Plasma membrane profiling defines an expanded class of cell surface proteins selectively targeted for degradation by HCMV US2 in cooperation with UL141 (Q28546343)

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scientific article (publication date: April 2015)

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English	Plasma membrane profiling defines an expanded class of cell surface proteins selectively targeted for degradation by HCMV US2 in cooperation with UL141	scientific article (publication date: April 2015)

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5 March 2020

Plasma membrane profiling defines an expanded class of cell surface proteins selectively targeted for degradation by HCMV US2 in cooperation with UL141 (English)

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Michael P Weekes

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Richard J Stanton

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Gavin S Wilkie

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Andrew J Davison

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Gavin Wilkinson

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Gavin W G Wilkinson

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Jye-Lin Hsu

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Dick J H van den Boomen

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Peter Tomasec

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Robin Antrobus

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Eva Ruckova

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Daniel Sugrue

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14 April 2015

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e1004811

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14 April 2015

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A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

1 reference

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Structure of human cytomegalovirus UL141 binding to TRAIL-R2 reveals novel, non-canonical death receptor interactions

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Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141

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The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

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9 May 2017

HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cells

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Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses.

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Human cytomegalovirus US3 modulates destruction of MHC class I molecules

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Human cytomegalovirus UL40 signal peptide regulates cell surface expression of the NK cell ligands HLA-E and gpUL18

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/25875600

12 December 2020

based on heuristic

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1 reference

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12 December 2020

based on heuristic

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Human epidermal Langerhans cells express beta 1 integrins that mediate their adhesion to laminin and fibronectin

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12 December 2020

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Cytomegalovirus US2 destroys two components of the MHC class II pathway, preventing recognition by CD4+ T cells

1 reference

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based on heuristic

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10.1371/JOURNAL.PPAT.1004811

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5 March 2020

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