Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1 (Q28509366)

Delta like canonical Notch ligand 1

1 reference

Transmembrane protein 59

1 reference

A disintegrin and metallopeptidase domain 17

1 reference

RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

1 reference

Notch 1

1 reference

A disintegrin and metallopeptidase domain 7

1 reference

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

1 reference

Jagged 1

1 reference

author name string

Liang-Tung Yang

1

1 reference

24 January 2017

James T. Nichols

2

1 reference

24 January 2017

Christine Yao

3

1 reference

24 January 2017

Jennifer O. Manilay

4

1 reference

24 January 2017

Ellen A. Robey

5

1 reference

24 January 2017

Gerry Weinmaster

Molecular Biology of the Cell

6

1 reference

24 January 2017

1 February 2005

1 reference

24 January 2017

1 reference

24 January 2017

16

1 reference

24 January 2017

927–942

1 reference

24 January 2017

2

1 reference

24 January 2017

describes a project that uses

ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC545923/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments

1 reference

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Protein O -fucosyltransferase 1 is an essential component of Notch signaling pathways

19 March 2017

1 reference

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The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

19 March 2017

1 reference

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Furin cleavage is not a requirement for Drosophila Notch function

19 March 2017

1 reference

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Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe

19 March 2017

1 reference

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Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice

19 March 2017

1 reference

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Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain

19 March 2017

1 reference

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SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation

19 March 2017

1 reference

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Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation

19 March 2017

1 reference

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Notch signaling: from the outside in

19 March 2017

1 reference

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Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors

19 March 2017

1 reference

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Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2

19 March 2017

1 reference

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Fringe is a glycosyltransferase that modifies Notch

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

19 March 2017

1 reference

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

19 March 2017

1 reference

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Calcium depletion dissociates and activates heterodimeric notch receptors

19 March 2017

1 reference

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Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods

19 March 2017

1 reference

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Notch signaling: cell fate control and signal integration in development

19 March 2017

1 reference

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The Notch1 receptor is cleaved constitutively by a furin-like convertase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

19 March 2017

1 reference

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Nuclear access and action of notch in vivo

19 March 2017

1 reference

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Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis

19 March 2017

1 reference

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A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway

19 March 2017

1 reference

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Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jkappa or nuclear localization sequences retain the ability to associate with RBP-Jkappa and activate transcription

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Notch signaling in lymphocyte development and function

19 March 2017

1 reference

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Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

29 September 2017

1 reference

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Elasticity and adhesion force mapping reveals real-time clustering of growth factor receptors and associated changes in local cellular rheological properties

29 September 2017

1 reference

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Glycosylation regulates Notch signalling.

29 September 2017

1 reference

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Notch-induced proteolysis and nuclear localization of the Delta ligand

29 September 2017

1 reference

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The ADAMs family of metalloproteases: multidomain proteins with multiple functions

29 September 2017

1 reference

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Fringe modifies O-fucose on mouse Notch1 at epidermal growth factor-like repeats within the ligand-binding site and the Abruptex region

29 September 2017

1 reference

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Regulation of signal transduction pathways in development by glycosylation

29 September 2017

1 reference

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Modulation of receptor signaling by glycosylation: fringe is an O-fucose-beta1,3-N-acetylglucosaminyltransferase

29 September 2017

1 reference

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kuzbanian-mediated cleavage of Drosophila Notch

29 September 2017

1 reference

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Fringe modulation of Jagged1-induced Notch signaling requires the action of beta 4galactosyltransferase-1

29 September 2017

1 reference

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Hyperphosphorylation and association with RBP of the intracellular domain of Notch1.

29 September 2017

1 reference

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Ligand-induced signaling in the absence of furin processing of Notch1.

29 September 2017

1 reference

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Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Notch signal transduction: a real rip and more

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells

29 September 2017

1 reference

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Ligand endocytosis drives receptor dissociation and activation in the Notch pathway

29 September 2017

1 reference

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Dominant-negative mutation in the beta2 and beta6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Evidence for a physical interaction between presenilin and Notch

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Notch receptor activation inhibits oligodendrocyte differentiation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

lunatic fringe is an essential mediator of somite segmentation and patterning.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Defects in somite formation in lunatic fringe-deficient mice.

2 June 2018

1 reference

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The ins and outs of notch signaling

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

An O-fucose site in the ligand binding domain inhibits Notch activation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Modulation of notch-ligand binding by protein O-fucosyltransferase 1 and fringe.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Regulation of notch signaling by o-linked fucose.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

A secreted Delta1-Fc fusion protein functions both as an activator and inhibitor of Notch1 signaling

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

UDP-sugar transporter implicated in glycosylation and processing of Notch

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545923

Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15574878

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15574878