The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization (Q27318794)

2

Natalie

Fisher

1 reference

19 October 2023

Harnoor Bamrah

3

Harnoor

Bamrah

1 reference

19 October 2023

Carolyn Voisey

4

Carolyn

Voisey

1 reference

19 October 2023

Joshua C Price

5

Joshua C

Price

1 reference

19 October 2023

William E Farrell

6

William E

Farrell

1 reference

19 October 2023

Charles W Redman

7

Charles W

Redman

1 reference

19 October 2023

Alan Richardson

8

Alan

Creative Commons Attribution 4.0 International

Richardson

1 reference

19 October 2023

language of work or name

English

0 references

publication date

2016

0 references

published in

PLOS One

0 references

volume

11

0 references

issue

3

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page(s)

e0150696

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copyright license

start time

7 March 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Combination of chloroquine and GX15-070 (obatoclax) results in synergistic cytotoxicity against pancreatic cancer cells

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Obatoclax induces G1/G0-phase arrest via p38/p21(waf1/Cip1) signaling pathway in human esophageal cancer cells

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Combination of AZD2281 (Olaparib) and GX15-070 (Obatoclax) results in synergistic antitumor activities in preclinical models of pancreatic cancer

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Navitoclax augments the activity of carboplatin and paclitaxel combinations in ovarian cancer cells

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Lapatinib and obatoclax kill breast cancer cells through reactive oxygen species-dependent endoplasmic reticulum stress

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Identification of dual mTORC1 and mTORC2 inhibitors in melanoma cells: prodigiosin vs. obatoclax.

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Mcl-1 and YY1 inhibition and induction of DR5 by the BH3-mimetic Obatoclax (GX15-070) contribute in the sensitization of B-NHL cells to TRAIL apoptosis

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28 September 2017

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28 September 2017

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28 September 2017

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Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine

31 May 2018

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Distinct cellular and therapeutic effects of obatoclax in rituximab-sensitive and -resistant lymphomas.

31 May 2018

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31 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0150696

The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0150696

10.1371/JOURNAL.PONE.0150696

21 January 2018

Identifiers

DOI

1 reference

4872816

ADS bibcode

2016PLoSO..1150696S

0 references

4872816

1 reference

1 reference

1 reference