Physiological levels of Pik3ca(H1047R) mutation in the mouse mammary gland results in ductal hyperplasia and formation of ERα-positive tumors (Q28729079)

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scientific article (publication date: 2012)

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English	Physiological levels of Pik3ca(H1047R) mutation in the mouse mammary gland results in ductal hyperplasia and formation of ERα-positive tumors	scientific article (publication date: 2012)

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3 February 2020

Physiological levels of Pik3ca(H1047R) mutation in the mouse mammary gland results in ductal hyperplasia and formation of ERα-positive tumors (English)

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3 February 2020

Patrick O. Humbert

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Wayne A. Phillips

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Anjali Tikoo

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Vincent Roh

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Karen G Montgomery

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Ivan Ivetac

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Paul Waring

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Rebecca Pelzer

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3 February 2020

Lauren Hare

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Mark Shackleton

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30 May 2012

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3 February 2020

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3 February 2020

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3 February 2020

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3 February 2020

e36924

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3 February 2020

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Creative Commons Attribution 4.0 International

30 May 2012

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Oncogenic mutations of PIK3CA in human cancers

1 reference

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17 March 2017

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17 March 2017

Generation of a functional mammary gland from a single stem cell

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3 June 2018

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Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heterogeneous tumors

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3 June 2018

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3 June 2018

PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer

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3 June 2018

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3 June 2018

PIK3CA mutations mostly begin to develop in ductal carcinoma of the breast

1 reference

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3 June 2018

PIK3CA mutation associates with improved outcome in breast cancer.

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Activation of phosphatidylinositol 3-kinase by membrane localization of p110alpha predisposes mammary glands to neoplastic transformation

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1 reference

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1 reference

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1 reference

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1 reference

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27 November 2018

Mutation of the PIK3CA gene in ovarian and breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22666336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenic mutations of PIK3CA in human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/22666336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIK3CA exon 20 mutation is independently associated with a poor prognosis in breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22666336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0036924

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3 February 2020

2012PLoSO...736924T

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1 reference

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3 February 2020

1 reference

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3 February 2020

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