Hyperthermia enhances mapatumumab-induced apoptotic death through ubiquitin-mediated degradation of cellular FLIP(long) in human colon cancer cells (Q28397571)

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English	Hyperthermia enhances mapatumumab-induced apoptotic death through ubiquitin-mediated degradation of cellular FLIP(long) in human colon cancer cells	scientific article

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scholarly article

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Hyperthermia enhances mapatumumab-induced apoptotic death through ubiquitin-mediated degradation of cellular FLIP(long) in human colon cancer cells (English)

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apoptotic process

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1 reference

based on heuristic

inferred from title

author name string

X Song

1

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S-Y Kim

2

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Z Zhou

3

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E Lagasse

4

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Y T Kwon

5

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Y J Lee

6

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language of work or name

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publication date

4 April 2013

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Cell Death and Disease

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4

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4

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e577

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Regulation of CD95/Fas signaling at the DISC

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19 March 2017

Origin and function of ubiquitin-like proteins

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19 March 2017

FLIP and the death effector domain family

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

19 March 2017

A stochastic model for cancer stem cell origin in metastatic colon cancer

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19 March 2017

The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation

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19 March 2017

FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

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19 March 2017

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

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19 March 2017

Inhibition of death receptor signals by cellular FLIP

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19 March 2017

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

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19 March 2017

Protein degradation and protection against misfolded or damaged proteins

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7 April 2017

Hyperthermia-enhanced TRAIL- and mapatumumab-induced apoptotic death is mediated through mitochondria in human colon cancer cells

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29 September 2017

Celecoxib promotes c-FLIP degradation through Akt-independent inhibition of GSK3.

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29 September 2017

A Phase 1b/2 trial of mapatumumab in patients with relapsed/refractory non-Hodgkin's lymphoma

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29 September 2017

Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Effect of hyperthermia in combination with TRAIL on the JNK-Bim signal transduction pathway and growth of xenograft tumors

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29 September 2017

Cystatin B inhibition of TRAIL-induced apoptosis is associated with the protection of FLIP(L) from degradation by the E3 ligase itch in human melanoma cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Isolated hepatic perfusion with high-dose melphalan results in immediate alterations in tumor gene expression in patients with metastatic ocular melanoma

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Mapatumumab, a fully human agonistic monoclonal antibody that targets TRAIL-R1, in combination with gemcitabine and cisplatin: a phase I study.

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29 September 2017

PKC-mediated phosphorylation regulates c-FLIP ubiquitylation and stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Involvement of c-FLIP and survivin down-regulation in flexible heteroarotinoid-induced apoptosis and enhancement of TRAIL-initiated apoptosis in lung cancer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

ATM kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

c-FLIP: a key regulator of colorectal cancer cell death

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Effect of hyperthermia and chemotherapeutic agents on TRAIL-induced cell death in human colon cancer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Hyperthermia enhances tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human cancer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Fever-like hyperthermia controls T Lymphocyte persistence by inducing degradation of cellular FLIPshort.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Effect of hyperthermia on TRAIL-induced apoptotic death in human colon cancer cells: development of a novel strategy for regional therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Ubiquitin and ubiquitin-like proteins in cancer pathogenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Role of ubiquitylation in cellular membrane transport

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Rapid turnover of c-FLIPshort is determined by its unique C-terminal tail

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Isolated hepatic perfusion for the treatment of patients with colorectal cancer liver metastases after irinotecan-based therapy

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29 September 2017

Mechanisms of resistance to TRAIL-induced apoptosis in cancer

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29 September 2017

c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Treatment of liver metastases, an update on the possibilities and results

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

NF-kappaB signals induce the expression of c-FLIP.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

29 September 2017

Tumor necrosis factor (TNF) receptor-associated factor 7 is required for TNFα-induced Jun NH2-terminal kinase activation and promotes cell death by regulating polyubiquitination and lysosomal degradation of c-FLIP protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3641327

2 June 2018

A phase I study of hyperthermic isolated hepatic perfusion with oxaliplatin in the treatment of unresectable liver metastases from colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.104

21 January 2018

c-FLIP inhibits chemotherapy-induced colorectal cancer cell death

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https://api.crossref.org/works/10.1038%2FCDDIS.2013.104

21 January 2018

Overexpression of FABP3 promotes apoptosis through inducing mitochondrial impairment in embryonic cancer cells

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https://api.crossref.org/works/10.1038%2FCDDIS.2013.104

21 January 2018

ATM kinase activity modulates cFLIP protein levels: potential interplay between DNA damage signalling and TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.104

21 January 2018

Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells

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https://api.crossref.org/works/10.1038%2FCDDIS.2013.104

21 January 2018

Isolated hyperthermic liver perfusion with chemotherapy for liver malignancy

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https://pubmed.ncbi.nlm.nih.gov/23559011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of FLIPL is an independent marker of poor prognosis in colorectal cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23559011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1038/CDDIS.2013.104

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