Akt isoforms differentially regulate neutrophil functions (Q30494741)

24 September 2017

Akt isoforms differentially regulate neutrophil functions (English)

1 reference

24 September 2017

Jia Chen

1

1 reference

24 September 2017

Haiyang Tang

2

1 reference

24 September 2017

Nissim Hay

3

1 reference

24 September 2017

Jingsong Xu

4

1 reference

24 September 2017

Richard D Ye

5

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24 September 2017

language of work or name

English

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publication date

23 March 2010

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24 September 2017

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24 September 2017

115

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24 September 2017

21

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24 September 2017

4237-4246

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describes a project that uses

24 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2879106/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Akt1 is critical for acute inflammation and histamine-mediated vascular leakage

28 July 2018

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p47phox, the phagocyte NADPH oxidase/NOX2 organizer: structure, phosphorylation and implication in diseases

28 July 2018

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Insulin-modulated Akt subcellular localization determines Akt isoform-specific signaling

28 July 2018

1 reference

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Identification of formyl peptides from Listeria monocytogenes and Staphylococcus aureus as potent chemoattractants for mouse neutrophils

28 July 2018

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Characterization of a mutation in the Phox homology domain of the NADPH oxidase component p40phox identifies a mechanism for negative regulation of superoxide production

28 July 2018

1 reference

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Physiological roles of PKB/Akt isoforms in development and disease

28 July 2018

1 reference

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Regulation of leukocyte degranulation by cGMP-dependent protein kinase and phosphoinositide 3-kinase: potential roles in phosphorylation of target membrane SNARE complex proteins in rat mast cells

28 July 2018

1 reference

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Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner.

28 July 2018

1 reference

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Regulation of Akt/PKB by phosphatidylinositol 3-kinase-dependent and -independent pathways in B-cell chronic lymphocytic leukemia cells: role of protein kinase C{beta}.

28 July 2018

1 reference

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Life with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies

28 July 2018

1 reference

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Functional distinctions of protein kinase B/Akt isoforms defined by their influence on cell migration

28 July 2018

1 reference

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Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition

28 July 2018

1 reference

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Neutrophil microtubules suppress polarity and enhance directional migration

28 July 2018

1 reference

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Role for Akt3/protein kinase Bgamma in attainment of normal brain size

28 July 2018

1 reference

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Reconstitution of chemotactic peptide-induced nicotinamide adenine dinucleotide phosphate (reduced) oxidase activation in transgenic COS-phox cells

28 July 2018

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Roles of PI3K in Neutrophil Function

28 July 2018

1 reference

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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

28 July 2018

1 reference

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Modulation of p47 PHOX activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase

28 July 2018

1 reference

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Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

28 July 2018

1 reference

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Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

28 July 2018

1 reference

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p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils

28 July 2018

1 reference

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Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

28 July 2018

1 reference

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Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

28 July 2018

1 reference

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Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879106

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha

28 July 2018

1 reference

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Role of translocation in the activation and function of protein kinase B

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879106

Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase

28 July 2018

1 reference

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Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins

28 July 2018

1 reference

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Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879106

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879106

The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879106

Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879106

Protein kinase C betaII regulates Akt phosphorylation on Ser-473 in a cell type- and stimulus-specific fashion.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879106

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879106

Akt Phosphorylates p47phoxand Mediates Respiratory Burst Activity in Human Neutrophils

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879106

Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879106

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879106

Cbl and Akt regulate CXCL8-induced and CXCR1- and CXCR2-mediated chemotaxis

26 November 2018

1 reference

12 December 2020

Activation of p38 in stimulated human neutrophils: phosphorylation of the oxidase component p47phox by p38 and ERK but not by JNK

1 reference

12 December 2020

Opposing Roles for Akt1 and Akt2 in Rac/Pak Signaling and Cell Migration

1 reference

12 December 2020

Functional studies of Akt isoform specificity in skeletal muscle in vivo; maintained insulin sensitivity despite reduced insulin receptor substrate-1 expression

1 reference

12 December 2020

Unequal Contribution of Akt Isoforms in the Double-Negative to Double-Positive Thymocyte Transition

1 reference

12 December 2020

G-Protein-coupled receptors and Fcgamma-receptors mediate activation of Akt/protein kinase B in human phagocytes

1 reference

12 December 2020

10.1182/BLOOD-2009-11-255323

Identifiers

DOI

1 reference

24 September 2017

1 reference

24 September 2017

PubMed publication ID

20332370

1 reference