Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma. (Q30408885)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24140934%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma (English)

1 reference

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28 February 2020

3

1 reference

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28 February 2020

Luis Del Valle

8

1 reference

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28 February 2020

author name string

Zhiqiang Qin

1

1 reference

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28 February 2020

Lu Dai

2

1 reference

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28 February 2020

Can Senkal

4

1 reference

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28 February 2020

Wenxue Wang

5

1 reference

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28 February 2020

Tom Reske

6

1 reference

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28 February 2020

Karlie Bonstaff

7

1 reference

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28 February 2020

Paulo Rodriguez

9

1 reference

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28 February 2020

Christina Voelkel-Johnson

11

1 reference

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28 February 2020

Charles D Smith

12

1 reference

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28 February 2020

Besim Ogretmen

13

1 reference

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28 February 2020

Chris Parsons

14

1 reference

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28 February 2020

Erik Flemington

10

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28 February 2020

publication date

18 October 2013

1 reference

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Molecular Cancer Therapeutics

28 February 2020

published in

1 reference

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28 February 2020

volume

13

1 reference

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28 February 2020

issue

1

1 reference

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28 February 2020

page(s)

154-164

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Autophagy: shaping the tumor microenvironment and therapeutic response.

28 February 2020

cites work

1 reference

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Leucine zipper domain is required for Kaposi sarcoma-associated herpesvirus (KSHV) K-bZIP protein to interact with histone deacetylase and is important for KSHV replication

20 June 2018

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20 June 2018

HIV-associated lymphoma

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Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis

20 June 2018

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Extracellular Hsp90 serves as a co-factor for NF-κB activation and cellular pathogenesis induced by an oncogenic herpesvirus.

20 June 2018

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Cooperative roles for emmprin and LYVE-1 in the regulation of chemoresistance for primary effusion lymphoma

20 June 2018

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Targeting NFĸB mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2

20 June 2018

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Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts

20 June 2018

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A human herpesvirus miRNA attenuates interferon signaling and contributes to maintenance of viral latency by targeting IKKε.

20 June 2018

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Extracellular and intracellular actions of sphingosine-1-phosphate

20 June 2018

1 reference

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Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase

20 June 2018

1 reference

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Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma

20 June 2018

1 reference

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Extracellular Hsp90 serves as a co-factor for MAPK activation and latent viral gene expression during de novo infection by KSHV.

20 June 2018

1 reference

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A human herpesvirus microRNA inhibits p21 expression and attenuates p21-mediated cell cycle arrest

20 June 2018

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A novel sphingosine kinase inhibitor induces autophagy in tumor cells

20 June 2018

1 reference

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Upregulation of xCT by KSHV-encoded microRNAs facilitates KSHV dissemination and persistence in an environment of oxidative stress

20 June 2018

1 reference

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Regulation of NF-kappaB inhibitor IkappaBalpha and viral replication by a KSHV microRNA

20 June 2018

1 reference

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Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2

20 June 2018

1 reference

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Regulation of KSHV lytic switch protein expression by a virus-encoded microRNA: an evolutionary adaptation that fine-tunes lytic reactivation

20 June 2018

1 reference

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Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic Acid

20 June 2018

1 reference

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Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate.

20 June 2018

1 reference

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Human cytomegalovirus regulates bioactive sphingolipids

20 June 2018

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Induction of paclitaxel resistance by the Kaposi's sarcoma-associated herpesvirus latent protein LANA2.

20 June 2018

1 reference

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PS-341 or a combination of arsenic trioxide and interferon-alpha inhibit growth and induce caspase-dependent apoptosis in KSHV/HHV-8-infected primary effusion lymphoma cells

20 June 2018

1 reference

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Primary effusion lymphoma

20 June 2018

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Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus lymphomas: implications for therapy.

20 June 2018

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Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling

20 June 2018

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Activation of NF-kappaB by the latent vFLIP gene of Kaposi's sarcoma-associated herpesvirus is required for the spindle shape of virus-infected endothelial cells and contributes to their proinflammatory phenotype

20 June 2018

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Effusion and solid lymphomas have distinctive gene and protein expression profiles in an animal model of primary effusion lymphoma

20 June 2018

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20 June 2018

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Biologically active sphingolipids in cancer pathogenesis and treatment

20 June 2018

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Failure to eradicate AIDS-associated primary effusion lymphoma with high-dose chemotherapy and autologous stem cell reinfusion: case report and literature review

20 June 2018

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Sphingosine kinase mediates activation of extracellular signal-related kinase and Akt by respiratory syncytial virus.

20 June 2018

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Chromatin remodeling of the Kaposi's sarcoma-associated herpesvirus ORF50 promoter correlates with reactivation from latency

20 June 2018

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Discovery and evaluation of inhibitors of human sphingosine kinase

20 June 2018

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VEGF receptor expression and signaling in human bladder tumors

20 June 2018

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Sphingosine kinase, sphingosine-1-phosphate, and apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918494

Kaposi's sarcoma-associated herpesvirus induces the phosphatidylinositol 3-kinase-PKC-zeta-MEK-ERK signaling pathway in target cells early during infection: implications for infectivity

20 June 2018

1 reference

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Long-term remission of an AIDS-related primary effusion lymphoma with antiviral therapy

20 June 2018

1 reference

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CREB-binding protein and histone deacetylase regulate the transcriptional activity of Kaposi's sarcoma-associated herpesvirus open reading frame 50

20 June 2018

1 reference

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A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus

20 June 2018

1 reference

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Antiviral drug susceptibility of human herpesvirus 8

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918494

Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy

20 June 2018

1 reference

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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918494

Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas

20 June 2018

1 reference

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Human herpesvirus-8 (HHV-8)-associated primary effusion lymphoma in two renal transplant recipients receiving rapamycin

20 June 2018

1 reference

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Prognostic Factors and Outcome of Human Herpesvirus 8–Associated Primary Effusion Lymphoma in Patients With AIDS

26 November 2018

1 reference

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Antitumor effects of bortezomib (PS-341) on primary effusion lymphomas

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918494

Clinical features and outcome of primary effusion lymphoma in HIV-infected patients: a single-institution study.

26 November 2018

1 reference

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Induction of pro-angiogenic signaling by a synthetic peptide derived from the second intracellular loop of S1P3 (EDG3).

26 November 2018

1 reference

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Inhibition of NF-kappaB induces apoptosis of KSHV-infected primary effusion lymphoma cells.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3918494

Valproic acid induces human herpesvirus 8 lytic gene expression in BCBL-1 cells

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24140934

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24140934

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Primary effusion lymphoma: successful treatment with highly active antiretroviral therapy and rituximab

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24140934

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1535-7163.MCT-13-0466

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24140934%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24140934%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24140934%20AND%20SRC:MED&resulttype=core&format=json