The Mechanism for Activation of GTP Hydrolysis on the Ribosome (Q27665613)

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Ann C Kelley

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object named as

Ann C Kelley

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author name string

T Martin Schmeing

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Ann C Kelley

The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA

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language of work or name

English

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publication date

5 November 2010

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published in

Science

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volume

330

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issue

6005

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page(s)

835-8

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

GTPase activation of elongation factor EF-Tu by the ribosome during decoding

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Visualization of the eEF2–80S Ribosome Transition-State Complex by Cryo-Electron Microscopy

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Recognition of cognate transfer RNA by the 30S ribosomal subunit

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Conformational change of elongation factor Tu (EF-Tu) induced by antibiotic binding. Crystal structure of the complex between EF-Tu.GDP and aurodox

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Structure of the 70S ribosome complexed with mRNA and tRNA

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

The GTPase superfamily: conserved structure and molecular mechanism

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Role of a Buried Acid Group in the Mechanism of Action of Chymotrypsin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Phylogenetic distribution of translational GTPases in bacteria

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Crystal structure of active elongation factor Tu reveals major domain rearrangements

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Ribosomal Acidic Phosphoproteins P1 and P2 Are Not Required for Cell Viability but Regulate the Pattern of Protein Expression in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Characterization of the GTPase reaction of elongation factor Tu. Determination of the stereochemical course in the presence of antibiotic X5108

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Structure-function relationships in the GTP binding domain of EF-Tu: mutation of Val20, the residue homologous to position 12 in p21

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

GTP-binding domain: three consensus sequence elements with distinct spacing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Evidence that the G2661 region of 23S rRNA is located at the ribosomal binding sites of both elongation factors.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

Effect of the antibiotic purpuromycin on cell-free protein-synthesizing systems

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763471

GTPase activation of elongation factors Tu and G on the ribosome

2 June 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1194460

The importance of structural transitions of the switch II region for the functions of elongation factor Tu on the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1194460

Mutations in 23 S ribosomal RNA perturb transfer RNA selection and can lead to streptomycin dependence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1194460

Transient conformational states of aminoacyl-tRNA during ribosome binding catalyzed by elongation factor Tu.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1194460

Synergism between the GTPase activities of EF-Tu.GTP and EF-G.GTP on empty ribosomes. Elongation factors as stimulators of the ribosomal oscillation between two conformations

21 January 2018

1 reference

12 December 2020

Interaction sites of ribosome-bound eukaryotic elongation factor 2 in 18S and 28S rRNA

1 reference

12 December 2020

Formation of a Transition-State Analog of the Ras GTPase Reaction by Ras GDP, Tetrafluoroaluminate, and GTPase-Activating Proteins

1 reference

12 December 2020

A Common Structural Motif in Elongation Factor Ts and Ribosomal Protein L7/12 May Be Involved in the Interaction with Elongation Factor Tu

1 reference

12 December 2020

Identifiers

DOI

10.1126/SCIENCE.1194460

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release_b6ljsjfdpbhypp2ixy5zvmd5pu

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Fatcat

https://api.fatcat.wiki/v0/release/b6ljsjfdpbhypp2ixy5zvmd5pu

24 November 2022

mapped directly with Wikidata item

232751

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1 reference

232751

PubMed publication ID

21051640

1 reference