Chemical arsenal for the study of O-GlcNAc. (Q27687493)

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23 January 2020

review article

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title

Chemical arsenal for the study of O-GlcNAc (English)

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23 January 2020

author name string

Eun J Kim

series ordinal

1

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23 January 2020

language of work or name

English

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publication date

28 February 2011

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23 January 2020

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23 January 2020

volume

16

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23 January 2020

issue

3

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23 January 2020

page(s)

1987-2022

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Creative Commons Attribution 4.0 International

23 January 2020

copyright license

start time

28 February 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-beta-D glucosaminidase is associated with type 2 diabetes in Mexican Americans

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12 December 2020

Enzymatic addition of O-GlcNAc to nuclear and cytoplasmic proteins. Identification of a uridine diphospho-N-acetylglucosamine:peptide beta-N-acetylglucosaminyltransferase

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12 December 2020

Identification of O-GlcNAc sites on proteins

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12 December 2020

Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

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12 December 2020

Regulation of calcium/calmodulin-dependent kinase IV by O-GlcNAc modification.

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12 December 2020

Amino acid residue specific stable isotope labeling for quantitative proteomics

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12 December 2020

Glycosylation of the c-Myc transactivation domain

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12 December 2020

Ketone isosteres of 2-N-acetamidosugars as substrates for metabolic cell surface engineering

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12 December 2020

Enrichment and site mapping of O-linked N-acetylglucosamine by a combination of chemical/enzymatic tagging, photochemical cleavage, and electron transfer dissociation mass spectrometry

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12 December 2020

O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry

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12 December 2020

Homology between O-linked GlcNAc transferases and proteins of the glycogen phosphorylase superfamily

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12 December 2020

A high-throughput assay for O-GlcNAc transferase detects primary sequence preferences in peptide substrates

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12 December 2020

Recombinant O-GlcNAc transferase isoforms: identification of O-GlcNAcase, yes tyrosine kinase, and tau as isoform-specific substrates

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12 December 2020

Biosynthesis of a nonphysiological sialic acid in different rat organs, using N-propanoyl-D-hexosamines as precursors

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12 December 2020

Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability

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12 December 2020

Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity

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12 December 2020

The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny

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12 December 2020

Purification and characterization of an O-GlcNAc selective N-acetyl-beta-D-glucosaminidase from rat spleen cytosol.

1 reference

12 December 2020

Probing the dynamics of O-GlcNAc glycosylation in the brain using quantitative proteomics

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12 December 2020

Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells

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12 December 2020

Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brain

1 reference

12 December 2020

Positive and negative regulation of insulin signaling through IRS-1 phosphorylation

1 reference

12 December 2020

Site-specific interplay between O-GlcNAcylation and phosphorylation in cellular regulation

1 reference

12 December 2020

Inactivation of phosphorylated endothelial nitric oxide synthase (Ser-1177) by O-GlcNAc in diabetes-associated erectile dysfunction

1 reference

12 December 2020

Chemical genetics: where genetics and pharmacology meet

1 reference

12 December 2020

An O-GlcNAcase-specific inhibitor and substrate engineered by the extension of the N-acetyl moiety

1 reference

12 December 2020

A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems

1 reference

12 December 2020

A chemical approach for identifying O-GlcNAc-modified proteins in cells

1 reference

12 December 2020

Elevation of Global O-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-GlcNAcase Does Not Induce Insulin Resistance

1 reference

12 December 2020

The tetratricopeptide repeat: a structural motif mediating protein-protein interactions

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12 December 2020

Structure of streptozotocin

1 reference

12 December 2020

Chemistry in living systems

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12 December 2020

Stable-isotope dimethyl labeling for quantitative proteomics

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12 December 2020

Biochemical evidence for nitric oxide formation from streptozotocin in isolated pancreatic islets

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12 December 2020

Nitric oxide generation during cellular metabolization of the diabetogenic N-methyl-N-nitroso-urea streptozotozin contributes to islet cell DNA damage.

1 reference

12 December 2020

Metabolic expression of thiol-derivatized sialic acids on the cell surface and their quantitative estimation by flow cytometry.

1 reference

12 December 2020

The protein kinase complement of the human genome

1 reference

12 December 2020

Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic beta-N-acetylglucosaminidase, O-GlcNAcase

1 reference

12 December 2020

Dynamic O-GlcNAcylation of the small heat shock protein alpha B-crystallin

1 reference

12 December 2020

Challenging estrogen receptor beta with phosphorylation

1 reference

12 December 2020

GlcNAcstatins are nanomolar inhibitors of human O -GlcNAcase inducing cellular hyper- O -GlcNAcylation

1 reference

12 December 2020

O-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress

1 reference

12 December 2020

A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout

1 reference

12 December 2020

Apoptotic cell death triggered by nitric oxide in pancreatic beta-cells

1 reference

12 December 2020

IDAWG: Metabolic incorporation of stable isotope labels for quantitative glycomics of cultured cells

1 reference

12 December 2020

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

1 reference

12 December 2020

O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic beta cells

1 reference

12 December 2020

Glycosylation of mammalian neurofilaments. Localization of multiple O-linked N-acetylglucosamine moieties on neurofilament polypeptides L and M

1 reference

12 December 2020

Characterization of the histone acetyltransferase (HAT) domain of a bifunctional protein with activable O-GlcNAcase and HAT activities

1 reference

12 December 2020

Identification of active-site inhibitors of MurG using a generalizable, high-throughput glycosyltransferase screen

1 reference

12 December 2020

Monoclonal antibodies identify a group of nuclear pore complex glycoproteins

1 reference

12 December 2020

O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.

1 reference

12 December 2020

In vivo imaging of membrane-associated glycans in developing zebrafish

1 reference

12 December 2020

Tagging-via-substrate strategy for probing O-GlcNAc modified proteins.

1 reference

12 December 2020

Parallel identification of O-GlcNAc-modified proteins from cell lysates

1 reference

12 December 2020

Characterization and dynamics of O-linked glycosylation of human cytokeratin 8 and 18.

1 reference

12 December 2020

Identification of GlcNAcylation sites of peptides and alpha-crystallin using Q-TOF mass spectrometry

1 reference

12 December 2020

Lymphocyte activation induces rapid changes in nuclear and cytoplasmic glycoproteins

1 reference

12 December 2020

Improved beta-elimination-based affinity purification strategy for enrichment of phosphopeptides

1 reference

12 December 2020

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

1 reference

12 December 2020

Identification of a nuclear variant of MGEA5, a cytoplasmic hyaluronidase and a beta-N-acetylglucosaminidase

1 reference

12 December 2020

Novel immunogenic antigen homologous to hyaluronidase in meningioma

1 reference

12 December 2020

Prolonged incubation in PUGNAc results in increased protein O-Linked glycosylation and insulin resistance in rat skeletal muscle

1 reference

12 December 2020

The effect of phosphorylation on the electron capture dissociation of peptide ions

1 reference

12 December 2020

Carbohydrate molecular weight profiling, sequence, linkage, and branching data: ES-MS and CID.

1 reference

12 December 2020

Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc–imidazole hybrid inhibitor

1 reference

12 December 2020

Characterization of beta-N-acetylglucosaminidase cleavage by caspase-3 during apoptosis

1 reference

12 December 2020

Streptozotocin inhibits O-GlcNAcase via the production of a transition state analog

1 reference

12 December 2020

Detection of O-linked N-acetylglucosamine (O-GlcNAc) on cytoplasmic and nuclear proteins

1 reference

12 December 2020

A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose

1 reference

12 December 2020

A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

1 reference

12 December 2020

Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry

1 reference

12 December 2020

Cell surface engineering by a modified Staudinger reaction

1 reference

12 December 2020

Site-specific GlcNAcylation of human erythrocyte proteins: potential biomarker(s) for diabetes

1 reference

12 December 2020

Glycosylation of nuclear and cytoplasmic proteins. Purification and characterization of a uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase

1 reference

12 December 2020

A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis

1 reference

12 December 2020

A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities

1 reference

12 December 2020

Mapping sites of O-GlcNAc modification using affinity tags for serine and threonine post-translational modifications

1 reference

12 December 2020

Akt1 is dynamically modified with O-GlcNAc following treatments with PUGNAc and insulin-like growth factor-1.

1 reference

12 December 2020

GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-glcNAcylation levels

1 reference

12 December 2020

Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha

1 reference

12 December 2020

Enzymatic characterization of O-GlcNAcase isoforms using a fluorogenic GlcNAc substrate

1 reference

12 December 2020

Comparison of metabolic abnormalities in diabetes mellitus induced by streptozotocin or by alloxan

1 reference

12 December 2020

The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha

1 reference

12 December 2020

O-GlcNAc cycling: implications for neurodegenerative disorders

1 reference

12 December 2020

Mitochondrial and nucleocytoplasmic isoforms of O-linked GlcNAc transferase encoded by a single mammalian gene

1 reference

12 December 2020

Cytoplasmic O-GlcNAc modification of the head domain and the KSP repeat motif of the neurofilament protein neurofilament-H

1 reference

12 December 2020

Streptozotocin at low doses induces apoptosis and at high doses causes necrosis in a murine pancreatic beta cell line, INS-1.

1 reference

12 December 2020

Systematic purification of five glycosidases from Streptococcus (Diplococcus) pneumoniae

1 reference

12 December 2020

Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity

1 reference

12 December 2020

A strategy to discover inhibitors of O-linked glycosylation

1 reference

12 December 2020

Structural insights into mechanism and specificity of O-GlcNAc transferase

1 reference

12 December 2020

Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents

1 reference

12 December 2020

The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin

1 reference

12 December 2020

O-GlcNAc modification is an endogenous inhibitor of the proteasome

1 reference

12 December 2020

Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability

1 reference

12 December 2020

Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

1 reference

12 December 2020

Metabolic labeling of glycans with azido sugars and subsequent glycan-profiling and visualization via Staudinger ligation

1 reference

12 December 2020

O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease

1 reference

12 December 2020

Identification of single and double sites of phosphorylation by ECD FT-ICR/MS in peptides related to the phosphorylation site domain of the myristoylated alanine-rich C kinase protein.

1 reference

12 December 2020

Identification of Asp174 and Asp175 as the key catalytic residues of human O-GlcNAcase by functional analysis of site-directed mutants

1 reference

12 December 2020

Reciprocity between O-GlcNAc and O-phosphate on the carboxyl terminal domain of RNA polymerase II.

1 reference

12 December 2020

Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc

1 reference

12 December 2020

Cloning, recombinant production, crystallization and preliminary X-ray diffraction studies of a family 84 glycoside hydrolase from Clostridium perfringens.

1 reference

12 December 2020

Glycosylation sites flank phosphorylation sites on synapsin I: O-linked N-acetylglucosamine residues are localized within domains mediating synapsin I interactions

1 reference

12 December 2020

Label-free, real-time glycosyltransferase assay based on a fluorescent artificial chemosensor

1 reference

12 December 2020

Dynamic interplay between O-linked N-acetylglucosaminylation and glycogen synthase kinase-3-dependent phosphorylation

1 reference

12 December 2020

Streptozotocin-induced beta-cell death is independent of its inhibition of O-GlcNAcase in pancreatic Min6 cells

1 reference

12 December 2020

Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity

1 reference

12 December 2020

A chemoenzymatic approach toward the rapid and sensitive detection of O-GlcNAc posttranslational modifications

1 reference

12 December 2020

Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets

1 reference

12 December 2020

Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcase.

1 reference

12 December 2020

Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats

1 reference

12 December 2020

The hexosamine signaling pathway: deciphering the "O-GlcNAc code"

1 reference

12 December 2020

Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression

1 reference

12 December 2020

A manual sequencing method for identification of phosphorylated amino acids in phosphopeptides

1 reference

12 December 2020

Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics.

1 reference

12 December 2020

Stable isotope labeling with amino acids in cell culture (SILAC) for studying dynamics of protein abundance and posttranslational modifications

1 reference

12 December 2020

Alternative O-GlcNAcylation/O-phosphorylation of Ser16 induce different conformational disturbances to the N terminus of murine estrogen receptor beta

1 reference

12 December 2020

Insulin dynamically regulates calmodulin gene expression by sequential o-glycosylation and phosphorylation of sp1 and its subcellular compartmentalization in liver cells

1 reference

12 December 2020

Discovery of O-GlcNAc transferase inhibitors

1 reference

12 December 2020

Alternative O-glycosylation/O-phosphorylation of serine-16 in murine estrogen receptor beta: post-translational regulation of turnover and transactivation activity

1 reference

12 December 2020

New amino sugar analogues are incorporated at different rates into glycoproteins of mouse organs.

1 reference

12 December 2020

Quantitative proteomics using stable isotope labeling with amino acids in cell culture

1 reference

12 December 2020

A subpopulation of estrogen receptors are modified by O-linked N-acetylglucosamine

1 reference

12 December 2020

Tandem Mass Tags: A Novel Quantification Strategy for Comparative Analysis of Complex Protein Mixtures by MS/MS

1 reference

12 December 2020

The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics

1 reference

12 December 2020

O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats

1 reference

12 December 2020

A chemical reporter strategy to probe glycoprotein fucosylation

1 reference

12 December 2020

Proteasome function is regulated by cyclic AMP-dependent protein kinase through phosphorylation of Rpt6

1 reference

12 December 2020

Selective Detection and Site-Analysis of O-GlcNAc-Modified Glycopeptides by β-Elimination and Tandem Electrospray Mass Spectrometry

1 reference

12 December 2020

Structural and sequence-based classification of glycoside hydrolases

1 reference

12 December 2020

Glycosylation of the murine estrogen receptor-alpha

1 reference

12 December 2020

Global identification of O-GlcNAc-modified proteins

1 reference

12 December 2020

Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis

1 reference

12 December 2020

Glycosyltransferases: structures, functions, and mechanisms

1 reference

12 December 2020

Quantification of post-translationally modified peptides of bovine alpha-crystallin using tandem mass tags and electron transfer dissociation

1 reference

12 December 2020

A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation

1 reference

12 December 2020

The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine

1 reference

12 December 2020

The utility of ETD mass spectrometry in proteomic analysis

1 reference

12 December 2020

Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne [3 + 2] cycloaddition

1 reference

12 December 2020

Exploring the O-GlcNAc proteome: direct identification of O-GlcNAc-modified proteins from the brain

1 reference

12 December 2020

An evolving hierarchical family classification for glycosyltransferases

1 reference

12 December 2020

O-GlcNAc cycling: emerging roles in development and epigenetics

1 reference

12 December 2020

Sperm require beta-N-acetylglucosaminidase to penetrate through the egg zona pellucida

1 reference

12 December 2020

Beta-cell apoptosis is responsible for the development of IDDM in the multiple low-dose streptozotocin model

1 reference

12 December 2020

A specific type of ganglioside as a modulator of insulin-dependent cell growth and insulin receptor tyrosine kinase activity. Possible association of ganglioside-induced inhibition of insulin receptor function and monocytic differentiation induction

1 reference

12 December 2020

Nagstatin, a new inhibitor of N-acetyl-beta-D-glucosaminidase, produced by Streptomyces amakusaensis MG846-fF3. Taxonomy, production, isolation, physico-chemical properties and biological activities

1 reference

12 December 2020

Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation

1 reference

12 December 2020

Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity

1 reference

12 December 2020

Engineering chemical reactivity on cell surfaces through oligosaccharide biosynthesis

1 reference

12 December 2020

High glucose and insulin promote O-GlcNAc modification of proteins, including alpha-tubulin

1 reference

12 December 2020

Chemical approaches to perturb, profile, and perceive glycans

1 reference

12 December 2020

Simultaneous Detection and Identification of O-GlcNAc-Modified Glycoproteins Using Liquid Chromatography−Tandem Mass Spectrometry

1 reference

12 December 2020

Regulation of the O-linked beta-N-acetylglucosamine transferase by insulin signaling.

1 reference

12 December 2020

Analysis of MGEA5 on 10q24.1-q24.3 encoding the beta-O-linked N-acetylglucosaminidase as a candidate gene for type 2 diabetes mellitus in Pima Indians

1 reference

12 December 2020

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

1 reference

12 December 2020

O-linked N-acetylglucosamine modification of insulin receptor substrate-1 occurs in close proximity to multiple SH2 domain binding motifs

1 reference

12 December 2020

O-GlcNAc regulates FoxO activation in response to glucose

1 reference

12 December 2020

Inhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 Adipocytes

1 reference

12 December 2020

Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase

1 reference

12 December 2020

Elevation of Global O-GlcNAc in rodents using a selective O-GlcNAcase inhibitor does not cause insulin resistance or perturb glucohomeostasis

1 reference

12 December 2020

Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats

1 reference

12 December 2020

Selective labeling of living cells by a photo-triggered click reaction

1 reference

12 December 2020

Hexosamine flux, the O-GlcNAc modification, and the development of insulin resistance in adipocytes

1 reference

12 December 2020

Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surfaces of intact lymphocytes. Evidence for O-linked GlcNAc

1 reference

12 December 2020

Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine

1 reference

12 December 2020

Cytosolic O-GlcNAc accumulation is not involved in beta-cell death in HIT-T15 or Min6.

1 reference

12 December 2020

Mechanism, Structure, and Inhibition of O-GlcNAc Processing Enzymes

1 reference

12 December 2020

Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis

1 reference

12 December 2020

10.3390/MOLECULES16031987

Identifiers

DOI

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23 January 2020

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23 January 2020

PubMed publication ID

2 references