Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice (Q28505715)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19523444%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19523444%20AND%20SRC:MED&resulttype=core&format=json

Insulin receptor substrate 2

31 January 2020

main subject

1 reference

GOA release 2020-03-11

author

Richard Killick

1

1 reference

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31 January 2020

Karelle Leroy

3

1 reference

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31 January 2020

Fiona Kerr

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19523444%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Jean-Pierre Brion

14

1 reference

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31 January 2020

Dominic J Withers

15

1 reference

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31 January 2020

Simon Lovestone

16

1 reference

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31 January 2020

author name string

Georgie Scales

2

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19523444%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Mirsada Causevic

4

2 references

24 January 2017

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31 January 2020

Claudie Hooper

5

2 references

24 January 2017

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31 January 2020

Laura Drinkwater

8

2 references

24 January 2017

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31 January 2020

Hind Al-Qassab

10

2 references

24 January 2017

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31 January 2020

John Stephenson

11

2 references

24 January 2017

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31 January 2020

Zehra Yilmaz

12

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19523444%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Elaine E Irvine

6

1 reference

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31 January 2020

Agharul I Choudhury

7

1 reference

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31 January 2020

K Peter Giese

13

1 reference

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31 January 2020

language of work or name

English

0 references

publication date

10 June 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19523444%20AND%20SRC:MED&resulttype=core&format=json

Biochemical and Biophysical Research Communications

31 January 2020

published in

2 references

24 January 2017

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31 January 2020

volume

386

2 references

24 January 2017

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31 January 2020

page(s)

257-262

1 reference

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31 January 2020

issue

1

2 references

24 January 2017

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Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

31 January 2020

cites work

1 reference

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Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation

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Disruption of IRS-2 causes type 2 diabetes in mice

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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29 September 2017

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Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity

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Brain IRS2 signaling coordinates life span and nutrient homeostasis

29 September 2017

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IGF-1-induced processing of the amyloid precursor protein family is mediated by different signaling pathways

29 September 2017

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Transthyretin inhibition of amyloid beta aggregation and toxicity

29 September 2017

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The role of insulin receptor substrate 2 in hypothalamic and beta cell function.

29 September 2017

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The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease

29 September 2017

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29 September 2017

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/19523444

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Insulin-like growth factor-1 and insulin mediate transient site-selective increases in tau phosphorylation in primary cortical neurons

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19523444

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BBRC.2009.06.032

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19523444%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19523444%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

2 references

24 January 2017