Terminal deoxynucleotidyl transferase: the story of a misguided DNA polymerase (Q28251730)

Biochimica et Biophysica Acta

Europe PubMed Central

title

Terminal deoxynucleotidyl transferase: the story of a misguided DNA polymerase (English)

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Edward A Motea

1

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Anthony J Berdis

series ordinal

2

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language of work or name

English

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publication date

May 2010

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published in

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volume

1804

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issue

5

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page(s)

1151-66

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cites work

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Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta

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Nonoverlapping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo

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THE EVOLUTION OF ADAPTIVE IMMUNITY

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Direct binding of TReP-132 with TdT results in reduction of TdT activity

20 March 2017

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Rev1 employs a novel mechanism of DNA synthesis using a protein template

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A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining

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Incorporation of non-nucleoside triphosphate analogues opposite to an abasic site by human DNA polymerases beta and lambda.

20 March 2017

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DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A

20 March 2017

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Distinct and opposite activities of human terminal deoxynucleotidyltransferase splice variants

20 March 2017

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Distinct requirements for Ku in N nucleotide addition at V(D)J- and non-V(D)J-generated double-strand breaks

20 March 2017

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Immunoglobulin kappa light chain gene rearrangement is impaired in mice deficient for DNA polymerase mu

20 March 2017

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Terminal deoxynucleotidyltransferase forms a ternary complex with a novel chromatin remodeling protein with 82 kDa and core histone

20 March 2017

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Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair

20 March 2017

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Innate immune recognition

20 March 2017

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Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase

20 March 2017

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Terminal deoxynucleotidyltransferase is negatively regulated by direct interaction with proliferating cell nuclear antigen

20 March 2017

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Terminal deoxynucleotidyltransferase directly interacts with a novel nuclear protein that is homologous to p65

20 March 2017

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Terminal deoxynucleotidyl transferase and repertoire development

20 March 2017

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Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotidyl transferase-positive (TdT+) leukemic cells

29 September 2017

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Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal

20 March 2017

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Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism

20 March 2017

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Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity

20 March 2017

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A general two-metal-ion mechanism for catalytic RNA

20 March 2017

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Mutational analysis of residues in the nucleotide binding domain of human terminal deoxynucleotidyl transferase

20 March 2017

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Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism

20 March 2017

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Mutagenesis by apurinic/apyrimidinic sites

20 March 2017

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Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinase

20 March 2017

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Expression of human terminal deoxynucleotidyl transferase in Escherichia coli

20 March 2017

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EVOLUTION OF THE IMMUNE RESPONSE. I. THE PHYLOGENETIC DEVELOPMENT OF ADAPTIVE IMMUNOLOGIC RESPONSIVENESS IN VERTEBRATES

20 March 2017

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Distinct and opposite diversifying activities of terminal transferase splice variants

20 March 2017

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Differential splicing in mouse thymus generates two forms of terminal deoxynucleotidyl transferase

20 March 2017

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DNA polymerases: structural diversity and common mechanisms

20 March 2017

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Distribution and roles of X-family DNA polymerases in eukaryotes

7 April 2017

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Mechanism and dynamics of translesion DNA synthesis catalyzed by the Escherichia coli Klenow fragment

29 September 2017

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BRCT domains: phosphopeptide binding and signaling modules

29 September 2017

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Shaping and reshaping CD8+ T-cell memory.

29 September 2017

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Effector and memory CTL differentiation

29 September 2017

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Energy analysis of chemistry for correct insertion by DNA polymerase beta

29 September 2017

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Biochemical, structural, and physiological characterization of terminal deoxynucleotidyl transferase

29 September 2017

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Diketo hexenoic acid derivatives are novel selective non-nucleoside inhibitors of mammalian terminal deoxynucleotidyl transferases, with potent cytotoxic effect against leukemic cells

29 September 2017

1 reference

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Isoforms of terminal deoxynucleotidyltransferase: developmental aspects and function

29 September 2017

1 reference

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A closed conformation for the Pol lambda catalytic cycle.

29 September 2017

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The DNA-polymerase-X family: controllers of DNA quality?

29 September 2017

1 reference

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Role of base stacking and sequence context in the inhibition of yeast DNA polymerase eta by pyrene nucleotide.

29 September 2017

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Generation and maintenance of immunological memory

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Interplay of natural killer cells and their receptors with the adaptive immune response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

The synthesis of peptides and proteins containing non-natural amino acids.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

29 September 2017

1 reference

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Inferences, questions and possibilities in Toll-like receptor signalling

29 September 2017

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Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mg2+.

29 September 2017

1 reference

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Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site

29 September 2017

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29 September 2017

Calf thymus polymerase.

1 reference

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The diverse spectrum of sliding clamp interacting proteins

29 September 2017

1 reference

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Flow cytometric methods for detection and quantification of apoptosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

T cell immunity in lymphoid and non-lymphoid tissues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Active site tightness and substrate fit in DNA replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Effector and memory T-cell differentiation: implications for vaccine development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Most alpha/beta T cell receptor diversity is due to terminal deoxynucleotidyl transferase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Purine and pyrimidine nucleoside analogs.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

The RAG proteins in V(D)J recombination: more than just a nuclease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Preferential localization of effector memory cells in nonlymphoid tissue

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

DNA polymerase mu, a candidate hypermutase?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Transcription, beta-like DNA polymerases and hypermutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Terminal deoxynucleotidyl transferase. catalysis of DNA (oligodeoxynucleotide) phosphorylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Terminal deoxynucleotidyl transferase catalyzes the reaction of DNA phosphorylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Stereochemical control of DNA biosynthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Selecting and maintaining a diverse T-cell repertoire

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Modulation of terminal deoxynucleotidyltransferase activity by the DNA-dependent protein kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Massive expansion of antigen-specific CD8+ T cells during an acute virus infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Biochemical basis of DNA replication fidelity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Compilation, alignment, and phylogenetic relationships of DNA polymerases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Mice lacking TdT: mature animals with an immature lymphocyte repertoire

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Influence of 5'-nearest neighbors on the insertion kinetics of the fluorescent nucleotide analog 2-aminopurine by Klenow fragment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Multi-stage proofreading in DNA replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Conformational coupling in DNA polymerase fidelity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Terminal deoxynucleotidil transferase is a nuclear PKC substrate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

The two isoforms of mouse terminal deoxynucleotidyl transferase differ in both the ability to add N regions and subcellular localization.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Stereochemical course of the 3'----5'-exonuclease activity of DNA polymerase I.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Deoxynucleotide-Polymerizing Enzymes of Calf Thymus Gland, IV. Inhibition of Terminal Deoxynucleotidyl Transferase by Metal Ligands

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Terminal Deoxyribonucleotidyl Transferase in Human Leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Isolation and characterization of bovine and mouse terminal deoxynucleotidyltransferase cDNAs expressible in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Increased frequency of N-region insertion in a murine pre-B-cell line infected with a terminal deoxynucleotidyl transferase retroviral expression vector

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Rearrangements of DNA mediated by terminal transferase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Novel non-templated nucleotide addition reactions catalyzed by procaryotic and eucaryotic DNA polymerases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

A rapid test for V(D)J recombinase activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Multiple roles of divalent cation in the terminal deoxynucleotidyltransferase reaction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

The 'A rule' of mutagen specificity: a consequence of DNA polymerase bypass of non-instructional lesions?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Fidelity mechanisms in DNA replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Comparison of D, JH, and junctional diversity in the fetal, adult, and aged B cell repertoires

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

V(D)J recombination: molecular biology and regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Terminal deoxynucleotidyl transferase as a hematopoietic cell marker

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

A study of the mechanism of DNA polymerase I from Escherichia coli with diastereomeric phosphorothioate analogs of deoxyadenosine triphosphate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Terminal deoxynucleotidyl transferase in the diagnosis of leukemia and malignant lymphoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Terminal deoxynucleotidyl-transferase levels and membrane phenotypes in diagnosis of acute leukaemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Evidence that the long murine terminal deoxynucleotidyltransferase isoform plays no role in the control of V(D)J junctional diversity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Translesional synthesis on DNA templates containing a single abasic site. A mechanistic study of the "A rule".

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Interdependence of N nucleotide addition and recombination site choice in V(D)J rearrangement.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Kinetic analysis of nucleotide incorporation and misincorporation by Klenow fragment of Escherichia coli DNA polymerase I.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Deoxynucleotide-polymerizing enzymes of calf thymus gland. VII. Replication of homopolymers.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Expression and processing of recombinant human terminal transferase in the baculovirus system.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Deoxynucleotide-polymerizing enzymes of calf thymus gland. V. Homogeneous terminal deoxynucleotidyl transferase.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Enhancing the "A-rule" of translesion DNA synthesis: promutagenic DNA synthesis using modified nucleoside triphosphates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Optimization of non-natural nucleotides for selective incorporation opposite damaged DNA.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

The use of non-natural nucleotides to probe template-independent DNA synthesis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Using 2-aminopurine fluorescence to detect bacteriophage T4 DNA polymerase-DNA complexes that are important for primer extension and proofreading reactions.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Monitoring the timing of ATP hydrolysis with activation of peptide cleavage in Escherichia coli Lon by transient kinetics

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Human DNA polymerases lambda and beta show different efficiencies of translesion DNA synthesis past abasic sites and alternative mechanisms for frameshift generation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Terminal deoxynucleotidyl transferase is down-regulated by AP-1-like regulatory elements in human lymphoid cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Evaluating the contribution of base stacking during translesion DNA replication

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Maintenance of species identity and controlling speciation of bacteria: a new function for restriction/modification systems?

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Not "molecular patterns" but molecules

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Use of 2-aminopurine and tryptophan fluorescence as probes in kinetic analyses of DNA polymerase beta

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Programmed contraction of CD8(+) T cells after infection.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Dynamics of translesion DNA synthesis catalyzed by the bacteriophage T4 exonuclease-deficient DNA polymerase

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Increased junctional diversity in fetal B cells results in a loss of protective anti-phosphorylcholine antibodies in adult mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

In vitro selection of sequence contexts which enhance bypass of abasic sites and tetrahydrofuran by T4 DNA polymerase holoenzyme.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Alternative splicing of bovine terminal deoxynucleotidyl transferase cDNA.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Novel blunt-end addition reactions catalyzed by DNA polymerase I of Escherichia coli.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846215

Thermal conversion of nonpriming deoxyribonucleic acid to primer

27 November 2018

1 reference

12 December 2020

Terminal deoxynucleotidyltransferase of 60,000 daltons from mouse, rat, and calf thymus. Purification by immunoadsorbent chromatography and comparison of peptide structures

1 reference

12 December 2020

Enzymic synthesis of polynucleotides. Oligodeoxynucleotides with one 3'-terminal ribonucleotide as primers for polydeoxynucleotide synthesis

1 reference

12 December 2020

Phosphorylation of terminal deoxynucleotidyl transferase in leukemic cells

1 reference

12 December 2020

Is terminal deoxynucleotidyl transferase a somatic mutagen in lymphocytes?

1 reference

12 December 2020

De novo DNA synthesis by human DNA polymerase lambda, DNA polymerase mu and terminal deoxyribonucleotidyl transferase

1 reference

12 December 2020

Interactions of photoactive DNAs with terminal deoxynucleotidyl transferase: identification of peptides in the DNA binding domain

1 reference

12 December 2020

Proteolytic degradation of calf thymus terminal deoxynucleotidyl transferase

1 reference

12 December 2020

Selective killing of leukemia cells by inhibition of TdT

1 reference

12 December 2020

Evaluating the contributions of desolvation and base-stacking during translesion DNA synthesis

1 reference

12 December 2020

Mechanism of DNA Strand Transfer Reactions Catalyzed by HIV-1 Reverse Transcriptase

1 reference

12 December 2020

2',3'-Dideoxyadenosine is selectively toxic for TdT-positive cells

1 reference

12 December 2020

Comparison of the Two Murine Deoxynucleotidyltransferase Terminal Isoforms

1 reference

12 December 2020

Inhibitory effects of various 2',3'-dideoxynucleoside 5'-triphosphates on the utilization of 2'-deoxynucleoside 5'-triphosphates by terminal deoxynucleotidyltransferase from calf thymus

1 reference

12 December 2020

Cyclic AMP-dependent phosphorylation of terminal deoxynucleotidyl transferase

1 reference

12 December 2020

Chemically Defined Templates and Initiators for Deoxypolynucleotide Synthesis

1 reference

12 December 2020

Biochemistry of terminal deoxynucleotidyltransferase: mechanism of inhibition by adenosine 5'-triphosphate

1 reference

12 December 2020

Limited proteolysis of calf thymus terminal deoxynucleotidyl transferase

1 reference

12 December 2020

Biochemical properties of purified human terminal deoxynucleotidyltransferase

1 reference

12 December 2020

Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays

1 reference

12 December 2020

High-level expression of murine terminal deoxynucleotidyl transferase inEscherichia coli grown at low temperature and overexpressingargU tRNA

1 reference

12 December 2020

Biochemistry of terminal deoxynucleotidyltransferase. Identification and unity of ribo- and deoxyribonucleoside triphosphate binding site in terminal deoxynucleotidyltransferase

1 reference

12 December 2020

Acute lymphoblastic leukaemia associated antigen. III ALterations in expression during treatment and in relapse

1 reference

12 December 2020

Deoxynucleotide-polymerizing enzymes of calf thymus gland. II. Properties of the terminal deoxynucleotidyltransferase

1 reference

12 December 2020

Biological pattern of AML-M0 versus AML-M1: response

1 reference

12 December 2020

Mechanisms of hydrolysis of phosphate ester derivatives of phosphoenolpyruvic acid

1 reference

12 December 2020

Synthesis of compositionally unique DNA by terminal deoxynucleotidyl transferase

1 reference

12 December 2020

Characterization of seven basic endochitinases isolated from cell cultures of Citrus sinensis (L.).

1 reference

12 December 2020

Immunological detection of a conserved structure for terminal deoxynucleotidyltransferase

1 reference

12 December 2020