Basic fibroblast growth factor stimulates activation of Rac1 through a p85 betaPIX phosphorylation-dependent pathway (Q28209505)

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20 December 2019

title

Basic fibroblast growth factor stimulates activation of Rac1 through a p85 betaPIX phosphorylation-dependent pathway (English)

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20 December 2019

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8

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20 December 2019

author name string

Eun-Young Shin

1

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20 December 2019

Kyung-Nam Woo

2

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20 December 2019

Chan-Soo Lee

3

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20 December 2019

Seong-Hoe Koo

4

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20 December 2019

Young Gyu Kim

5

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20 December 2019

Won-Jai Kim

6

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20 December 2019

Chang-Dae Bae

7

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20 December 2019

Eung-Gook Kim

9

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20 December 2019

language of work or name

English

0 references

publication date

13 October 2003

1 reference

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Journal of Biological Chemistry

20 December 2019

published in

1 reference

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20 December 2019

volume

279

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20 December 2019

issue

3

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20 December 2019

page(s)

1994-2004

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Rho GTPases and the actin cytoskeleton

20 December 2019

cites work

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Rho GTPases in neuronal morphogenesis

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Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

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Dbl family guanine nucleotide exchange factors

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Signaling to the Rho GTPases: networking with the DH domain

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PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

21 January 2018

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Phosphorylation of p85 beta PIX, a Rac/Cdc42-specific guanine nucleotide exchange factor, via the Ras/ERK/PAK2 pathway is required for basic fibroblast growth factor-induced neurite outgrowth

21 January 2018

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A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins

21 January 2018

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Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling

21 January 2018

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p95-APP1 links membrane transport to Rac-mediated reorganization of actin.

21 January 2018

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Leucine zipper-mediated homodimerization of the p21-activated kinase-interacting factor, beta Pix. Implication for a role in cytoskeletal reorganization

21 January 2018

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Structure and mutagenesis of the Dbl homology domain

21 January 2018

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Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway

21 January 2018

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Regulation of neutrophil function by Rac GTPases

21 January 2018

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Manipulation of EphB2 regulatory motifs and SH2 binding sites switches MAPK signaling and biological activity

21 January 2018

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Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization

21 January 2018

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A novel regulator of p21-activated kinases

21 January 2018

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Translocation of the Rac1 guanine nucleotide exchange factor Tiam1 induced by platelet-derived growth factor and lysophosphatidic acid

21 January 2018

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Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

21 January 2018

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Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation

21 January 2018

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

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Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

21 January 2018

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alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase

21 January 2018

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Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

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Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

21 January 2018

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Macrophage/microglia-specific protein Iba1 enhances membrane ruffling and Rac activation via phospholipase C-gamma -dependent pathway

21 January 2018

1 reference

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Platelet-derived growth factor induces the beta-gamma-secretase-mediated cleavage of Alzheimer's amyloid precursor protein through a Src-Rac-dependent pathway.

21 January 2018

1 reference

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Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential

21 January 2018

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Identification of potential mechanisms for regulation of p115 RhoGEF through analysis of endogenous and mutant forms of the exchange factor

21 January 2018

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Activation of the Lbc Rho exchange factor proto-oncogene by truncation of an extended C terminus that regulates transformation and targeting

21 January 2018

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Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

21 January 2018

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Lck regulates Vav activation of members of the Rho family of GTPases

21 January 2018

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Tyrosine phosphorylation mediates both activation and downmodulation of the biological activity of Vav

21 January 2018

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Rac activation induces NADPH oxidase activity in transgenic COSphox cells, and the level of superoxide production is exchange factor-dependent.

21 January 2018

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Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

21 January 2018

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21 January 2018

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Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

21 January 2018

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Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling

21 January 2018

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Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M307330200

2 references

Consolidated OpenCitations Corpus – April 2017

5067373

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20 December 2019

5067373

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

5067373