Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA (Q27681187)

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13 June 2020

Ivan R Correa

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13 June 2020

author name string

June E Pais

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13 June 2020

Xing Zhang

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13 June 2020

Lana Saleh

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13 June 2020

Zheng-Qing Fu

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13 June 2020

Nan Dai

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13 June 2020

Yu Zheng

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13 June 2020

Xiaodong Cheng

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13 June 2020

language of work or name

English

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publication date

20 February 2014

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published in

Nature

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13 June 2020

volume

506

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13 June 2020

issue

7488

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13 June 2020

page(s)

391-395

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LSD2/KDM1B and Its Cofactor NPAC/GLYR1 Endow a Structural and Molecular Model for Regulation of H3K4 Demethylation

13 June 2020

cites work

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Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation

20 March 2017

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

20 March 2017

1 reference

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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

20 March 2017

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Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase

20 March 2017

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The Genome of Naegleria gruberi Illuminates Early Eukaryotic Versatility

20 March 2017

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 March 2017

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

20 March 2017

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Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA

20 March 2017

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MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

20 March 2017

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Stressing-out DNA? The contribution of serine-phosphodiester interactions in catalysis by uracil DNA glycosylase

20 March 2017

1 reference

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A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA

20 March 2017

1 reference

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HhaI methyltransferase flips its target base out of the DNA helix

20 March 2017

1 reference

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Features and development of Coot

20 March 2017

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Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

20 March 2017

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Structural studies on human 2-oxoglutarate dependent oxygenases

20 March 2017

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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

20 March 2017

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Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites

20 March 2017

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Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha

22 April 2017

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Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB

22 April 2017

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Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

22 April 2017

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Multiparametric scaling of diffraction intensities

7 April 2017

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Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA.

7 April 2017

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High-resolution enzymatic mapping of genomic 5-hydroxymethylcytosine in mouse embryonic stem cells

29 September 2017

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Role of the jelly-roll fold in substrate binding by 2-oxoglutarate oxygenases

29 September 2017

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Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.

29 September 2017

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Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development.

29 September 2017

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Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

29 September 2017

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5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging

29 September 2017

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Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.

29 September 2017

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5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells

29 September 2017

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Natural history of eukaryotic DNA methylation systems

29 September 2017

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Caught in the act: visualization of an intermediate in the DNA base-flipping pathway induced by HhaI methyltransferase

29 September 2017

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29 September 2017

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Quantification of the sixth DNA base hydroxymethylcytosine in the brain

21 January 2018

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SGXPro: a parallel workflow engine enabling optimization of program performance and automation of structure determination

21 January 2018

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The discovery of 5-formylcytosine in embryonic stem cell DNA.

21 January 2018

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Nucleic acid modifications with epigenetic significance

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/NATURE12905

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24390346%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 June 2020

1040056615

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24390346%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

24390346

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24390346%20AND%20SRC:MED&resulttype=core&format=json