Phosphodiesterase-8A binds to and regulates Raf-1 kinase (Q28118406)

4 January 2017

title

Phosphodiesterase-8A binds to and regulates Raf-1 kinase (English)

1 reference

Raf-1 proto-oncogene, serine/threonine kinase

4 January 2017

main subject

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Phosphodiesterase 8A

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enzyme binding

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Phosphodiesterase 8A

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Phosphodiesterase 8 Dmel_CG45019

1 reference

Frank Christian

6

0 references

Walter Kolch

Walter Kolch

15

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Miles D. Houslay

Miles D. Houslay

16

0 references

Selim Terhzaz

Selim Terhzaz

8

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Joseph A. Beavo

12

Joseph A. Beavo

1 reference

4 January 2017

Masami Shimizu-Albergine

13

Masami Shimizu-Albergine

1 reference

4 January 2017

Kim M. Brown

1

1 reference

4 January 2017

Jon P. Day

2

1 reference

4 January 2017

Elaine Huston

3

1 reference

4 January 2017

Bastian Zimmermann

4

1 reference

4 January 2017

Kornelia Hampel

5

1 reference

4 January 2017

David Romano

7

1 reference

4 January 2017

Louisa C. Y. Lee

9

1 reference

4 January 2017

Miranda J. Willis

10

1 reference

4 January 2017

David B. Morton

11

1 reference

4 January 2017

Shireen A. Davies

14

1 reference

4 January 2017

George S. Baillie

17

1 reference

4 January 2017

language of work or name

English

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publication date

16 April 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 January 2017

published in

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4 January 2017

volume

110

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4 January 2017

issue

16

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4 January 2017

page(s)

E1533–1542

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Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

4 January 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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Kinetic and Structural Studies of Phosphodiesterase-8A and Implication on the Inhibitor Selectivity † ‡

20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

20 March 2017

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7 April 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Phosphodiesterase 8A (PDE8A) regulates excitation-contraction coupling in ventricular myocytes

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Increasing cAMP attenuates activation of mitogen-activated protein kinase

29 September 2017

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29 September 2017

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29 September 2017

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Cyclic AMP phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a vascular endothelial cadherin (VE-Cad)-based signaling complex and controls cAMP-mediated vascular permeability

29 September 2017

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Dynamic Monitoring of Cellular Remodeling Induced by the Transforming Growth Factor-β1.

2 June 2018

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In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region

2 June 2018

1 reference

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Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631629

Mechanism of inhibition of Raf-1 by protein kinase A.

2 June 2018

1 reference

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Inhibition by cAMP of Ras-dependent activation of Raf.

2 June 2018

1 reference

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Phosphodiesterase 8 (PDE8) regulates chemotaxis of activated lymphocytes

2 June 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1303004110

Loss in oxidative stress tolerance with aging linked to reduced extracellular signal-regulated kinase and Akt kinase activities

21 January 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1303004110

21 January 2018

Identifiers

DOI

10.1073/PNAS.1303004110

1 reference

ADS bibcode

2013PNAS..110E1533B

0 references

1 reference

1 reference

1 reference