Functional residues on the surface of the N-terminal domain of yeast Pms1 (Q27659620)

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17 January 2020

title

Functional residues on the surface of the N-terminal domain of yeast Pms1 (English)

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17 January 2020

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5

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17 January 2020

Thomas A Kunkel

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17 January 2020

author name string

Mercedes E Arana

1

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17 January 2020

Shannon F Holmes

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17 January 2020

John M Fortune

3

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17 January 2020

Andrea F Moon

4

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17 January 2020

publication date

1 April 2010

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17 January 2020

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17 January 2020

volume

9

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17 January 2020

issue

4

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17 January 2020

page(s)

448-457

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describes a project that uses

17 January 2020

ImageQuant

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11 June 2022

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Mutations affecting a putative MutLalpha endonuclease motif impact multiple mismatch repair functions

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N-terminus of hMLH1 confers interaction of hMutLalpha and hMutLbeta with hMutSalpha

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Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteins

20 March 2017

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MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp

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Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

20 March 2017

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Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae

20 March 2017

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Mouse models for human DNA mismatch-repair gene defects

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Comparative analysis of meiotic progression in female mice bearing mutations in genes of the DNA mismatch repair pathway

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Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair

29 September 2017

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Human MLH1 protein participates in genomic damage checkpoint signaling in response to DNA interstrand crosslinks, while MSH2 functions in DNA repair

29 September 2017

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A mutation in the putative MLH3 endonuclease domain confers a defect in both mismatch repair and meiosis in Saccharomyces cerevisiae

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Mismatch repair proteins, meiosis, and mice: understanding the complexities of mammalian meiosis

29 September 2017

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DNA mismatch repair: from structure to mechanism.

29 September 2017

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DNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair.

29 September 2017

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MLH1 mutations differentially affect meiotic functions in Saccharomyces cerevisiae

29 September 2017

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Systematic mutagenesis of the Saccharomyces cerevisiae MLH1 gene reveals distinct roles for Mlh1p in meiotic crossing over and in vegetative and meiotic mismatch repair

29 September 2017

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Mutations within the hMLH1 and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha

29 September 2017

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Contribution of human mlh1 and pms2 ATPase activities to DNA mismatch repair

29 September 2017

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Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae

29 September 2017

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Inactivation of DNA mismatch repair by increased expression of yeast MLH1.

29 September 2017

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DNA mismatch repair and genetic instability

29 September 2017

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Escherichia coli MutL loads DNA helicase II onto DNA.

29 September 2017

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Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations.

29 September 2017

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Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.

29 September 2017

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Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutations

29 September 2017

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Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs

29 September 2017

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Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants.

29 September 2017

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Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs

29 September 2017

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The DNA binding properties of the MutL protein isolated from Escherichia coli

29 September 2017

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Mismatch repair-dependent iterative excision at irreparable O6-methylguanine lesions in human nuclear extracts

29 September 2017

1 reference

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Msh2 separation of function mutations confer defects in the initiation steps of mismatch repair

2 June 2018

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Endonucleolytic function of MutLalpha in human mismatch repair.

2 June 2018

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[Homologs of MutS and MutL during mammalian meiosis].

27 November 2018

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In vivo site-directed mutagenesis using oligonucleotides

27 November 2018

1 reference

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Analysis of interactions between mismatch repair initiation factors and the replication processivity factor PCNA

27 November 2018

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12 December 2020

The effect of genetic background on the function of Saccharomyces cerevisiae mlh1 alleles that correspond to HNPCC missense mutations

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12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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12 December 2020

Site-directed mutations in motif VI of Escherichia coli DNA helicase II result in multiple biochemical defects: evidence for the involvement of motif VI in the coupling of ATPase and DNA binding activities via conformational changes

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12 December 2020

10.1016/J.DNAREP.2010.01.010

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20138591%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20138591%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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