Lipoic acid restores age-associated impairment of brain energy metabolism through the modulation of Akt/JNK signaling and PGC1α transcriptional pathway (Q28568717)

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English	Lipoic acid restores age-associated impairment of brain energy metabolism through the modulation of Akt/JNK signaling and PGC1α transcriptional pathway	scientific journal article

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scholarly article

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23815272%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Lipoic acid restores age-associated impairment of brain energy metabolism through the modulation of Akt/JNK signaling and PGC1α transcriptional pathway (English)

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23815272%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

0 references

2

1 reference

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4 March 2020

author name string

Tianyi Jiang

1

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23815272%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Jia Yao

3

2 references

31 January 2017

Europe PubMed Central

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4 March 2020

Enrique Cadenas

5

2 references

31 January 2017

Europe PubMed Central

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4 March 2020

Roberta D Brinton

4

1 reference

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4 March 2020

publication date

29 July 2013

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4 March 2020

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23815272%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

12

2 references

31 January 2017

Europe PubMed Central

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4 March 2020

1021-1031

1 reference

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4 March 2020

6

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23815272%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential

1 reference

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19 March 2017

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

1 reference

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19 March 2017

Mitochondrial respiratory chain is involved in insulin-stimulated hydrogen peroxide production and plays an integral role in insulin receptor autophosphorylation in neurons

1 reference

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19 March 2017

Corticosterone impairs insulin-stimulated translocation of GLUT4 in the rat hippocampus

1 reference

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19 March 2017

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

1 reference

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19 March 2017

Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

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19 March 2017

AMPK: a nutrient and energy sensor that maintains energy homeostasis

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7 April 2017

Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice

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7 April 2017

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

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7 April 2017

Transcriptional paradigms in mammalian mitochondrial biogenesis and function

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7 April 2017

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha

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7 April 2017

Metabolic triad in brain aging: mitochondria, insulin/IGF-1 signalling and JNK signalling

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29 September 2017

Mitochondrial energy metabolism and redox signaling in brain aging and neurodegeneration

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29 September 2017

Defective leptin-AMP-dependent kinase pathway induces nitric oxide release and contributes to mitochondrial dysfunction and obesity in ob/ob mice

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29 September 2017

JNK: a stress-activated protein kinase therapeutic strategies and involvement in Alzheimer's and various neurodegenerative abnormalities

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29 September 2017

Insulin signaling meets mitochondria in metabolism

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29 September 2017

Retracted: Increased muscle PGC-1α expression protects from sarcopenia and metabolic disease during aging

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29 September 2017

Reactive oxygen species enhance insulin sensitivity

1 reference

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29 September 2017

Regulation of neuron mitochondrial biogenesis and relevance to brain health

1 reference

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29 September 2017

Insulin-stimulated translocation of GLUT4 to the plasma membrane in rat hippocampus is PI3-kinase dependent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3819405

29 September 2017

Elevated neuronal nitric oxide synthase expression during ageing and mitochondrial energy production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3819405

29 September 2017

Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging

1 reference

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29 September 2017

Insulin and JNK: optimizing metabolic homeostasis and lifespan

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3819405

29 September 2017

Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats

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29 September 2017

The mitochondrial energy transduction system and the aging process

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3819405

29 September 2017

Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

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29 September 2017

The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration

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29 September 2017

(R)-alpha-lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis

1 reference

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29 September 2017

Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation

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29 September 2017

Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis

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29 September 2017

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27 November 2018

Role for mitochondrial oxidants as regulators of cellular metabolism

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29 September 2017

Influence of alpha-lipoic acid on intracellular glutathione in vitro and in vivo

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29 September 2017

Alpha-lipoic acid decreases thiol reactivity of the insulin receptor and protein tyrosine phosphatase 1B in 3T3-L1 adipocytes

1 reference

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3 June 2018

Chronic insulin hypoglycemia induces GLUT-3 protein in rat brain neurons.

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3 June 2018

The insulin-dependent biosynthesis of GLUT1 and GLUT3 glucose transporters in L6 muscle cells is mediated by distinct pathways. Roles of p21ras and pp70 S6 kinase

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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21 January 2018

Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease.

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21 January 2018

Alpha-lipoic acid protects rat cortical neurons against cell death induced by amyloid and hydrogen peroxide through the Akt signalling pathway

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21 January 2018

c-Jun N-terminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons

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27 November 2018

Identification by mutation of the tyrosine residues in the insulin receptor substrate-1 affecting association with the tyrosine phosphatase 2C and phosphatidylinositol 3-kinase

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27 November 2018

Roles of superoxide radical anion in signal transduction mediated by reversible regulation of protein-tyrosine phosphatase 1B

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12 December 2020

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Detection of the GLUT3 facilitative glucose transporter in rat L6 muscle cells: regulation by cellular differentiation, insulin and insulin-like growth factor-I

1 reference

https://pubmed.ncbi.nlm.nih.gov/23815272

12 December 2020

based on heuristic

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PGC-1α protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model

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https://pubmed.ncbi.nlm.nih.gov/23815272

12 December 2020

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Age-related changes in LTP and antioxidant defenses are reversed by an α-lipoic acid-enriched diet

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12 December 2020

based on heuristic

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Identifiers

10.1111/ACEL.12127

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

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4 March 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23815272%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23815272%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

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