Prostaglandin E2 and T cells: friends or foes? (Q27021151)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21946663%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references

3 July 2020

3 October 2022

Prostaglandin E2 and T cells: friends or foes? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21946663%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

31 July 2019

cell surface receptor

1 reference

biomedical investigative technique

31 July 2019

1 reference

19 September 2019

1 reference

12 October 2019

hemic and immune systems

1 reference

18 October 2019

1 reference

19 November 2019

1 reference

15 December 2019

1 reference

3 July 2020

3

1 reference

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13 February 2020

author name string

Vinatha Sreeramkumar

series ordinal

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21946663%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Manuel Fresno

series ordinal

2

2 references

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13 February 2020

language of work or name

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27 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21946663%20AND%20SRC:MED&resulttype=core&format=json

Immunology & Cell Biology

13 February 2020

1 July 2012

2 references

3 July 2020

3 October 2022

11 references

31 July 2019

19 September 2019

12 October 2019

18 October 2019

19 November 2019

15 December 2019

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13 February 2020

5 June 2020

3 July 2020

3 October 2022

90

2 references

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13 February 2020

page(s)

579-586

1 reference

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issue

6

2 references

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

13 February 2020

copyright license

9 references

31 July 2019

19 September 2019

12 October 2019

18 October 2019

19 November 2019

15 December 2019

5 June 2020

3 July 2020

Prostaglandin E(2) enhances T-cell proliferation by inducing the costimulatory molecules OX40L, CD70, and 4-1BBL on dendritic cells

3 October 2022

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Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

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Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

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Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse

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Regulation of the MAP kinase cascade

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Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion

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Two isoforms of the EP3 receptor with different carboxyl-terminal domains. Identical ligand binding properties and different coupling properties with Gi proteins

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Third isoform of the prostaglandin-E-receptor EP3 subtype with different C-terminal tail coupling to both stimulation and inhibition of adenylate cyclase

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Prostaglandin E2 modulation of p59fyn tyrosine kinase in T lymphocytes during sepsis

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Calcium signalling: dynamics, homeostasis and remodelling

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Prostanoid receptors: structures, properties, and functions

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Leukotrienes and lipoxins: structures, biosynthesis, and biological effects

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Inositol phosphates and cell signalling

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Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis

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Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer

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PGE2 inhibits natural killer and gamma delta T cell cytotoxicity triggered by NKR and TCR through a cAMP-mediated PKA type I-dependent signaling

28 September 2017

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A novel antagonist of the prostaglandin E(2) EP(4) receptor inhibits Th1 differentiation and Th17 expansion and is orally active in arthritis models

28 September 2017

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Progress in COX-2 inhibitors: a journey so far.

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Prostanoids in health and disease

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Antagonism of the prostaglandin E receptor EP4 inhibits metastasis and enhances NK function

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Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion

28 September 2017

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28 September 2017

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In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells

28 September 2017

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Membrane prostaglandin E synthase-1: a novel therapeutic target

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Mechanism of prostaglandin (PG)E2-induced prolactin expression in human T cells: cooperation of two PGE2 receptor subtypes, E-prostanoid (EP) 3 and EP4, via calcium- and cyclic adenosine 5'-monophosphate-mediated signaling pathways

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.

28 September 2017

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Comparison of agonist-induced internalization of the human EP2 and EP4 prostaglandin receptors: role of the carboxyl terminus in EP4 receptor sequestration.

28 September 2017

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Roles of prostanoids revealed from studies using mice lacking specific prostanoid receptors

28 September 2017

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Prostaglandin E2 primes naive T cells for the production of anti-inflammatory cytokines.

28 September 2017

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Prostaglandin E receptor EP3 subtype induces neurite retraction via small GTPase Rho.

28 September 2017

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28 September 2017

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Role of Ca2+ in prostaglandin E2-induced T-lymphocyte proliferative suppression in sepsis.

28 September 2017

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Regulatory interactions between macrophages and T-cell subsets in Listeria monocytogenes-specific T-cell activation.

28 September 2017

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Regulation of the immune response by prostaglandins

28 September 2017

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28 September 2017

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Human lymphocytic metabolism. Effects of cyclic and noncyclic nucleotides on stimulation by phytohemagglutinin

28 September 2017

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Analysis of prostaglandin E2 effect on T lymphocyte activation. Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12.0 tetradecanoyl phorbol-13 acetate

28 September 2017

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Characterization of prostanoid relaxant/inhibitory receptors (psi) using a highly selective agonist, TR4979.

28 September 2017

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Receptors and phosphoinositide-generated second messengers

28 September 2017

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Prostaglandins and thromboxanes

28 September 2017

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Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling

28 September 2017

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Prostaglandin E2 receptor EP4 contributes to inflammatory pain hypersensitivity.

31 May 2018

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The role of PGE(2) in the differentiation of dendritic cells: how do dendritic cells influence T-cell polarization and chemokine receptor expression?

31 May 2018

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Effects of prostaglandin E2 on Th0-type human T cell clones: modulation of functions of nuclear proteins involved in cytokine production

31 May 2018

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Prostaglandin E2 and other cyclic AMP elevating agents inhibit interleukin 2 gene transcription by counteracting calcineurin-dependent pathways

31 May 2018

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Effect of PGE2 and of agents that raise cAMP levels on macrophage activation induced by IFN-gamma and TNF-alpha.

31 May 2018

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Prostaglandin E2 promotes the induction of anergy during T helper cell recognition of myelin basic protein

31 May 2018

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Prostaglandin E2 acts at two distinct pathways of T lymphocyte activation: inhibition of interleukin 2 production and down-regulation of transferrin receptor expression

31 May 2018

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Phosphatidyl inositol hydrolysis after CD3 binding in human peripheral blood T cells: inhibition by prostaglandin E2.

31 May 2018

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Effects of modulators of adenylyl cyclase on interleukin-2 production, cytosolic Ca2+ elevation, and K+ channel activity in Jurkat T cells

31 May 2018

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A prostaglandin E receptor coupled to a pertussis toxin-sensitive guanine nucleotide regulatory protein in rabbit cortical collecting tubule cells

31 May 2018

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Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines

31 May 2018

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Overexpression of functionally coupled cyclooxygenase-2 and prostaglandin E synthase in symptomatic atherosclerotic plaques as a basis of prostaglandin E(2)-dependent plaque instability

31 May 2018

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Suppression of allergic inflammation by the prostaglandin E receptor subtype EP3.

21 January 2018

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Lipopolysaccharide attenuates mRNA levels of several adenylyl cyclase isoforms in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

Prostaglandin E2 induced functional expression of early growth response factor-1 by EP4, but not EP2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

Identification of a region of the C-terminal domain involved in short-term desensitization of the prostaglandin EP4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

Immunoregulation by macrophages III prostaglandin E suppresses lymphocyte activation but not macrophage effector function during Salmonella enteritidis infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

Prostaglandin E2 and the increase of intracellular cAMP inhibit the expression of interleukin 2 receptors in human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

LPS-activated monocytes suppress T-cell immune responses and induce FOXP3+ T cells through a COX-2-PGE2-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

Combined spatial and enzymatic regulation of Csk by cAMP and protein kinase a inhibits T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

Prostaglandin E2 impairs CD4+ T cell activation by inhibition of lck: implications in Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

Prostaglandin E2 induces interleukin-8 gene transcription by activating C/EBP homologous protein in human T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

Prostaglandin E2 enhances Th17 responses via modulation of IL-17 and IFN-gamma production by memory CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

Maturation of human monocyte-derived dendritic cells (MoDCs) in the presence of prostaglandin E2 optimizes CD4 and CD8 T cell-mediated responses to protein antigens: role of PGE2 in chemokine and cytokine expression by MoDCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

FOXP3+CD4+CD25+ Adaptive Regulatory T Cells Express Cyclooxygenase-2 and Suppress Effector T Cells by a Prostaglandin E2-Dependent Mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

A Critical Role for Prostaglandin E2 in Podosome Dissolution and Induction of High-Speed Migration during Dendritic Cell Maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

Induction of cyclooxygenase-2 on activated T lymphocytes: regulation of T cell activation by cyclooxygenase-2 inhibitors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389798

Prostaglandin E2 and dexamethasone inhibit IL-12 receptor expression and IL-12 responsiveness

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389798

Elevated expression of prostaglandin receptor and increased release of prostaglandin E2 maintain the survival of CD45RO+ T cells in the inflamed human pleural space

28 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2011.75

Prostaglandin E2 inhibits the nuclear transcription of the human interleukin 2, but not the Il-4, gene in human T cells by targeting transcription factors AP-1 and NF-AT

21 January 2018

1 reference

12 December 2020

Signal transduction in Th clones: target of differential modulation by PGE2 may reside downstream of the PKC-dependent pathway

1 reference

12 December 2020

Two Gs-coupled prostaglandin E receptor subtypes, EP2 and EP4, differ in desensitization and sensitivity to the metabolic inactivation of the agonist

1 reference

12 December 2020

PGE(2)-mediated inhibition of T cell p59(fyn) is independent of cAMP

1 reference

12 December 2020

Role of protein kinase C in cyclic AMP-mediated suppression of T-lymphocyte activation following burn injury

1 reference

12 December 2020

Distinct cellular localization of mRNAs for three subtypes of prostaglandin E receptor in kidney

1 reference

12 December 2020

Induction of cAMP-dependent protein kinase (PKA) activity in T cells after stimulation of the prostaglandin E2 or the beta-adrenergic receptors: relationship between PKA activity and inhibition of anti-CD3 monoclonal antibody-induced T cell prolifer

1 reference

12 December 2020

MEK1 and the extracellular signal-regulated kinases are required for the stimulation of IL-2 gene transcription in T cells

1 reference

12 December 2020

Differential localization of prostaglandin E receptor subtypes in human kidney

1 reference

12 December 2020

Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema

1 reference

12 December 2020

Prostaglandin E receptor EP4 antagonism inhibits breast cancer metastasis

1 reference

12 December 2020

Role of prostaglandin E2 in the induction of nonspecific T lymphocyte suppressor activity

1 reference

12 December 2020

Exogenous additions of prostaglandins variably alter the blastogenic response of B and T lymphocytes from different mice lymphoid organs

1 reference

12 December 2020

Suppression of T lymphocyte proliferation during lymphoma growth in mice: role of PGE2-producing suppressor macrophages

1 reference

12 December 2020

Lymphokine regulation of activated (G1) lymphocytes. I. Prostaglandin E2-induced inhibition of interleukin 2 production

1 reference

12 December 2020

Inhibition of lymphocyte response by prostaglandin-producing suppressor cells in patients with melanoma

1 reference

12 December 2020

The effects of prostaglandins on the proliferation of cultured human T lymphocytes

1 reference

12 December 2020

Regulation of interleukin 2 synthesis by cAMP in human T cells

1 reference

12 December 2020

Effects of anti-proliferative cyclic AMP on interleukin 2-stimulated gene expression

1 reference

12 December 2020

Cyclic AMP concentrations modulate both calcium flux and hydrolysis of phosphatidylinositol phosphates in mouse T lymphocytes

1 reference

12 December 2020

Are prostaglandins proinflammatory, antiinflammatory, both or neither?

1 reference

12 December 2020

Prostaglandin E2 and other cyclic AMP-elevating agents modulate IL-2 and IL-2R alpha gene expression at multiple levels

1 reference

12 December 2020

Two isoforms of prostaglandin E receptor EP3 subtype. Different COOH-terminal domains determine sensitivity to agonist-induced desensitization

1 reference

12 December 2020

Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes

1 reference

12 December 2020

Identifiers

DOI

10.1038/ICB.2011.75

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21946663%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21946663%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references