Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function (Q27648839)

Catherine A Royer

9

0 references

Hinrich Gronemeyer

Hinrich Gronemeyer

10

0 references

Angel R de Lera

Angel R de Lera

11

0 references

Pierre Germain

3

Pierre Germain

0 references

author name string

Virginie Nahoum

1

0 references

Efrén Pérez

2

0 references

Fátima Rodríguez-Barrios

4

0 references

Fabio Manzo

5

0 references

Sabrina Kammerer

6

0 references

Geraldine Lemaire

7

0 references

Oliver Hirsch

Proceedings of the National Academy of Sciences of the United States of America

8

0 references

language of work or name

English

0 references

publication date

30 October 2007

0 references

published in

0 references

volume

104

0 references

page(s)

17323-8

0 references

issue

44

0 references

cites work

Molecular recognition of agonist ligands by RXRs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

The CCP4 suite: programs for protein crystallography

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

International Union of Pharmacology. LXIII. Retinoid X receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Coregulator function: a key to understanding tissue specificity of selective receptor modulators

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Design of selective nuclear receptor modulators: RAR and RXR as a case study

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

RAR and RXR modulation in cancer and metabolic disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

A structure-based approach to retinoid X receptor-alpha inhibition.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Co-resistance to retinoic acid and TRAIL by insertion mutagenesis into RAM.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Synthetic retinoids: recent developments concerning structure and clinical utility.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Controlling nuclear receptors: the circular logic of cofactor cycles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Mechanism of the nuclear receptor molecular switch

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Synthetic retinoids and their nuclear receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Autonomous rexinoid death signaling is suppressed by converging signaling pathways in immature leukemia cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Structural studies on nuclear receptors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Activation of specific RXR heterodimers by an antagonist of RXR homodimers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Novel retinoid X receptor antagonists: specific inhibition of retinoid synergism in RXR-RAR heterodimer actions

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705356104

Determinants of retinoid X receptor transcriptional antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705356104

Novel retinoid X receptor (RXR) antagonists having a dicarba-closo-dodecaborane as a hydrophobic moiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705356104

Single-column purification of free recombinant proteins using a self-cleavable affinity tag derived from a protein splicing element

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705356104

A dynamic mechanism of nuclear receptor activation and its perturbation in a human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705356104

Rexinoid-triggered differentiation and tumor-selective apoptosis of acute myeloid leukemia by protein kinase A-mediated desubordination of retinoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705356104

Co-regulator recruitment and the mechanism of retinoic acid receptor synergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705356104

Molecular Recognition of Agonist Ligands by RXRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0705356104

A set of van der Waals and coulombic radii of protein atoms for molecular and solvent-accessible surface calculation, packing evaluation, and docking.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2077255

Recruitment of RXR by Homotetrameric RARα Fusion Proteins Is Essential for Transformation

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17947383

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

RXR is an essential component of the oncogenic PML/RARA complex in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17947383