A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation (Q27340503)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21625621%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation (English)

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2 February 2020

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1

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2 February 2020

Lina M. Obeid

8

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2 February 2020

7

Yusuf A Hannun

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2 February 2020

author name string

Stefka D Spassieva

2

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2 February 2020

Thomas J Jucius

3

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2 February 2020

Leonard D Shultz

4

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2 February 2020

H Elizabeth Shick

5

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2 February 2020

Wendy B Macklin

6

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2 February 2020

Susan L Ackerman

9

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2 February 2020

language of work or name

English

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publication date

19 May 2011

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2 February 2020

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2 February 2020

volume

7

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issue

5

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2 February 2020

page(s)

e1002063

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Creative Commons Attribution 4.0 International

2 February 2020

copyright license

start time

19 May 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells

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Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors

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Alterations of the sphingolipid pathway in Alzheimer's disease: new biomarkers and treatment targets?

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Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas

29 September 2017

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29 September 2017

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21 January 2018

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21 January 2018

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21 January 2018

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Sphingolipid biosynthesis is necessary for dendrite growth and survival of cerebellar Purkinje cells in culture

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21625621

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice

1 reference

PubMed

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inferred from PubMed ID database lookup

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based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1002063

2 references

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2 February 2020

1 reference

2 references

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2 February 2020

2 references