The ribonuclease activity of SAMHD1 is required for HIV-1 restriction (Q29147390)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction (English)

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

9 March 2020

main subject

HIV

0 references

1 reference

GOA release 2020-03-11

ribonuclease activity

1 reference

GOA release 2020-03-11

author

Jongsu Choi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Alberto Brandariz-Nuñez

10

1 reference

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9 March 2020

11

Felipe Diaz-Griffero

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

9

Tommy E White

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

author name string

Jeongmin Ryoo

1

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Changhoon Oh

3

2 references

4 April 2017

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9 March 2020

Sungchul Kim

4

2 references

4 April 2017

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9 March 2020

Minji Seo

5

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Seok-Young Kim

6

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Daekwan Seo

7

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Jongkyu Kim

8

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Cheol-Heui Yun

12

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Baek Kim

14

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Daehyun Baek

15

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Kwangseog Ahn

16

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Joseph A Hollenbaugh

13

1 reference

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9 March 2020

language of work or name

English

0 references

publication date

20 July 2014

1 reference

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9 March 2020

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

20

2 references

4 April 2017

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9 March 2020

page(s)

936-941

1 reference

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9 March 2020

issue

8

2 references

4 April 2017

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Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase

9 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Mechanism of allosteric activation of SAMHD1 by dGTP

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Fast gapped-read alignment with Bowtie 2

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Restriction of virus infection but not catalytic dNTPase activity is regulated by phosphorylation of SAMHD1.

9 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Single-stranded nucleic acids promote SAMHD1 complex formation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Reversible cross-linking combined with immunoprecipitation to study RNA-protein interactions in vivo

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Site-directed mutagenesis of the conserved Asp-443 and Asp-498 carboxy-terminal residues of HIV-1 reverse transcriptase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318684

Separation of copurifying GroEL from glutathione-S-transferase fusion proteins

3 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25038827

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

New Insights into the Mechanism of RNA Degradation by Ribonuclease II

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25038827

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NM.3626

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 March 2020

1021735220

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25038827%20AND%20SRC:MED&resulttype=core&format=json