Lck-dependent Fyn activation requires C terminus-dependent targeting of kinase-active Lck to lipid rafts (Q28288732)

1

0 references

Behrouz Moemeni

2

0 references

Alessandra Ferzoco

3

0 references

Kirishanthy Kathirkamathamby

4

0 references

Jenny Zhang

5

0 references

Ondrej Ballek

6

0 references

Dominique Davidson

7

0 references

Michael Julius

Journal of Biological Chemistry

9

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language of work or name

English

0 references

publication date

26 September 2008

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published in

0 references

volume

283

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issue

39

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page(s)

26409-22

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cites work

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CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling

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Palmitoylation of ligands, receptors, and intracellular signaling molecules

29 September 2017

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29 September 2017

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Characterization of the in vivo sites of serine phosphorylation on Lck identifying serine 59 as a site of mitotic phosphorylation

29 September 2017

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The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl

29 September 2017

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29 September 2017

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TCR alpha beta-independent CD28 signaling and costimulation require non-CD4-associated Lck.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATP

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Mutation of a site of tyrosine phosphorylation in the lymphocyte-specific tyrosine protein kinase, p56lck, reveals its oncogenic potential in fibroblasts

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Neither arginine nor histidine can carry out the function of lysine-295 in the ATP-binding site of p60src

29 September 2017

1 reference

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Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor

29 September 2017

1 reference

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Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

29 September 2017

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p59fyn tyrosine kinase associates with multiple T-cell receptor subunits through its unique amino-terminal domain

29 September 2017

1 reference

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Structural requirements for enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck

29 September 2017

1 reference

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29 September 2017

1 reference

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Functional characterization and conformational analysis of the Herpesvirus saimiri Tip-C484 protein

29 September 2017

1 reference

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In silico activation of Src tyrosine kinase reveals the molecular basis for intramolecular autophosphorylation

2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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Inter- and intramolecular interactions of highly purified Rous sarcoma virus-transforming protein, pp60v-src.

2 June 2018

1 reference

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Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain

2 June 2018

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2 June 2018

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Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors

2 June 2018

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Insulin-specific T cell hybridomas derived from (H-2b x H-2k)F1 mice preferably employ F1-unique restriction elements for antigen recognition

2 June 2018

1 reference

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Activation of p56lck through mutation of a regulatory carboxy-terminal tyrosine residue requires intact sites of autophosphorylation and myristylation

2 June 2018

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Association of tyrosine kinase p56lck with CD4 inhibits the induction of growth through the alpha beta T-cell receptor

2 June 2018

1 reference

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Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids.

2 June 2018

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The roles of CD8 in cytotoxic T lymphocyte function

21 January 2018

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Enrichment of lck in lipid rafts regulates colocalized fyn activation and the initiation of proximal signals through TCR alpha beta

21 January 2018

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Regulation of Lck activity by CD4 and CD28 in the immunological synapse

21 January 2018

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Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

21 January 2018

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Differential impact of intracellular carboxyl terminal domains on lipid raft localization of the murine gonadotropin-releasing hormone receptor.

21 January 2018

1 reference

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Physical association of CD4 and CD45 in primary, resting CD4+ T cells.

21 January 2018

1 reference

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Multiple determinants for rapid agonist-induced internalization of a nonmammalian gonadotropin-releasing hormone receptor: a putative palmitoylation site and threonine doublet within the carboxyl-terminal tail Are critical

21 January 2018

1 reference

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Long-Term Survival But Impaired Homeostatic Proliferation of Naive T Cells in the Absence of p56lck

21 January 2018

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Detergent resistance as a tool in membrane research

21 January 2018

1 reference

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Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56 lck

21 January 2018

1 reference

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Distinct roles for CD4 and CD8 as co-receptors in T cell receptor signalling

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18660530

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Detection of a physical and functional interaction between Csk and Lck which involves the SH2 domain of Csk and is mediated by autophosphorylation of Lck on tyrosine 394

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18660530

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

T cell costimulation by chemokine receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18660530