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Febuxostat compared with allopurinol in patients with hyperuricemia and gout

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

A causal role for uric acid in fructose-induced metabolic syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Oxypurinol improves coronary and peripheral endothelial function in patients with coronary artery disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Xanthine oxidase inhibitors improve energetics and function after infarction in failing mouse hearts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Vitamin C biosynthesis in trypanosomes: a role for the glycosome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Allopurinol reduces B-type natriuretic peptide concentrations and haemoglobin but does not alter exercise capacity in chronic heart failure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Uric acid in chronic heart failure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Risk of myocardial infarction and stroke after acute infection or vaccination

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Neuronal nitric oxide synthase negatively regulates xanthine oxidoreductase inhibition of cardiac excitation-contraction coupling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Hyperuricaemia does not impair cardiovascular function in healthy adults

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Inosine exerts a broad range of antiinflammatory effects in a murine model of acute lung injury

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Anti-inflammatory effects of inosine in human monocytes, neutrophils and epithelial cells in vitro.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Functional analysis and molecular modeling of a cloned urate transporter/channel

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Asymptomatic hyperuricemia. Risks and consequences in the Normative Aging Study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Xanthine oxidase: biochemistry, distribution and physiology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Role of reactive oxygen metabolites in experimental colitis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Sulfinpyrazone in the prevention of cardiac death after myocardial infarction. The Anturane Reinfarction Trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

The mechanism of conversion of rat liver xanthine dehydrogenase from an NAD+-dependent form (type D) to an O2-dependent form (type O)

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Inactivation of nitric oxide by uric acid

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Hyperuricemia induces endothelial dysfunction

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Uric acid reduces exercise-induced oxidative stress in healthy adults

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Aspirin, sulfinpyrazone, or both in unstable angina. Results of a Canadian multicenter trial.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Uric acid-iron ion complexes. A new aspect of the antioxidant functions of uric acid.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Human liver xanthine oxidase: Nature and extent of individual variation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Inhibition of xanthine oxidase by uric acid and its influence on superoxide radical production

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Elevated serum uric acid levels are associated with diastolic dysfunction in patients with dilated cardiomyopathy.

31 May 2018

1 reference

Simultaneous determination of uric acid metabolites allantoin, 6-aminouracil, and triuret in human urine using liquid chromatography-mass spectrometry

21 January 2018

1 reference

Urate produced during hypoxia protects heart proteins from peroxynitrite-mediated protein nitration

21 January 2018

1 reference

Systemic uric acid administration increases serum antioxidant capacity in healthy volunteers

21 January 2018

1 reference

Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin-angiotensin system

21 January 2018

1 reference

Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2.

21 January 2018

1 reference

Uric acid causes vascular smooth muscle cell proliferation by entering cells via a functional urate transporter

21 January 2018

1 reference

Uric acid-induced C-reactive protein expression: implication on cell proliferation and nitric oxide production of human vascular cells

21 January 2018

1 reference

Effect of elevated serum uric acid on cisplatin-induced acute renal failure.

21 January 2018

1 reference

Hyperuricemia exacerbates chronic cyclosporine nephropathy.

21 January 2018

1 reference

Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid level

21 January 2018

1 reference

The impact of serum uric acid on cardiovascular outcomes in the LIFE study

21 January 2018

1 reference

Lowering serum urate does not improve endothelial function in patients with type 2 diabetes

21 January 2018

1 reference

The relation of postmenopausal hormone therapy to serum uric acid and the risk of coronary heart disease events: the Heart and Estrogen-Progestin Replacement Study (HERS).

21 January 2018

1 reference

Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial

21 January 2018

1 reference

Identification of uric acid and xanthine oxidase in atherosclerotic plaque

21 January 2018

1 reference

Antioxidant status and purine bases in carotid artery plaque.

21 January 2018

1 reference

Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation

21 January 2018

1 reference

Cytokine-mediated xanthine oxidase upregulation in chronic obstructive pulmonary disease's airways

21 January 2018

1 reference

Upregulation of xanthine oxidase by tobacco smoke condensate in pulmonary endothelial cells

21 January 2018

1 reference

Cardiac depressant effects of oxygen free radicals.

21 January 2018

1 reference

Allopurinol improves endothelial dysfunction in chronic heart failure

21 January 2018

1 reference

Allopurinol attenuates left ventricular remodeling and dysfunction after experimental myocardial infarction: a new action for an old drug?

21 January 2018

1 reference

Impact of oxypurinol in patients with symptomatic heart failure. Results of the OPT-CHF study

21 January 2018

1 reference

Xanthine oxidase inhibition ameliorates cardiovascular dysfunction in dogs with pacing-induced heart failure

21 January 2018

1 reference

Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy

21 January 2018

1 reference

Clinical trials update from the Heart Failure Society of America meeting: FIX-CHF-4, selective cardiac myosin activator and OPT-CHF.

21 January 2018

1 reference

Vascular and hepatocellular peroxynitrite formation during acetaminophen toxicity: role of mitochondrial oxidant stress

21 January 2018

1 reference

Effects of rosuvastatin on myeloperoxidase levels in patients with chronic heart failure: a randomized placebo-controlled study

21 January 2018

1 reference

Effect of allopurinol on brain adenosine levels during hypoxia in newborn piglets

21 January 2018

1 reference

Immunomodulatory effect of the purine nucleoside inosine following spinal cord contusion injury in rat.

21 January 2018

1 reference

Inosine inhibits inflammatory cytokine production by a posttranscriptional mechanism and protects against endotoxin-induced shock

21 January 2018

1 reference

Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism.

21 January 2018

1 reference

Quantification of Total Oxidant Scavenging Capacity of Antioxidants for Peroxynitrite, Peroxyl Radicals, and Hydroxyl Radicals

21 January 2018

1 reference

Enhanced Expression and Activity of Xanthine Oxidoreductase in the Failing Heart

21 January 2018

1 reference

Effect of allopurinol in decreasing proteinuria in type 2 diabetic patients

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Mouse transthyretin-related protein is a hydrolase which degrades 5-hydroxyisourate, the end product of the uricase reaction.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265683

Increasing prevalence of gout and hyperuricemia over 10 years among older adults in a managed care population

28 November 2018

1 reference

12 December 2020

Sulfinpyrazone in the prevention of sudden death after myocardial infarction

1 reference

12 December 2020

Purine bases and atheromatous plaque

1 reference

12 December 2020

The effect of xanthine oxidase inhibition upon ejection fraction in heart failure patients: La Plata Study

1 reference

12 December 2020

Uric acid restores endothelial function in patients with type 1 diabetes and regular smokers

1 reference

12 December 2020

Allopurinol Normalizes Endothelial Dysfunction in Type 2 Diabetics With Mild Hypertension

1 reference

12 December 2020

Reaction of uric acid with peroxynitrite and implications for the mechanism of neuroprotection by uric acid

1 reference

12 December 2020

Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP)

1 reference

12 December 2020

Sulphinpyrazone in post-myocardial infarction. Report from the Anturan Reinfarction Italian Study

1 reference

12 December 2020

Role of xanthine oxidase inhibitor as free radical scavenger: a novel mechanism of action of allopurinol and oxypurinol in myocardial salvage

1 reference

12 December 2020

On the specificity of allopurinol and oxypurinol as inhibitors of xanthine oxidase. A pulse radiolysis determination of rate constants for reaction of allopurinol and oxypurinol with hydroxyl radicals

1 reference

12 December 2020

Differences in redox and kinetic properties between NAD-dependent and O2-dependent types of rat liver xanthine dehydrogenase

1 reference

12 December 2020

Uric acid stimulates vascular smooth muscle cell proliferation by increasing platelet-derived growth factor A-chain expression

1 reference

12 December 2020

The contribution of vascular endothelial xanthine dehydrogenase/oxidase to oxygen-mediated cell injury

1 reference

12 December 2020

Free radical scavenging and antioxidant activity of allopurinol and oxypurinol in experimental lens-induced uveitis

1 reference

12 December 2020

Circulating xanthine oxidase in human ischemia reperfusion

1 reference

12 December 2020

Pretreatment with antioxidants and allopurinol diminishes cardiac onset events in coronary artery bypass grafting

1 reference

12 December 2020

Podocyte architecture in puromycin aminonucleoside-treated rats administered tungsten or allopurinol

1 reference

12 December 2020

Xanthine oxidase binding to glycosaminoglycans: kinetics and superoxide dismutase interactions of immobilized xanthine oxidase-heparin complexes

1 reference

12 December 2020

Xanthine oxidase inhibition with oxypurinol improves endothelial vasodilator function in hypercholesterolemic but not in hypertensive patients

1 reference

12 December 2020

Xanthine oxidase decreases production of gut wall nitric oxide

1 reference

12 December 2020

Circulating xanthine oxidase and neutrophil activation during human liver transplantation

1 reference

12 December 2020

A reappraisal of xanthine dehydrogenase and oxidase in hypoxic reperfusion injury: the role of NADH as an electron donor

1 reference

12 December 2020

Novel myofilament Ca2+-sensitizing property of xanthine oxidase inhibitors

1 reference

12 December 2020

Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure

1 reference

12 December 2020

Uric acid and cardiovascular risk

1 reference

12 December 2020

Differences in MSU-induced superoxide responses by neutrophils from gout subjects compared to healthy controls and a role for environmental inflammatory cytokines and hyperuricemia in neutrophil function and survival

1 reference

12 December 2020

Involvement of xanthine oxidase and hypoxia-inducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1β

1 reference

12 December 2020

Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007-2008

1 reference

12 December 2020

Studies on the oxidative half-reaction of xanthine oxidase

1 reference

12 December 2020