IL-15 regulates homeostasis and terminal maturation of NKT cells (Q28741430)

Andrew I Flyak

3

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Jelena S Bezbradica

Jelena S Bezbradica

2

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Aleksandar K Stanic

Aleksandar K Stanic

7

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Sebastian Joyce

Sebastian Joyce

12

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Mark R. Boothby

8

Mark R Boothby

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author name string

Laura E Gordy

1

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Charles T Spencer

4

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Alexis Dunkle

5

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Jingchun Sun

6

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You-Wen He

9

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Zhongming Zhao

describes a project that uses

10

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language of work or name

English

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publication date

15 December 2011

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published in

Journal of Immunology

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volume

187

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issue

12

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page(s)

6335-45

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limma

1 reference

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/3237743

inferred from PubMed Central ID database lookup

cites work

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The Src family tyrosine kinase Fyn regulates natural killer T cell development

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The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells

3 June 2018

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Distinct roles for signals relayed through the common cytokine receptor gamma chain and interleukin 7 receptor alpha chain in natural T cell development

3 June 2018

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Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

3 June 2018

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A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection

3 June 2018

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IL-15Rα of radiation-resistant cells is necessary and sufficient for thymic invariant NKT cell survival and functional maturation.

3 June 2018

1 reference

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Selective requirement for c-Myc at an early stage of V(alpha)14i NKT cell development

27 November 2018

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The adaptor molecule signaling lymphocytic activation molecule-associated protein (SAP) regulates IFN-gamma and IL-4 production in V alpha 14 transgenic NKT cells via effects on GATA-3 and T-bet expression

27 November 2018

1 reference

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Rel/NF-kappaB family member RelA regulates NK1.1- to NK1.1+ transition as well as IL-15-induced expansion of NKT cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237743

Enforced expression of Bcl-2 partially restores cell numbers but not functions of TCRgammadelta intestinal intraepithelial T lymphocytes in IL-15-deficient mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237743

Long-term retention of mature NK1.1+ NKT cells in the thymus.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237743

Genetic evidence supporting selection of the Valpha14i NKT cell lineage from double-positive thymocyte precursors

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237743

T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237743

Cutting edge: the ontogeny and function of Va14Ja18 natural T lymphocytes require signal processing by protein kinase C theta and NF-kappa B.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237743

NF-kappa B controls cell fate specification, survival, and molecular differentiation of immunoregulatory natural T lymphocytes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237743

Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237743

NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237743

Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237743

Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237743

Enforced expression of Bcl-2 restores the number of NK cells, but does not rescue the impaired development of NKT cells or intraepithelial lymphocytes, in IL-2/IL-15 receptor beta-chain-deficient mice

27 November 2018

1 reference

12 December 2020

Regulation of NKT cell development by SAP, the protein defective in XLP

1 reference

12 December 2020

Peripheral NK1.1- NKT Cells Are Mature and Functionally Distinct from Their Thymic Counterparts

1 reference

12 December 2020

Cutting edge: LFA-1 is required for liver NK1.1+TCR alpha beta+ cell development: evidence that liver NK1.1+TCR alpha beta+ cells originate from multiple pathways

1 reference

12 December 2020

Role for IL-15/IL-15 receptor beta-chain in natural killer 1.1+ T cell receptor-alpha beta+ cell development

1 reference

12 December 2020

Regulation of Th2 cytokine expression in NKT cells: unconventional use of Stat6, GATA-3, and NFAT2

1 reference

12 December 2020

A thymic precursor to the NK T cell lineage

1 reference

12 December 2020

Characterization and functional analysis of mouse invariant natural T (iNKT) cells

1 reference

12 December 2020

Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

1 reference

12 December 2020

Homeostasis of V alpha 14i NKT cells

1 reference

12 December 2020

Granulocyte-Macrophage Colony-Stimulating Factor Regulates Effector Differentiation of Invariant Natural Killer T Cells during Thymic Ontogeny

1 reference

12 December 2020

IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

1 reference

12 December 2020

Cutting Edge: Signaling Lymphocytic Activation Molecule-Associated Protein Controls NKT Cell Functions

1 reference

12 December 2020

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1003965

1 reference

1 reference

1 reference

PubMed publication ID

22084435

1 reference