Ku, a DNA repair protein with multiple cellular functions? (Q28137885)

Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap

Europe PubMed Central

title

Ku, a DNA repair protein with multiple cellular functions? (English)

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C Featherstone

1

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author name string

S P Jackson

series ordinal

2

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language of work or name

English

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publication date

14 May 1999

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published in

Mutation Research

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volume

434

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issue

1

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page(s)

3-15

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

DNA looping by Ku and the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Productive and nonproductive complexes of Ku and DNA-dependent protein kinase at DNA termini

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

DNA damage and the DNA-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Molecular and biochemical characterization of xrs mutants defective in Ku80.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Molecular and biochemical characterization of new X-ray-sensitive hamster cell mutants defective in Ku80.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

XR-C1, a new CHO cell mutant which is defective in DNA-PKcs, is impaired in both V(D)J coding and signal joint formation

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Mammalian mutants defective in the response to ionizing radiation-induced DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Ku70: a candidate tumor suppressor gene for murine T cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

The SCID mouse mutant: definition, characterization, and potential uses

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

DNA end-joining: from yeast to man

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Molecular mechanisms of DNA double strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Requirement for end-joining and checkpoint functions, but not RAD52-mediated recombination, after EcoRI endonuclease cleavage of Saccharomyces cerevisiae DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Involvement of the Saccharomyces cerevisiae HDF1 gene in DNA double-strand break repair and recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

HDF2, the second subunit of the Ku homologue from Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Structural and functional similarities between the SbcCD proteins of Escherichia coli and the RAD50 and MRE11 (RAD32) recombination and repair proteins of yeast.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

The sbcC and sbcD genes of Escherichia coli encode a nuclease involved in palindrome inviability and genetic recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

DNA repair: The Nijmegen breakage syndrome protein

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Analysis of the mechanism of interaction of simian Ku protein with DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Functional properties of the separate subunits of human DNA helicase II/Ku autoantigen

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Homologous, homeologous, and illegitimate repair of double-strand breaks during transformation of a wild-type strain and a rad52 mutant strain of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

The DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Requirements for p53 and the ATM gene product in the regulation of G1/S and S phase checkpoints.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

ATM associates with and phosphorylates p53: mapping the region of interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

1 reference

7 January 2021

A role for ATR in the DNA damage-induced phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Double strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Yeast cell-type regulation of DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Sequence-specific DNA binding by Ku autoantigen and its effects on transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

DNA-dependent protein kinase: a potent inhibitor of transcription by RNA polymerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

DNA-dependent protein kinase specifically represses promoter-directed transcription initiation by RNA polymerase I.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

A constitutive heat shock element-binding factor is immunologically identical to the Ku autoantigen

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Suppression of heat-induced hsp70 expression by the 70-kDa subunit of the human Ku autoantigen

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Stimulation of the DNA-dependent protein kinase by RNA polymerase II transcriptional activator proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Heat shock transcription factor 1 binds selectively in vitro to Ku protein and the catalytic subunit of the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Yeast Ku as a regulator of chromosomal DNA end structure

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Telomere maintenance is dependent on activities required for end repair of double-strand breaks.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Molecular model for telomeric heterochromatin in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Immunolocalization of Ku-proteins (p80/p70): localization of p70 to nucleoli and periphery of both interphase nuclei and metaphase chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2899%2900006-3

7 January 2021

10.1016/S0921-8777(99)00006-3

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

4325441

4325441

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference