Dichotomous actions of NF-kappaB signaling pathways in heart (Q30390478)

21 June 2017

Dichotomous actions of NF-kappaB signaling pathways in heart (English)

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21 June 2017

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Rimpy Dhingra

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21 June 2017

James A Shaw

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2

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21 June 2017

Yaron Aviv

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3

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21 June 2017

Lorrie A Kirshenbaum

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4

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21 June 2017

language of work or name

English

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publication date

25 May 2010

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Journal of Cardiovascular Translational Research

21 June 2017

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21 June 2017

3

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4

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21 June 2017

344-354

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https://scigraph.springernature.com/pub.10.1007/s12265-010-9195-5

21 June 2017

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cites work

Disruption of NF-kappaB signaling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression

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TNF-alpha antibodies are as effective as ischemic preconditioning in reducing infarct size in rabbits

21 January 2018

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I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding

21 January 2018

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Activation of interleukin-6 gene expression through the NF-kappa B transcription factor

21 January 2018

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Hypoxia-induced endothelial apoptosis through nuclear factor-kappaB (NF-kappaB)-mediated bcl-2 suppression: in vivo evidence of the importance of NF-kappaB in endothelial cell regulation

21 January 2018

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Tumor necrosis factor-alpha confers resistance to hypoxic injury in the adult mammalian cardiac myocyte.

21 January 2018

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Proteasome inhibition ablates activation of NF-kappa B in myocardial reperfusion and reduces reperfusion injury

21 January 2018

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Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required

21 January 2018

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NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

21 January 2018

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A mechanistic role for cardiac myocyte apoptosis in heart failure

21 January 2018

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Induction of cyclooxygenase-2 and activation of nuclear factor-kappaB in myocardium of patients with congestive heart failure

21 January 2018

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Cardioprotection involves activation of NF-kappa B via PKC-dependent tyrosine and serine phosphorylation of I kappa B-alpha

21 January 2018

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Transcriptional regulation via the NF-kappaB signaling module.

21 January 2018

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12 December 2020

Overexpression of cardiac I-kappaBalpha prevents endotoxin-induced myocardial dysfunction

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12 December 2020

Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD)

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12 December 2020

Tumor necrosis factor-alpha and interleukin-1beta synergistically depress human myocardial function

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12 December 2020

Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB.

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12 December 2020

Nuclear factor-kappaB protects the adult cardiac myocyte against ischemia-induced apoptosis in a murine model of acute myocardial infarction.

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12 December 2020

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

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12 December 2020

Pyrrolidine dithiocarbamate attenuate shock wave induced MDCK cells injury via inhibiting nuclear factor-kappa B activation

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12 December 2020

Nuclear factor-kappaB-mediated cell survival involves transcriptional silencing of the mitochondrial death gene BNIP3 in ventricular myocytes

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12 December 2020

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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12 December 2020

Tumor necrosis factor induces apoptosis (programmed cell death) in normal endothelial cells in vitro

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12 December 2020

Circuitry of nuclear factor kappaB signaling

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12 December 2020

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

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12 December 2020

A direct requirement of nuclear factor-kappa B for suppression of apoptosis in ventricular myocytes

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12 December 2020

The I kappa B proteins: members of a multifunctional family

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12 December 2020

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

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12 December 2020

Tumor necrosis factor-alpha and tumor necrosis factor receptors in the failing human heart

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12 December 2020

Promoter of the human NF-kappa B p50/p105 gene. Regulation by NF-kappa B subunits and by c-REL.

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12 December 2020

Lipopolysaccharide pretreatment attenuates myocardial infarct size: A possible mechanism involving heat shock protein 70-inhibitory kappaBalpha complex and attenuation of nuclear factor kappaB.

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12 December 2020

Induction of nuclear factor kappaB and activation protein 1 in postischemic myocardium

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12 December 2020

Contenders in FasL/TNF death signaling

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12 December 2020

The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression

1 reference

12 December 2020

Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction

1 reference

12 December 2020

A proteasome inhibitor confers cardioprotection

1 reference

12 December 2020

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

1 reference

12 December 2020

Human RelB (I-Rel) functions as a kappa B site-dependent transactivating member of the family of Rel-related proteins

1 reference

12 December 2020

Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer

1 reference

12 December 2020

The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation

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12 December 2020

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

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12 December 2020

NF-kappaB signals induce the expression of c-FLIP.

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12 December 2020

Dynamic shuttling of nuclear factor kappa B between the nucleus and cytoplasm as a consequence of inhibitor dissociation

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12 December 2020

NF-kappa B, KBF1, dorsal, and related matters

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12 December 2020

Nuclear factor-kappaB represses hypoxia-induced mitochondrial defects and cell death of ventricular myocytes.

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12 December 2020

Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity

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12 December 2020

Commitment, fusion and biochemical differentiation of a myogenic cell line in the absence of DNA synthesis.

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12 December 2020

Bcl-2 activates the transcription factor NFkappaB through the degradation of the cytoplasmic inhibitor IkappaBalpha

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12 December 2020

Limb and skin abnormalities in mice lacking IKKalpha

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12 December 2020

p53 and E2F-1 cooperate to mediate apoptosis

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12 December 2020

Induction of endothelial cell apoptosis by TNF alpha: modulation by inhibitors of protein synthesis

1 reference

12 December 2020

NF-kappa B: ten years after

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12 December 2020

Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes

1 reference

12 December 2020

Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivative

1 reference

12 December 2020

A family of ligands for the TNF receptor superfamily

1 reference

12 December 2020

The alternative NF-kappaB pathway from biochemistry to biology: pitfalls and promises for future drug development

1 reference

12 December 2020

Linkage of the BH4 domain of Bcl-2 and the nuclear factor kappaB signaling pathway for suppression of apoptosis

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12 December 2020

NF-kappaB as a critical link between inflammation and cancer

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12 December 2020

Human myocardial tissue TNFalpha expression following acute global ischemia in vivo

1 reference

12 December 2020

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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12 December 2020

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

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12 December 2020

Cancer and inflammation: promise for biologic therapy.

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12 December 2020

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

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12 December 2020

Divergent tumor necrosis factor receptor-related remodeling responses in heart failure: role of nuclear factor-kappaB and inflammatory activation

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12 December 2020

Overexpression of Ref-1 inhibits hypoxia and tumor necrosis factor-induced endothelial cell apoptosis through nuclear factor-kappab-independent and -dependent pathways

1 reference

12 December 2020

Inhibition of cardiac myocyte apoptosis improves cardiac function and abolishes mortality in the peripartum cardiomyopathy of Galpha(q) transgenic mice

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12 December 2020

Activation of NF-kappa B and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells

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12 December 2020

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

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12 December 2020

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

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12 December 2020

Adenoviral gene transfer of activated phosphatidylinositol 3'-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro

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12 December 2020

Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization

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12 December 2020

Antagonism of E2F-1 regulated Bnip3 transcription by NF-kappaB is essential for basal cell survival

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12 December 2020

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

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12 December 2020

NF-kappaB at the crossroads of life and death

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12 December 2020

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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12 December 2020

Apoptosis in the failing human heart

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12 December 2020

Improved myocardial ischemia/reperfusion injury in mice lacking tumor necrosis factor-alpha

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12 December 2020

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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12 December 2020

Ischemia-reperfusion of rat myocardium activates nuclear factor-KappaB and induces neutrophil infiltration via lipopolysaccharide-induced CXC chemokine

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12 December 2020

Development and proliferative capacity of cardiac muscle cells

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12 December 2020

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

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12 December 2020

Phosphorylation of the PEST domain of IkappaBbeta regulates the function of NF-kappaB/IkappaBbeta complexes

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12 December 2020

Cardiac-specific abrogation of NF- kappa B activation in mice by transdominant expression of a mutant I kappa B alpha

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12 December 2020

Cardiac release of cytokines and inflammatory responses in acute myocardial infarction

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12 December 2020

IKKalpha controls formation of the epidermis independently of NF-kappaB.

1 reference

12 December 2020

NF-kappa B p100 is one of the high-molecular-weight proteins complexed with the v-Rel oncoprotein in transformed chicken spleen cells.

1 reference

12 December 2020

TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90

1 reference

12 December 2020

Cardiac reanimation: targeting cardiomyocyte death by BNIP3 and NIX/BNIP3L.

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12 December 2020

IKKbeta inhibition attenuates myocardial injury and dysfunction following acute ischemia-reperfusion injury

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12 December 2020

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

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12 December 2020

Regulation of hypoxia-inducible factor-1alpha by NF-kappaB

1 reference

12 December 2020

The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression

1 reference

12 December 2020

The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity.

1 reference

12 December 2020

p105, the NF-kappa B p50 precursor protein, is one of the cellular proteins complexed with the v-Rel oncoprotein in transformed chicken spleen cells

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12 December 2020

Signaling to NF-kappaB

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12 December 2020

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

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12 December 2020

Cytokine mRNA expression in postischemic/reperfused myocardium.

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12 December 2020

Apoptosis in myocytes in end-stage heart failure

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12 December 2020

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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12 December 2020

10.1007/S12265-010-9195-5

Identifiers

DOI

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Dimensions Publication ID

21 June 2017

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