YGR198w (YPP1) targets A30P alpha-synuclein to the vacuole for degradation (Q27935534)

2

0 references

Cheynita Metoyer

3

0 references

Hui Yang

4

0 references

Runhua Shi

5

0 references

Zhaojie Zhang

6

0 references

Stephan N Witt

Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity

7

0 references

language of work or name

English

0 references

publication date

18 June 2007

0 references

published in

Journal of Cell Biology

1 reference

1 December 2016

177

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page(s)

1091-104

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issue

6

0 references

cites work

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Functional specialization within a vesicle tethering complex: bypass of a subset of exocyst deletion mutants by Sec1p or Sec4p

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Exploration of essential gene functions via titratable promoter alleles

20 March 2017

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20 March 2017

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Global analysis of protein localization in budding yeast

20 March 2017

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The Ccz1-Mon1 protein complex is required for the late step of multiple vacuole delivery pathways

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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High rates of actin filament turnover in budding yeast and roles for actin in establishment and maintenance of cell polarity revealed using the actin inhibitor latrunculin-A.

20 March 2017

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The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae

20 March 2017

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end3 and end4: two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae

20 March 2017

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SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER.

20 March 2017

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20 March 2017

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A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast

20 March 2017

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Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288C

20 March 2017

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ERAD: the long road to destruction

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Tetratrico peptide repeat interactions: to TPR or not to TPR?

20 March 2017

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

20 March 2017

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Molecular Pathways of Neurodegeneration in Parkinson's Disease

7 April 2017

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Actin Assembly and Endocytosis: From Yeast to Mammals

7 April 2017

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Why are "natively unfolded" proteins unstructured under physiologic conditions?

7 April 2017

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Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles

7 April 2017

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Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae

7 April 2017

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The structure of transposable yeast mating type loci

7 April 2017

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Plasma membrane ion permeability induced by mutant alpha-synuclein contributes to the degeneration of neural cells

7 April 2017

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Spatial dynamics of receptor-mediated endocytic trafficking in budding yeast revealed by using fluorescent alpha-factor derivatives

29 September 2017

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Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiae

29 September 2017

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Alpha-synuclein targets the plasma membrane via the secretory pathway and induces toxicity in yeast

29 September 2017

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Principles of MAP kinase signaling specificity in Saccharomyces cerevisiae.

29 September 2017

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Mitochondrial fission proteins regulate programmed cell death in yeast

29 September 2017

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Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

29 September 2017

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Cytochrome c release and mitochondria involvement in programmed cell death induced by acetic acid in Saccharomyces cerevisiae

29 September 2017

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G proteins and pheromone signaling.

29 September 2017

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A pathway for targeting soluble misfolded proteins to the yeast vacuole

29 September 2017

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NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

29 September 2017

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PEP4 gene function is required for expression of several vacuolar hydrolases in Saccharomyces cerevisiae

29 September 2017

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Involvement of the late secretory pathway in actin regulation and mRNA transport in yeast.

29 September 2017

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The synthetic genetic interaction spectrum of essential genes

21 January 2018

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Heat shock prevents alpha-synuclein-induced apoptosis in a yeast model of Parkinson's disease

21 January 2018

1 reference

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Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion

21 January 2018

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Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

21 January 2018

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Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity

21 January 2018

1 reference

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Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

21 January 2018

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Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

21 January 2018

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Chromosome or chromatin condensation leads to meiosis or apoptosis in stationary yeast (Saccharomyces cerevisiae) cells.

21 January 2018

1 reference

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Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species.

21 January 2018

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The deletion of six ORFs of unknown function from Saccharomyces cerevisiae chromosome VII reveals two essential genes: YGR195w and YGR198w

27 November 2018

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PubMed

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