PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells (Q44737517)

5 December 2017

PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells (English)

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5 December 2017

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5

Derek LeRoith

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5 December 2017

Hong Zhao

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5 December 2017

Joelle Dupont

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2

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5 December 2017

Shoshana Yakar

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3

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5 December 2017

Michael Karas

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4

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5 December 2017

language of work or name

English

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publication date

1 January 2004

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5 December 2017

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5 December 2017

23

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5 December 2017

786-794

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5 December 2017

3

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207162

5 December 2017

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cites work

Differential effects of phosphatidylinositol-3/Akt-kinase inhibition on apoptotic sensitization to cytokines in LNCaP and PCc-3 prostate cancer cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

Inhibition of vascular smooth muscle cell proliferation, migration, and survival by the tumor suppressor protein PTEN.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

Molecular kinetics of nerve growth factor receptor trafficking and activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

Superinduction of CYP1A1 gene expression. Regulation of 2,3,7,8- tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

The mRNA 5' cap-binding protein eIF4E and control of cell growth

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

Effects of proteasomal inhibitors on the maturation of the insulin proreceptor: an anatomical paradox

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

PI 3-kinases and PTEN: how opposites chemoattract

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

Insulin and IGF-1 induce different patterns of gene expression in mouse fibroblast NIH-3T3 cells: identification by cDNA microarray analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

Mechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

Molecular and cellular aspects of the insulin-like growth factor I receptor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

IGF-I receptor signaling in a prostatic cancer cell line with a PTEN mutation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

Retroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

PTEN: a new twist on β-catenin?

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207162

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207162

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5 December 2017

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