Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations. (Q30826748)

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26 March 2020

title

Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations (English)

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26 March 2020

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4

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26 March 2020

Giulia Palermo

1

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26 March 2020

Yinglong Miao

2

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26 March 2020

author name string

Ross C Walker

3

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26 March 2020

J Andrew McCammon

5

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26 March 2020

publication date

9 September 2016

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26 March 2020

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26 March 2020

volume

2

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26 March 2020

issue

10

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26 March 2020

page(s)

756-763

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Detecting Allosteric Networks Using Molecular Dynamics Simulation

26 March 2020

cites work

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Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

21 June 2018

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Molecular Simulations Highlight the Role of Metals in Catalysis and Inhibition of Type II Topoisomerase

21 June 2018

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Conformational control of DNA target cleavage by CRISPR-Cas9.

21 June 2018

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STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

21 June 2018

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Engineered CRISPR-Cas9 nucleases with altered PAM specificities

21 June 2018

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The structural biology of CRISPR-Cas systems

21 June 2018

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Rational design of a split-Cas9 enzyme complex

21 June 2018

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Catalytic metal ions and enzymatic processing of DNA and RNA.

21 June 2018

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Genome editing. The new frontier of genome engineering with CRISPR-Cas9

21 June 2018

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Programmable RNA recognition and cleavage by CRISPR/Cas9.

21 June 2018

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Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

21 June 2018

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Development and applications of CRISPR-Cas9 for genome engineering

21 June 2018

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Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

21 June 2018

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

21 June 2018

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DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

21 June 2018

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

21 June 2018

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Refinement of the Cornell et al. Nucleic Acids Force Field Based on Reference Quantum Chemical Calculations of Glycosidic Torsion Profiles

21 June 2018

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Phosphodiester cleavage in ribonuclease H occurs via an associative two-metal-aided catalytic mechanism.

21 June 2018

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Refinement of the AMBER force field for nucleic acids: improving the description of alpha/gamma conformers

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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25 November 2018

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27800559

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ACSCENTSCI.6B00218

1 reference

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26 March 2020

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26 March 2020

PubMed publication ID

27800559

1 reference