Notch3 is dispensable for thymocyte β-selection and Notch1-induced T cell leukemogenesis (Q28477072)

2

0 references

Keli Xu

3

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Philaretos C Kousis

4

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Paul E Kowalski

5

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Greg Chang

6

0 references

Sean E Egan

7

0 references

Cynthia Guidos

Creative Commons Attribution 4.0 International

8

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language of work or name

English

0 references

publication date

2011

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published in

PLOS One

0 references

volume

6

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issue

9

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page(s)

e24937

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copyright license

start time

13 September 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

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Expression of Notch receptors, ligands, and target genes during development of the mouse mammary gland

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Notch dimerization is required for leukemogenesis and T-cell development

29 September 2017

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Lunatic fringe enhances competition for delta-like Notch ligands but does not overcome defective pre-TCR signaling during thymocyte beta-selection in vivo

29 September 2017

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Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.

29 September 2017

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NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network

29 September 2017

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Fine-scale staging of T cell lineage commitment in adult mouse thymus

29 September 2017

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Functions of notch signaling in the immune system: consensus and controversies

29 September 2017

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Targeting specific regions of the Notch3 ligand-binding domain induces apoptosis and inhibits tumor growth in lung cancer

29 September 2017

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Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis

29 September 2017

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Temporal Notch activation through Notch1a and Notch3 is required for maintaining zebrafish rhombomere boundaries

29 September 2017

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Identification of novel Notch target genes in T cell leukaemia

29 September 2017

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Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.

29 September 2017

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Linking Notch signaling to ischemic stroke

29 September 2017

1 reference

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Notch3 and the Notch3-upregulated RNA-binding protein HuD regulate Ikaros alternative splicing

29 September 2017

1 reference

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Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription

29 September 2017

1 reference

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Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation

29 September 2017

1 reference

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NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

29 September 2017

1 reference

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The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor.

29 September 2017

1 reference

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c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

29 September 2017

1 reference

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Notch3 gene amplification in ovarian cancer

29 September 2017

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Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate.

29 September 2017

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Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability

29 September 2017

1 reference

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Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism

29 September 2017

1 reference

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Notch3 is required for arterial identity and maturation of vascular smooth muscle cells

29 September 2017

1 reference

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Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation

29 September 2017

1 reference

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Activated Notch2 potentiates CD8 lineage maturation and promotes the selective development of B1 B cells.

29 September 2017

1 reference

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Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

29 September 2017

1 reference

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Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

29 September 2017

1 reference

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Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172312

Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172312

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172312

Intrathymic maturation of murine T lymphocytes from CD8+ precursors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172312

Delta-like 4 is indispensable in thymic environment specific for T cell development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172312

Notch-induced T cell development requires phosphoinositide-dependent kinase 1.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172312

Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172312

Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172312

Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172312

Developmental potential of CD4-8- thymocytes. Peripheral progeny include mature CD4-8- T cells bearing alpha beta T cell receptor.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3172312

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Regulation of T lymphopoiesis by Notch1 and Lunatic fringe-mediated competition for intrathymic niches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Notch signaling controls the generation and differentiation of early T lineage progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Requirement for Notch1 signals at sequential early stages of intrathymic T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Developmental and molecular characterization of emerging beta- and gammadelta-selected pre-T cells in the adult mouse thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Surface expression of Notch1 on thymocytes: correlation with the double-negative to double-positive transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Functional analysis of secreted and transmembrane proteins critical to mouse development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Notch3 is essential for regulation of the renal vascular tone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Functional diversity among Notch1, Notch2, and Notch3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024937

Modulation of Notch signaling by antibodies specific for the extracellular negative regulatory region of NOTCH3

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21931869

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21931869