Retroviral restriction by APOBEC proteins (Q28290721)

Nature Reviews Immunology

Europe PubMed Central

title

Retroviral restriction by APOBEC proteins (English)

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1

Reuben S Harris

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author name string

Mark T Liddament

series ordinal

2

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language of work or name

English

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publication date

November 2004

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published in

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volume

4

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page(s)

868-77

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issue

11

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cites work

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An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22

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AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

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DNA deamination mediates innate immunity to retroviral infection

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Hypermutation of HIV-1 DNA in the Absence of the Vif Protein

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Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

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The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA

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The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1

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Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site

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Escherichia coli cytidine deaminase provides a molecular model for ApoB RNA editing and a mechanism for RNA substrate recognition

21 April 2017

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HIV-1 Vif Blocks the Antiviral Activity of APOBEC3G by Impairing Both Its Translation and Intracellular Stability

21 April 2017

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Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex

21 April 2017

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Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.

21 April 2017

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Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif

21 April 2017

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Cytidine deamination of retroviral DNA by diverse APOBEC proteins

21 April 2017

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A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins

21 April 2017

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Human APOBEC3F is another host factor that blocks human immunodeficiency virus type 1 replication

21 April 2017

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Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

21 April 2017

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A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion

21 April 2017

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APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo

21 April 2017

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Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene

21 April 2017

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Assignment of the gene encoding the human apolipoprotein B mRNA editing enzyme (APOBEC1) to chromosome 12p13.1

21 April 2017

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APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene family

21 April 2017

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Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

21 April 2017

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Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business

21 April 2017

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Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G

21 April 2017

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Complete phenotypic characterization of apobec-1 knockout mice with a wild-type genetic background and a human apolipoprotein B transgenic background, and restoration of apolipoprotein B mRNA editing by somatic gene transfer of Apobec-1

21 April 2017

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Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

21 April 2017

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Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

21 April 2017

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Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

21 April 2017

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Transcription-targeted DNA deamination by the AID antibody diversification enzyme

21 April 2017

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Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

21 April 2017

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Quality control by DNA repair

21 April 2017

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AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

21 April 2017

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RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA

21 April 2017

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In Vitro Deamination of Cytosine to Uracil in Single-stranded DNA by Apolipoprotein B Editing Complex Catalytic Subunit 1 (APOBEC1)

21 April 2017

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Lethal mutagenesis of HIV with mutagenic nucleoside analogs

21 April 2017

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DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses

21 April 2017

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Psoriasis upregulated phorbolin-1 shares structural but not functional similarity to the mRNA-editing protein apobec-1

21 April 2017

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

21 April 2017

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Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome

21 April 2017

1 reference

HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation

21 April 2017

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The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif

21 April 2017

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Nothing in Biology Makes Sense except in the Light of Evolution

21 April 2017

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AID: how does it aid antibody diversity?

31 March 2020

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Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

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Molecular cloning of an apolipoprotein B messenger RNA editing protein

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RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators

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Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: substitutions, frameshifts, and hypermutations

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Human immunodeficiency virus type 1 DNA sequences genetically damaged by hypermutation are often abundant in patient peripheral blood mononuclear cells and may be generated during near-simultaneous infection and activation of CD4(+) T cells

31 March 2020

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Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo

31 March 2020

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Cytidine deaminase. The 2.3 A crystal structure of an enzyme: transition-state analog complex

31 March 2020

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The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity.

31 March 2020

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apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, is a novel RNA-binding protein

31 March 2020

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AID mutant analyses indicate requirement for class-switch-specific cofactors

31 March 2020

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Human apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is incorporated into HIV-1 virions through interactions with viral and nonviral RNAs.

31 March 2020

1 reference

APOBEC3G is incorporated into virus-like particles by a direct interaction with HIV-1 Gag nucleocapsid protein

31 March 2020

1 reference

The interaction between HIV-1 Gag and APOBEC3G.

31 March 2020

1 reference

Functional domains of APOBEC3G required for antiviral activity

31 March 2020

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APOBEC3G targets specific virus species.

31 March 2020

1 reference

The Vif Protein of HIV Triggers Degradation of the Human Antiretroviral DNA Deaminase APOBEC3G

31 March 2020

1 reference

The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity

31 March 2020

1 reference

A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor

31 March 2020

1 reference

A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to Vif action

31 March 2020

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A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif).

31 March 2020

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Recent insights into HIV-1 Vif.

31 March 2020

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31 March 2020

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31 March 2020

Death and the retrovirus

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Comment on "Inhibition of hepatitis B virus replication by APOBEC3G".

31 March 2020

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Inhibition of hepatitis B virus replication by APOBEC3G.

31 March 2020

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ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing

31 March 2020

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Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

31 March 2020

1 reference

APOBEC-mediated editing of viral RNA.

31 March 2020

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Rapid evolution of primate antiviral enzyme APOBEC3G.

31 March 2020

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AID is essential for immunoglobulin V gene conversion in a cultured B cell line

31 March 2020

1 reference

Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

31 March 2020

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Cloning and expression of the AID gene in the channel catfish

31 March 2020

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DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine

31 March 2020

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AID mediates hypermutation by deaminating single stranded DNA.

31 March 2020

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Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

31 March 2020

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Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

31 March 2020

1 reference

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

31 March 2020

1 reference

Immunoglobulin gene conversion in chicken DT40 cells largely proceeds through an abasic site intermediate generated by excision of the uracil produced by AID-mediated deoxycytidine deamination.

31 March 2020

1 reference

Post-replication repair in DT40 cells: translesion polymerases versus recombinases

31 March 2020

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Cutting edge: DNA polymerases mu and lambda are dispensable for Ig gene hypermutation

31 March 2020

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Delineation of the role of the Mre11 complex in class switch recombination.

31 March 2020

1 reference

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

31 March 2020

1 reference

RIP: the evolutionary cost of genome defense

31 March 2020

1 reference

Molecular mechanisms of apolipoprotein B mRNA editing

31 March 2020

1 reference

Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals

31 March 2020

1 reference

Hyperediting of multiple cytidines of apolipoprotein B mRNA by APOBEC-1 requires auxiliary protein(s) but not a mooring sequence motif

31 March 2020

1 reference

Enzymatic cytosine deamination: friend and foe.

31 March 2020

1 reference

Constitutive expression of AID leads to tumorigenesis

31 March 2020

1 reference

The Wilhelmine E. Key 2001 Invitational Lecture. Estimation of divergence times for a few mammalian and several primate species.

31 March 2020

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Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes

31 March 2020

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI1489

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Consolidated OpenCitations Corpus – April 2017

1710627

1710627

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference