heat shock protein family D (Hsp60) member 1 (Q3047550)

GroEL-like apical domain superfamily

1 reference

GroEL-like equatorial domain superfamily

1 reference

TCP-1-like chaperonin intermediate domain superfamily

1 reference

Chaperonin Cpn60, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

single-stranded DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

13 references

8 April 2019

A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

GTP binding controls complex formation by the human ROCO protein MASL1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Next-generation sequencing to generate interactome datasets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Toward an understanding of the protein interaction network of the human liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Identification of Heat Shock Protein 60 as a Regulator of Neutral Sphingomyelinase 2 and Its Role in Dopamine Uptake

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Proteomic profiling of cellular proteins interacting with the hepatitis C virus core protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

double-stranded RNA binding

1 reference

8 April 2019

Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

DNA replication origin binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

2 references

protein folding chaperone activity

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

unfolded protein binding

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

The importance of a mobile loop in regulating chaperonin/ co-chaperonin interaction: humans versus Escherichia coli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

26 September 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

high-density lipoprotein particle binding

1 reference

8 April 2019

Heat shock protein 60 is a high-affinity high-density lipoprotein binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

LAP, an alcohol acetaldehyde dehydrogenase enzyme in Listeria, promotes bacterial adhesion to enterocyte-like Caco-2 cells only in pathogenic species

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

Heat shock protein 60 is a high-affinity high-density lipoprotein binding protein

apolipoprotein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

apolipoprotein A-I binding

1 reference

8 April 2019

Heat shock protein 60 is a high-affinity high-density lipoprotein binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

lipopolysaccharide binding

1 reference

8 April 2019

Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

cyclin-dependent protein kinase activating kinase holoenzyme complex

cell component

1 reference

26 September 2017

A yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIH

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

lipopolysaccharide receptor complex

1 reference

8 April 2019

Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

Heat shock proteins 70 and 60 share common receptors which are expressed on human monocyte-derived but not epidermal dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

6 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

26 September 2017

Human 2'-phosphodiesterase localizes to the mitochondrial matrix with a putative function in mitochondrial RNA turnover

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

26 September 2017

Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

26 September 2017

Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

1 reference

8 April 2019

Heat shock proteins 70 and 60 share common receptors which are expressed on human monocyte-derived but not epidermal dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

Heat shock proteins 70 and 60 share common receptors which are expressed on human monocyte-derived but not epidermal dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

Large-scale proteomics and phosphoproteomics of urinary exosomes

extracellular exosome

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

26 September 2017

Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

1 reference

26 September 2017

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Cyclin B1/Cdk1 coordinates mitochondrial respiration for cell-cycle G2/M progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Knockdown of human COX17 affects assembly and supramolecular organization of cytochrome c oxidase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

Plasma heat shock protein 60 and cardiovascular disease risk: the role of psychosocial, genetic, and biological factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

mitochondrial inner membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

26 September 2017

Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

26 September 2017

Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

1 reference

8 April 2019

Heat shock protein 60 is a high-affinity high-density lipoprotein binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

3 references

8 April 2019

Cell surface localization of the 60 kDa heat shock chaperonin protein (hsp60) in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

gammadelta T cells lyse autologous and allogenic oesophageal tumours: involvement of heat-shock proteins in the tumour cell lysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Heat shock proteins 70 and 60 share common receptors which are expressed on human monocyte-derived but not epidermal dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

26 September 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Human 2'-phosphodiesterase localizes to the mitochondrial matrix with a putative function in mitochondrial RNA turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

protein-containing complex

HDA

Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells

extracellular exosome

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

chaperone-mediated protein complex assembly

HDA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

positive regulation of interleukin-12 production

ISS

1 reference

8 April 2019

Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

positive regulation of interleukin-10 production

1 reference

8 April 2019

Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

positive regulation of macrophage activation

ISS

1 reference

8 April 2019

Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

MyD88-dependent toll-like receptor signaling pathway

1 reference

8 April 2019

Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

isotype switching to IgG isotypes

1 reference

8 April 2019

Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

B cell cytokine production

1 reference

8 April 2019

Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

response to unfolded protein

1 reference

8 April 2019

The importance of a mobile loop in regulating chaperonin/ co-chaperonin interaction: humans versus Escherichia coli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

positive regulation of T cell mediated immune response to tumor cell

1 reference

8 April 2019

gammadelta T cells lyse autologous and allogenic oesophageal tumours: involvement of heat-shock proteins in the tumour cell lysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

positive regulation of interleukin-6 production

1 reference

8 April 2019

Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

positive regulation of apoptotic process

1 reference

8 April 2019

Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

activation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

8 April 2019

Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

protein import into mitochondrial intermembrane space

TAS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

chaperone-mediated protein folding

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

apoptotic mitochondrial changes

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

positive regulation of interferon-alpha production

1 reference

8 April 2019

Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

positive regulation of interferon-gamma production

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

3 references

26 September 2017

Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

26 September 2017

Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

26 September 2017

Lipopolysaccharide-free heat shock protein 60 activates T cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10809&geneProductId=UniProtKB:P10809

negative regulation of apoptotic process

positive regulation of T cell activation

IMP

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

mitochondrion organization

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

4 references

8 April 2019

Lipopolysaccharide-free heat shock protein 60 activates T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10809

imported from Wikimedia project

Gene Atlas image

PBB GE CD44 204490 s at tn.png
255 × 135; 847 bytes

1 reference

English Wikipedia

has part(s)

Chaperonin Cpn60, conserved site

1 reference