Pre-Anchoring of Pin1 to Unphosphorylated c-Myc in a Fuzzy Complex Regulates c-Myc Activity. (Q27303574)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26655473%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Pre-Anchoring of Pin1 to Unphosphorylated c-Myc in a Fuzzy Complex Regulates c-Myc Activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26655473%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

0 references

Madhanagopal Anandapadamanaban

8

1 reference

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2 March 2020

S Cristobal

9

1 reference

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2 March 2020

author name string

Sara Helander

1

1 reference

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2 March 2020

Meri Montecchio

2

1 reference

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2 March 2020

Robert Pilstål

3

1 reference

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2 March 2020

Yulong Su

4

1 reference

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2 March 2020

Jacob Kuruvilla

5

1 reference

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2 March 2020

Malin Elvén

6

1 reference

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2 March 2020

Javed M E Ziauddin

7

1 reference

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2 March 2020

Patrik Lundström

10

1 reference

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2 March 2020

Rosalie C Sears

11

1 reference

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2 March 2020

Björn Wallner

12

1 reference

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2 March 2020

Maria Sunnerhagen

13

1 reference

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2 March 2020

language of work or name

English

0 references

publication date

19 November 2015

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2 March 2020

1 reference

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2 March 2020

volume

23

1 reference

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2 March 2020

page(s)

2267-2279

1 reference

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2 March 2020

issue

12

1 reference

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Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code

2 March 2020

cites work

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Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins

21 March 2017

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cis -Proline-mediated Ser(P) 5 Dephosphorylation by the RNA Polymerase II C-terminal Domain Phosphatase Ssu72

21 March 2017

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The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc

21 March 2017

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High-resolution structure prediction and the crystallographic phase problem

21 March 2017

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Structural analysis of the mitotic regulator hPin1 in solution: insights into domain architecture and substrate binding

21 March 2017

1 reference

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1H NMR study on the binding of Pin1 Trp-Trp domain with phosphothreonine peptides

21 March 2017

1 reference

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Structural basis for phosphoserine-proline recognition by group IV WW domains

21 March 2017

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The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases

21 March 2017

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Function of WW domains as phosphoserine- or phosphothreonine-binding modules

21 March 2017

1 reference

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Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent

21 March 2017

1 reference

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Pinning down proline-directed phosphorylation signaling

21 March 2017

1 reference

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c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells

21 March 2017

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Prolyl cis-trans isomerization as a molecular timer

21 March 2017

1 reference

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PINT: a software for integration of peak volumes and extraction of relaxation rates

21 March 2017

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Investigating Dynamic Interdomain Allostery in Pin1

9 May 2017

1 reference

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Two pathways mediate interdomain allosteric regulation in pin1

28 September 2017

1 reference

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Pin1: a molecular orchestrator in the heart.

28 September 2017

1 reference

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Myc and its interactors take shape.

28 September 2017

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28 September 2017

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Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions

28 September 2017

1 reference

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From sequence and forces to structure, function, and evolution of intrinsically disordered proteins

28 September 2017

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Structural changes of CFTR R region upon phosphorylation: a plastic platform for intramolecular and intermolecular interactions

28 September 2017

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Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis

28 September 2017

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Complete thermodynamic and kinetic characterization of the isomer-specific interaction between Pin1-WW domain and the amyloid precursor protein cytoplasmic tail phosphorylated at Thr668.

28 September 2017

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Transcriptional amplification in tumor cells with elevated c-Myc.

28 September 2017

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Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase

28 September 2017

1 reference

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Fuzzy complexes: a more stochastic view of protein function

28 September 2017

1 reference

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Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression

28 September 2017

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Stereospecific gating of functional motions in Pin1

28 September 2017

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Rosetta FlexPepDock ab-initio: simultaneous folding, docking and refinement of peptides onto their receptors

28 September 2017

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Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1.

28 September 2017

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Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function

28 September 2017

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Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland.

28 September 2017

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Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

28 September 2017

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Reflecting on 25 years with MYC.

28 September 2017

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Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor

28 September 2017

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On the benefit of bivalency in peptide ligand/pin1 interactions

28 September 2017

1 reference

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The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease

28 September 2017

1 reference

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Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function

28 September 2017

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Mechanism of transcriptional activation by the Myc oncoproteins

28 September 2017

1 reference

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The life cycle of C-myc: from synthesis to degradation

28 September 2017

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A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

28 September 2017

1 reference

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The c-Myc transactivation domain is a direct modulator of apoptotic versus proliferative signals

28 September 2017

1 reference

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Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.

28 September 2017

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Structure and expression of the murine L-myc gene.

28 September 2017

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Interaction of the eukaryotic initiation factor 4E with 4E-BP2 at a dynamic bipartite interface

28 September 2017

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Interdomain interactions support interdomain communication in human Pin1

31 May 2018

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Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding

31 May 2018

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Transient domain interactions enhance the affinity of the mitotic regulator Pin1 toward phosphorylated peptide ligands.

31 May 2018

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Protein-protein docking with backbone flexibility.

28 November 2018

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Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation

28 November 2018

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Peptide binding induces large scale changes in inter-domain mobility in human Pin1.

28 November 2018

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Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function

28 November 2018

1 reference

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Combined chemical shift changes and amino acid specific chemical shift mapping of protein-protein interactions

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26655473

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26655473

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Substrate recognition reduces side-chain flexibility for conserved hydrophobic residues in human Pin1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26655473

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STR.2015.10.010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26655473%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26655473%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference