TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver (Q28589957)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

Transcription factor 7 like 2, T cell specific, HMG box

9 March 2020

main subject

glucose

0 references

1 reference

GOA release 2020-03-11

author

Seung-Hoi Koo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

author name string

Kyoung-Jin Oh

1

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Jinyoung Park

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Su Sung Kim

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Hyunhee Oh

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Cheol Soo Choi

5

2 references

31 January 2017

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9 March 2020

publication date

27 September 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

8

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

issue

9

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

page(s)

e1002986

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

9 March 2020

copyright license

start time

27 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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17 March 2017

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17 March 2017

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Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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TCF7L2 variation predicts hyperglycemia incidence in a French general population: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study

29 September 2017

1 reference

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TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

29 September 2017

1 reference

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Identification of a cAMP response element within the glucose- 6-phosphatase hydrolytic subunit gene promoter which is involved in the transcriptional regulation by cAMP and glucocorticoids in H4IIE hepatoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

Cyclic AMP-dependent protein kinase regulates transcription of the phosphoenolpyruvate carboxykinase gene but not binding of nuclear factors to the cyclic AMP regulatory element

29 September 2017

1 reference

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Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

CRTC2 (TORC2) contributes to the transcriptional response to fasting in the liver but is not required for the maintenance of glucose homeostasis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

Effects of TCF7L2 polymorphisms on obesity in European populations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. II. Identification of cAMP and glucocorticoid regulatory domains

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human -Cells and Adipose Tissue and Strong Association With Type 2 Diabetes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3459990

Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23028378

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/23028378

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1002986

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23028378%20AND%20SRC:MED&resulttype=core&format=json