Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis (Q28512907)

25 January 2017

title

Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis (English)

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TGF-beta activated kinase 1/MAP3K7 binding protein 1

25 January 2017

main subject

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Mitogen-activated protein kinase kinase kinase 7

GOA release 2020-03-11

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GOA release 2020-03-11

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1 reference

4

Jun Ninomiya-Tsuji

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25 January 2017

Naoto Ueno

8

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author name string

Yoshihiro Komatsu

1

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25 January 2017

Hiroshi Shibuya

2

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25 January 2017

Naoki Takeda

3

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25 January 2017

Teruhito Yasui

5

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25 January 2017

Kenji Miyado

6

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25 January 2017

Tomohisa Sekimoto

7

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25 January 2017

Kunihiro Matsumoto

9

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25 January 2017

Gen Yamada

10

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25 January 2017

publication date

1 December 2002

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Mechanisms of Development

25 January 2017

published in

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25 January 2017

volume

119

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25 January 2017

issue

2

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25 January 2017

page(s)

239–249

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

25 January 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

Diversity in function and regulation of MAP kinase pathways

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7 January 2021

Mammalian MAP kinase signalling cascades

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7 January 2021

Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expression

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7 January 2021

Functions of c-Jun in liver and heart development

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7 January 2021

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

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7 January 2021

Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells

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7 January 2021

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

1 reference

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7 January 2021

BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6

1 reference

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7 January 2021

TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop

1 reference

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7 January 2021

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

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7 January 2021

SMADs: mediators and regulators of TGF-beta signaling

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7 January 2021

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

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7 January 2021

Defective angiogenesis in mice lacking endoglin

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7 January 2021

IKK1-deficient mice exhibit abnormal development of skin and skeleton

1 reference

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7 January 2021

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

1 reference

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7 January 2021

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

1 reference

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7 January 2021

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

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7 January 2021

Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos

1 reference

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7 January 2021

Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

1 reference

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7 January 2021

TGF-beta signaling by Smad proteins

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7 January 2021

Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation.

1 reference

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7 January 2021

Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4

1 reference

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7 January 2021

A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

1 reference

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7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

The MAP kinase cascade is essential for diverse signal transduction pathways

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7 January 2021

Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis

1 reference

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7 January 2021

TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

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7 January 2021

Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta).

1 reference

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7 January 2021

Phosphorylation-dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1

1 reference

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7 January 2021

ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-beta signaling

1 reference

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7 January 2021

Role of TAK1 and TAB1 in BMP signaling in early Xenopus development

1 reference

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7 January 2021

TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction

1 reference

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7 January 2021

TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase

1 reference

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7 January 2021

Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

Limb and skin abnormalities in mice lacking IKKalpha

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

Signaling inputs converge on nuclear effectors in TGF-beta signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

TGF-beta related genes in development

1 reference

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7 January 2021

Smads and early developmental signaling by the TGFbeta superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts

1 reference

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7 January 2021

A novel ES cell line, TT2, with high germline-differentiating potency

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

Resistance to fever induction and impaired acute-phase response in interleukin-1 beta-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2802%2900391-X

7 January 2021

10.1016/S0925-4773(02)00391-X

Identifiers

DOI

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