Overexpression of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability (Q30922231)

11 September 2017

1 reference

14 July 2021

Overexpression of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability (English)

1 reference

DNA recombination/repair protein Rad51

11 September 2017

1 reference

14 September 2019

1 reference

28 September 2019

1 reference

inferred from abstract

1 reference

8 February 2021

1 reference

14 July 2021

genetic recombination

1 reference

PubMed publication ID

19942681

author name string

David Schild

series ordinal

1

1 reference

11 September 2017

Claudia Wiese

series ordinal

2

1 reference

11 September 2017

language of work or name

English

0 references

publication date

26 November 2009

1 reference

11 September 2017

1 March 2010

9 references

3 April 2019

20 June 2019

30 June 2019

14 September 2019

28 September 2019

11 December 2019

13 December 2019

8 February 2021

14 July 2021

Nucleic Acids Research

10 references

11 September 2017

3 April 2019

20 June 2019

30 June 2019

14 September 2019

28 September 2019

11 December 2019

13 December 2019

8 February 2021

14 July 2021

38

1 reference

11 September 2017

4

1 reference

11 September 2017

1061-1070

1 reference

Creative Commons Attribution-NonCommercial

11 September 2017

9 references

3 April 2019

20 June 2019

30 June 2019

14 September 2019

28 September 2019

11 December 2019

13 December 2019

8 February 2021

14 July 2021

on focus list of Wikimedia project

ScienceSource

0 references

cites work

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The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange

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Human replication protein A-Rad52-single-stranded DNA complex: stoichiometry and evidence for strand transfer regulation by phosphorylation

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DNA-binding Domain within the Brh2 N Terminus Is the Primary Interaction Site for Association with DNA.

21 June 2018

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Targeting homologous recombination using imatinib results in enhanced tumor cell chemosensitivity and radiosensitivity

21 June 2018

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Recovery of deficient homologous recombination in Brca2-depleted mouse cells by wild-type Rad51 expression

21 June 2018

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Rad51 overexpression rescues radiation resistance in BRCA2-defective cancer cells

21 June 2018

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Distinct RAD51 associations with RAD52 and BCCIP in response to DNA damage and replication stress

21 June 2018

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Mechanism of eukaryotic homologous recombination

21 June 2018

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Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability.

21 June 2018

1 reference

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The consequences of Rad51 overexpression for normal and tumor cells

21 June 2018

1 reference

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RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies

21 June 2018

1 reference

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Promotion of homologous recombination and genomic stability by RAD51AP1 via RAD51 recombinase enhancement

21 June 2018

1 reference

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RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors

21 June 2018

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The genomic landscapes of human breast and colorectal cancers

21 June 2018

1 reference

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Activation of BRCA1/BRCA2-associated helicase BACH1 is required for timely progression through S phase

21 June 2018

1 reference

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Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation

21 June 2018

1 reference

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

21 June 2018

1 reference

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Mechanism of homologous recombination: mediators and helicases take on regulatory functions

21 June 2018

1 reference

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Pir51, a Rad51-interacting protein with high expression in aggressive lymphoma, controls mitomycin C sensitivity and prevents chromosomal breaks

21 June 2018

1 reference

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Links between DNA double strand break repair and breast cancer: accumulating evidence from both familial and nonfamilial cases.

21 June 2018

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Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

21 June 2018

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Double bolt regulation of Rad51 by p53: a role for transcriptional repression.

21 June 2018

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Sws1 is a conserved regulator of homologous recombination in eukaryotic cells

21 June 2018

1 reference

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Chinese hamster cell mutant, V-C8, a model for analysis of Brca2 function

21 June 2018

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p53 in recombination and repair

21 June 2018

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Repression of mutagenesis by Rad51D-mediated homologous recombination

21 June 2018

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Characterisation of the promoter region of the human DNA-repair gene Rad51

21 June 2018

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Interplay between human DNA repair proteins at a unique double-strand break in vivo

21 June 2018

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p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene

21 June 2018

1 reference

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DSS1 is required for the stability of BRCA2

21 June 2018

1 reference

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Differential and collaborative actions of Rad51 paralog proteins in cellular response to DNA damage

21 June 2018

1 reference

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Extensive chromosomal instability in Rad51d-deficient mouse cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

RAD51 localization and activation following DNA damage

21 June 2018

1 reference

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Genes encoding Pir51, Beclin 1, RbAp48 and aldolase b are up or down-regulated in human primary hepatocellular carcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair

21 June 2018

1 reference

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Gleevec-mediated inhibition of Rad51 expression and enhancement of tumor cell radiosensitivity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Rad51 recombinase and recombination mediators

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cells

21 June 2018

1 reference

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BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance

21 June 2018

1 reference

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Effects of HsRad51 overexpression on cell proliferation, cell cycle progression, and apoptosis

21 June 2018

1 reference

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Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancer

21 June 2018

1 reference

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Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs

21 June 2018

1 reference

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The Rad51 paralog Rad51B promotes homologous recombinational repair

21 June 2018

1 reference

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BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: evidence and implications

21 June 2018

1 reference

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21 June 2018

The Hallmarks of Cancer

1 reference

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XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Interaction of p53 with the human Rad51 protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Functional Differences and Interactions among the Putative RecA Homologs Rad51, Rad55, and Rad57

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Suppression of a new allele of the yeast RAD52 gene by overexpression of RAD51, mutations in srs2 and ccr4, or mating-type heterozygosity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Cancer. Complicated supercomplexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

RAD51AP1 is a structure-specific DNA binding protein that stimulates joint molecule formation during RAD51-mediated homologous recombination

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Ten genes for inherited breast cancer.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Microsatellite instability in colorectal cancer

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

BRCA1 DNA-binding activity is stimulated by BARD1.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Xrcc3 is recruited to DNA double strand breaks early and independent of Rad51.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831301

The Yin and Yang of treating BRCA-deficient tumors

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19942681

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKP1063

1 reference

11 September 2017

1 reference

11 September 2017

PubMed publication ID

19942681

1 reference