PI3Kγ in hypertension: a novel therapeutic target controlling vascular myogenic tone and target organ damage (Q27026365)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610309%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

PI3Kγ in hypertension: a novel therapeutic target controlling vascular myogenic tone and target organ damage (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610309%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

main subject

arterial hypertension

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610309%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Giuseppe Lembo

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610309%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

D. Carnevale

series ordinal

1

1 reference

G. Lembo

series ordinal

2

1 reference

language of work or name

1 reference

19 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610309%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

Cardiovascular Research

2 references

PubMed

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610309%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

95

2 references

PubMed

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610309%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

issue

4

2 references

PubMed

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610309%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

403-408

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610309%20AND%20SRC:MED&resulttype=core&format=json

Clinical problem-solving. Eyes wide open.

1 February 2020

cites work

1 reference

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21 January 2018

1 reference

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Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure

21 January 2018

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Hypertension in mice lacking the gene for endothelial nitric oxide synthase

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Vascular remodeling: implications for small artery function and target organ damage

21 January 2018

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Therapeutic potential of pharmacologically targeting arteriolar myogenic tone.

21 January 2018

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WNK1 regulates vasoconstriction and blood pressure response to α 1-adrenergic stimulation in mice

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Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

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1 reference

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PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism

21 January 2018

1 reference

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Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma

21 January 2018

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The phosphoinositide 3-kinase pathway

21 January 2018

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The emerging mechanisms of isoform-specific PI3K signalling

21 January 2018

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The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease

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Role of Akt signaling in vascular homeostasis and angiogenesis

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Taming the PI3K team to hold inflammation and cancer at bay.

21 January 2018

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Cardiac regulation by phosphoinositide 3-kinases and PTEN

21 January 2018

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Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes

21 January 2018

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PTEN and myotubularin: novel phosphoinositide phosphatases

21 January 2018

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The non-excitable smooth muscle: calcium signaling and phenotypic switching during vascular disease

21 January 2018

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L-type Ca2+ channels: a new player in the regulation of Ca2+ signaling, cell activation and cell survival in immune cells

21 January 2018

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Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

21 January 2018

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Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure.

21 January 2018

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PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects

21 January 2018

1 reference

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Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ.

21 January 2018

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Distinct effects of leukocyte and cardiac phosphoinositide 3-kinase γ activity in pressure overload-induced cardiac failure

21 January 2018

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Phosphoinositide 3-kinase gamma mediates angiotensin II-induced stimulation of L-type calcium channels in vascular myocytes

21 January 2018

1 reference

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Phosphoinositide 3-kinase isoforms selectively couple receptors to vascular L-type Ca(2+) channels

21 January 2018

1 reference

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Regulation of vascular L-type Ca2+ channels by phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

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PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane

21 January 2018

1 reference

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Akt regulates L-type Ca2+ channel activity by modulating Cavalpha1 protein stability.

21 January 2018

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The emerging role of Ca2+ sensitivity regulation in promoting myogenic vasoconstriction

21 January 2018

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Canonical TRP channels and mechanotransduction: from physiology to disease states.

21 January 2018

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Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury

21 January 2018

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Involvement of phosphoinositide 3-kinase gamma in angiogenesis and healing of experimental myocardial infarction in mice

21 January 2018

1 reference

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Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes

21 January 2018

1 reference

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Mechanisms of target organ damage caused by hypertension: therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS166

Nonsteroidal antiinflammatory drugs, acetaminophen, and the risk of cardiovascular events

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS166

Cardiovascular risk associated with celecoxib

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/CVR/CVS166

2 references

Consolidated OpenCitations Corpus – April 2017

3943673

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610309%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

3943673

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

3943673

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22610309%20AND%20SRC:MED&resulttype=core&format=json