NMR structure of the transmembrane domain of the n-acetylcholine receptor β2 subunit (Q27661310)

1

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Tommy Tillman

2

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Yan Xu

3

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Pei Tang

Biochimica et Biophysica Acta

4

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language of work or name

English

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publication date

August 2010

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published in

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volume

1798

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issue

8

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page(s)

1608-14

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cites work

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Structural Basis for Signal-Sequence Recognition by the Translocase Motor SecA as Determined by NMR

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Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution

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NMR Structure and Dynamics of the Second Transmembrane Domain of the Neuronal Acetylcholine Receptor β2 Subunit

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Assembly of a polytopic membrane protein structure from the solution structures of overlapping peptide fragments of bacteriorhodopsin

20 March 2017

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Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy

20 March 2017

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Protein backbone angle restraints from searching a database for chemical shift and sequence homology

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Torsion angle dynamics for NMR structure calculation with the new program DYANA

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1H, 13C and 15N chemical shift referencing in biomolecular NMR

20 March 2017

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

20 March 2017

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Nicotinic acetylcholine receptors: from structure to brain function

20 March 2017

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Refined structure of the nicotinic acetylcholine receptor at 4A resolution

20 March 2017

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Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors

20 March 2017

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Modulation of neuronal nicotinic acetylcholine receptors by halothane in rat cortical neurons

20 March 2017

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Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine

20 March 2017

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A method for efficient isotopic labeling of recombinant proteins

20 March 2017

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Higher susceptibility to halothane modulation in open- than in closed-channel alpha4beta2 nAChR revealed by molecular dynamics simulations

7 April 2017

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Structural basis of activation of cys-loop receptors: the extracellular-transmembrane interface as a coupling region

29 September 2017

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Anesthetic effects on the structure and dynamics of the second transmembrane domains of nAChR alpha4beta2

29 September 2017

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Boundary lipids in the nicotinic acetylcholine receptor microenvironment.

29 September 2017

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General anesthetic binding to neuronal alpha4beta2 nicotinic acetylcholine receptor and its effects on global dynamics

29 September 2017

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Nicotinic acetylcholine receptors at atomic resolution

29 September 2017

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Gating mechanisms in Cys-loop receptors

29 September 2017

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Pore structure of the Cys-loop ligand-gated ion channels

29 September 2017

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In silico models for the human alpha4beta2 nicotinic acetylcholine receptor

29 September 2017

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Diversity of vertebrate nicotinic acetylcholine receptors

29 September 2017

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Construction of a series of vectors for high throughput cloning and expression screening of membrane proteins from Mycobacterium tuberculosis

29 September 2017

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Modular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loop

29 September 2017

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Mechanics of channel gating of the nicotinic acetylcholine receptor

29 September 2017

1 reference

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Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity.

29 September 2017

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From interactions of single transmembrane helices to folding of alpha-helical membrane proteins: analyzing transmembrane helix-helix interactions in bacteria

29 September 2017

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Structure of the first transmembrane domain of the neuronal acetylcholine receptor beta2 subunit

29 September 2017

1 reference

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Comprehensive evaluation of solution nuclear magnetic resonance spectroscopy sample preparation for helical integral membrane proteins

29 September 2017

1 reference

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Solution NMR of membrane proteins: practice and challenges

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

HFIP-induced structures and assemblies of the peptides from the transmembrane domain 4 of membrane protein Nramp1.

29 September 2017

1 reference

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Conformation and environment of channel-forming peptides: a simulation study

29 September 2017

1 reference

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Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel.

29 September 2017

1 reference

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Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

Isoflurane modulation of neuronal nicotinic acetylcholine receptors expressed in human embryonic kidney cells.

29 September 2017

1 reference

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Homology modeling and molecular dynamics simulations of transmembrane domain structure of human neuronal nicotinic acetylcholine receptor

29 September 2017

1 reference

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Nicotinic receptors in human brain: topography and pathology

29 September 2017

1 reference

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Mutations in the M4 domain of Torpedo californica acetylcholine receptor dramatically alter ion channel function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

Site-specific mutations of nicotinic acetylcholine receptor at the lipid-protein interface dramatically alter ion channel gating

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

An intramembrane aromatic network determines pentameric assembly of Cys-loop receptors

29 September 2017

1 reference

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A lipid-dependent uncoupled conformation of the acetylcholine receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

Functional effects of periodic tryptophan substitutions in the alpha M4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

Mutations at lipid-exposed residues of the acetylcholine receptor affect its gating kinetics

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

Tryptophan substitutions at the lipid-exposed transmembrane segment M4 of Torpedo californica acetylcholine receptor govern channel gating.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

Dynamic activation of an allosteric regulatory protein.

2 June 2018

1 reference

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Position of helical kinks in membrane protein crystal structures and the accuracy of computational prediction

27 November 2018

1 reference

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Voronoia: analyzing packing in protein structures

27 November 2018

1 reference

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Charged residues in the alpha1 and beta2 pre-M1 regions involved in GABAA receptor activation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

Fluorescence and molecular dynamics studies of the acetylcholine receptor gammaM4 transmembrane peptide in reconstituted systems.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

Conformational dynamics of the nicotinic acetylcholine receptor channel: a 35-ns molecular dynamics simulation study

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

Stability of loops in the structure of lactose permease

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

Proline-induced distortions of transmembrane helices.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffected

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885491

Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis

27 November 2018

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12 December 2020

Membrane protein folding and oligomerization: the two-stage model

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12 December 2020

Slow-channel mutation in acetylcholine receptor alphaM4 domain and its efficient knockdown

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12 December 2020

Blocking of the nicotinic acetylcholine receptor ion channel by chlorpromazine, a noncompetitive inhibitor: A molecular dynamics simulation study

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12 December 2020

Dynamics of heteropentameric nicotinic acetylcholine receptor: implications of the gating mechanism

1 reference

12 December 2020