The somatic genomic landscape of glioblastoma (Q28300185)

56

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Giovanni Ciriello

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Houtan Noushmehr

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Debyani Chakravarty

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Cameron Brennan

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Erwin G. Van Meir

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Charles M. Perou

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Eric Lander

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Gad Getz

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Carrie Sougnez

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Peter W Laird

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Kenneth D Aldape

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Sofie R Salama

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J Zachary Sanborn

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Michael D Prados

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Jennifer Eschbacher

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Jennifer Eschbacher

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Gaetano Finocchiaro

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Mary Iacocca

36

Mary Iacocca

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Raju Kucherlapati

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Raju Kucherlapati

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D. Neil Hayes

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D Neil Hayes

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Paul Spellman

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Richard A Gibbs

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Richard Gibbs

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Daniel J Weisenberger

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Daniel J Weisenberger

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Gordon B. Mills

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Gordon B Mills

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Richard K. Wilson

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Richard Wilson

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John N Weinstein

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John Weinstein

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Lihua Zou

17

Lihua Zou

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author name string

Benito Campos

4

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Siyuan Zheng

7

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Samuel H Berman

10

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Brady Bernard

12

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Chang-Jiun Wu

13

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Giannicola Genovese

14

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Rahulsimham Vegesna

18

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Sachet A Shukla

19

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W K Yung

21

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Wei Zhang

22

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Andrew Sloan

29

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Keith L Black

30

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William Friedman

33

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David W Andrews

34

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Abhijit Guha

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Brian P O'Neill

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Greg Foltz

38

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Jerome Myers

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Robert Penny

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Marco Marra

Comprehensive molecular portraits of human breast tumours

46

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language of work or name

English

0 references

publication date

10 October 2013

0 references

published in

Cell

0 references

volume

155

0 references

page(s)

462-77

0 references

issue

2

0 references

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Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

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A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival

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TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

29 September 2017

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Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma

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Transforming fusions of FGFR and TACC genes in human glioblastoma

29 September 2017

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29 September 2017

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MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

29 September 2017

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STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

29 September 2017

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Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors

29 September 2017

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29 September 2017

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Emerging insights into the molecular and cellular basis of glioblastoma

29 September 2017

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Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network

29 September 2017

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Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

29 September 2017

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Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies

29 September 2017

1 reference

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Mutual exclusivity analysis identifies oncogenic network modules

29 September 2017

1 reference

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GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

29 September 2017

1 reference

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DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

Genetic pathways to primary and secondary glioblastoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

Double minute chromosomes in glioblastoma multiforme are revealed by precise reconstruction of oncogenic amplicons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

Comparative analysis of annexin-1 in neuroepithelial tumors shows altered expression with the grade of malignancy but is not associated with survival.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

Cyclooxygenase-2 expression in human gliomas: prognostic significance and molecular correlations

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500

A complete description of the EGF-receptor exon structure: implication in oncogenic activation and domain evolution.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910500