Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function (Q28510096)

24 January 2017

title

Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function (English)

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Phosphodiesterase 5A, cGMP-specific

24 January 2017

main subject

1 reference

GOA release 2020-03-11

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5

Joseph Califano

1 reference

24 January 2017

Paolo Serafini

1

1 reference

24 January 2017

Kristen Meckel

2

1 reference

24 January 2017

Michael Kelso

3

1 reference

24 January 2017

Kimberly Noonan

4

1 reference

24 January 2017

Wayne Koch

6

1 reference

24 January 2017

Luigi Dolcetti

7

1 reference

24 January 2017

Vincenzo Bronte

8

1 reference

24 January 2017

Ivan Borrello

9

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24 January 2017

language of work or name

English

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publication date

27 November 2006

1 reference

Journal of Experimental Medicine

24 January 2017

published in

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24 January 2017

volume

203

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24 January 2017

issue

12

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24 January 2017

page(s)

2691–2702

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The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance

24 January 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice

2 June 2018

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Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

21 January 2018

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Sildenafil and vardenafil, types 5 and 6 phosphodiesterase inhibitors, induce caspase-dependent apoptosis of B-chronic lymphocytic leukemia cells.

21 January 2018

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Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses

21 January 2018

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21 January 2018

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Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion

21 January 2018

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27 November 2018

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Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

27 November 2018

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Interleukin-2 expression by a subpopulation of primary T cells is linked to enhanced memory/effector function

21 January 2018

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12 December 2020

STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion

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12 December 2020

On the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients

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12 December 2020

Histological grade, perineural infiltration, tumour-infiltrating lymphocytes and apoptosis as determinants of long-term prognosis in prostatic adenocarcinoma

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12 December 2020

Tumor infiltrating lymphocytes in lymph node melanoma metastases: a histopathologic prognostic indicator and an expression of local immune response

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12 December 2020

Critical role of NK but not NKT cells in acute rejection of parental bone marrow cells in F1 hybrid mice

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12 December 2020

Myeloid differentiation treatment to diminish the presence of immune-suppressive CD34+ cells within human head and neck squamous cell carcinomas

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Identifiers

DOI

10.1084/JEM.20061104

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1 reference

1 reference

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