Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo (Q30499862)

19 October 2017

Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo (English)

1 reference

blood vessel endothelial cell fate specification

19 October 2017

0 references

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0097101

endothelial tip cell fate specification

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0097102

endothelial stalk cell fate specification

1 reference

Gene Ontology release 2020-05-02

1 reference

Stefan Schulte-Merker

8

0 references

author name string

Janna Krueger

1

1 reference

19 October 2017

Dong Liu

2

1 reference

19 October 2017

Katja Scholz

3

1 reference

19 October 2017

Anja Zimmer

4

1 reference

19 October 2017

Yu Shi

5

1 reference

19 October 2017

Christian Klein

6

1 reference

19 October 2017

Arndt Siekmann

7

1 reference

19 October 2017

Melissa Cudmore

9

1 reference

19 October 2017

Asif Ahmed

10

1 reference

19 October 2017

Ferdinand le Noble

11

1 reference

19 October 2017

language of work or name

English

0 references

publication date

1 May 2011

1 reference

19 October 2017

10

1 reference

inferred from page(s)

published in

Development

1 reference

19 October 2017

138

1 reference

19 October 2017

10

1 reference

19 October 2017

2111-2120

1 reference

Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Local guidance of emerging vessel sprouts requires soluble Flt-1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Role and therapeutic potential of VEGF in the nervous system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Ccbe1 is required for embryonic lymphangiogenesis and venous sprouting

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

A genetic screen for vascular mutants in zebrafish reveals dynamic roles for Vegf/Plcg1 signaling during artery development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Angiogenesis: a team effort coordinated by notch.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Zebrafish VEGF receptors: a guideline to nomenclature

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Foxn4 directly regulates tbx2b expression and atrioventricular canal formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Gateway compatible vectors for analysis of gene function in the zebrafish.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Regulation of vascular morphogenesis by Notch signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Early endocardial morphogenesis requires Scl/Tal1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Corneal avascularity is due to soluble VEGF receptor-1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Lymphangiogenesis in development and human disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

The vascular endothelial growth factor (VEGF) receptor Flt-1 (VEGFR-1) modulates Flk-1 (VEGFR-2) signaling during blood vessel formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Slow degeneration of zebrafish Rohon-Beard neurons during programmed cell death

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

The biology of VEGF and its receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

In vivo imaging of embryonic vascular development using transgenic zebrafish

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Analysis of upstream elements in the HuC promoter leads to the establishment of transgenic zebrafish with fluorescent neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

A novel human-specific soluble vascular endothelial growth factor receptor 1: cell-type-specific splicing and implications to vascular endothelial growth factor homeostasis and preeclampsia

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

VEGF-PLCgamma1 pathway controls cardiac contractility in the embryonic heart

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

The pu.1 promoter drives myeloid gene expression in zebrafish.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Sensory nerves determine the pattern of arterial differentiation and blood vessel branching in the skin

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082310

Whole-mount in situ hybridizations on zebrafish embryos using a mixture of digoxigenin- and fluorescein-labelled probes

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21521739

12 December 2020

inferred from PubMed ID database lookup

Angiogenic network formation in the developing vertebrate trunk

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21521739

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1242/DEV.063933

1 reference

release_4o5mx3s3gzappgwm4ck7vm4yz4

19 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4o5mx3s3gzappgwm4ck7vm4yz4

24 November 2022

mapped directly with Wikidata item

1 reference

19 October 2017

1 reference