Statistical and biological gene-lifestyle interactions of MC4R and FTO with diet and physical activity on obesity: new effects on alcohol consumption (Q31110205)

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English	Statistical and biological gene-lifestyle interactions of MC4R and FTO with diet and physical activity on obesity: new effects on alcohol consumption	scientific article

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scholarly article

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Europe PubMed Central

14 August 2017

Statistical and biological gene-lifestyle interactions of MC4R and FTO with diet and physical activity on obesity: new effects on alcohol consumption (English)

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Europe PubMed Central

14 August 2017

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alcohol consumption

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José María Ordovás

18

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Europe PubMed Central

28 June 2017

object named as

Amelia Martí

16

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Rosa Lamuela-Raventos

object named as

Rosa Lamuela-Raventos

11

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object named as

Xavier Pintó

14

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object named as

Emilio Ros

15

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Miguel Ángel Martínez-González

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Miguel Ángel Martínez-González

7

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Jordi Salas-Salvadó

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Jordi Salas-Salvadó

6

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Lluís Serra Majem

object named as

Lluís Serra-Majem

10

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Paula Carrasco

5

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Carolina Ortega-Azorín

2

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Carolina Ortega-Azorín

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Europe PubMed Central

14 August 2017

3

object named as

Jose V Sorlí

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Europe PubMed Central

14 August 2017

17

object named as

Oscar Coltell

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Europe PubMed Central

14 August 2017

8

object named as

Fernando Arós

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Europe PubMed Central

14 August 2017

9

object named as

José Lapetra

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Europe PubMed Central

14 August 2017

Enrique Gómez-Gracia

12

object named as

Enrique Gómez-Gracia

1 reference

Europe PubMed Central

14 August 2017

Miquel Àngel Fiol

13

object named as

Miquel Fiol

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Europe PubMed Central

14 August 2017

Dolores Corella Piquer

1

object named as

Dolores Corella

1 reference

Europe PubMed Central

14 August 2017

author name string

M Isabel Covas

4

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14 August 2017

Ramon Estruch

19

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Europe PubMed Central

14 August 2017

language of work or name

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publication date

21 December 2012

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Europe PubMed Central

14 August 2017

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Europe PubMed Central

14 August 2017

7

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Europe PubMed Central

14 August 2017

e52344

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Europe PubMed Central

14 August 2017

12

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Europe PubMed Central

14 August 2017

copyright license

Creative Commons Attribution 4.0 International

21 December 2012

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April 2022 Public Data File from Crossref

copyright status

0 references

The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Association between FTO variant and change in body weight and its interaction with dietary factors: the DiOGenes study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

A high intake of saturated fatty acids strengthens the association between the fat mass and obesity-associated gene and BMI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Associations of FTO and MC4R Variants with Obesity Traits in Indians and the Role of Rural/Urban Environment as a Possible Effect Modifier

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

FTO gene polymorphisms and obesity risk: a meta-analysis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Influence of common variants in FTO and near INSIG2 and MC4R on growth curves for adiposity in African- and European-American youth

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

FTO, type 2 diabetes, and weight gain throughout adult life: a meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Assessment of voluntary ethanol consumption and the effects of a melanocortin (MC) receptor agonist on ethanol intake in mutant C57BL/6J mice lacking the MC-4 receptor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

The genetic epidemiology of melanocortin 4 receptor variants.

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28 July 2018

Education modulates the association of the FTO rs9939609 polymorphism with body mass index and obesity risk in the Mediterranean population.

1 reference

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28 July 2018

The meaning of interaction

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28 July 2018

Statistical interaction in human genetics: how should we model it if we are looking for biological interaction?

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28 July 2018

Overexpression of Fto leads to increased food intake and results in obesity

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28 July 2018

FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Nutrigenomics in cardiovascular medicine

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28 July 2018

Influence of common variants near INSIG2, in FTO, and near MC4R genes on overweight and the metabolic profile in adolescence: the TRAILS (TRacking Adolescents' Individual Lives Survey) Study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Evidence that multiple genetic variants of MC4R play a functional role in the regulation of energy expenditure and appetite in Hispanic children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Life course variations in the associations between FTO and MC4R gene variants and body size

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Fat and carbohydrate intake modify the association between genetic variation in the FTO genotype and obesity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

An obesity-associated FTO gene variant and increased energy intake in children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

The fat mass- and obesity-associated locus and dietary intake in children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Physical activity and the association of common FTO gene variants with body mass index and obesity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change and diabetes risk in women

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Gene-environment interactions for complex traits: definitions, methodological requirements and challenges

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Common variants near MC4R are associated with fat mass, weight and risk of obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

28 July 2018

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene

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28 July 2018

Sample size determination for studies of gene-environment interaction

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28 July 2018

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052344

21 January 2018

Common variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 show evidence of association with adult obesity in the Greek population

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052344

21 January 2018

Combined effects of MC4R and FTO common genetic variants on obesity in European general populations.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052344

21 January 2018

Combined effects of FTO rs9939609 and MC4R rs17782313 on obesity and BMI in Chinese Han populations

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052344

21 January 2018

Characterization of the hyperphagic response to dietary fat in the MC4R knockout mouse.

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21 January 2018

Variation in the FTO gene influences food intake but not energy expenditure

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052344

21 January 2018

FTO genotype is associated with body mass index after the age of seven years but not with energy intake or leisure-time physical activity

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052344

21 January 2018

Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052344

21 January 2018

Influence of physical inactivity on associations between single nucleotide polymorphisms and genetic predisposition to childhood obesity.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052344

21 January 2018

High dietary saturated fat intake accentuates obesity risk associated with the fat mass and obesity-associated gene in adults

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052344

21 January 2018

Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial.

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21 January 2018

Cohort profile: design and methods of the PREDIMED study

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21 January 2018

A short screener is valid for assessing Mediterranean diet adherence among older Spanish men and women.

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21 January 2018

Prevalence of pathogenetic MC4R mutations in Italian children with early onset obesity, tall stature and familial history of obesity

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21 January 2018

Obesity due to melanocortin 4 receptor (MC4R) deficiency is associated with increased linear growth and final height, fasting hyperinsulinemia, and incompletely suppressed growth hormone secretion.

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21 January 2018

Effects of melanocortin receptor activation and blockade on ethanol intake: a possible role for the melanocortin-4 receptor

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21 January 2018

Effect of the melanocortin receptor stimulation or inhibition on ethanol intake in alcohol-preferring rats

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21 January 2018

Inverse association of the obesity predisposing FTO rs9939609 genotype with alcohol consumption and risk for alcohol dependence.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052344

21 January 2018

Common genetic variants at the MC4R locus are associated with obesity, but not with dietary energy intake or colorectal cancer in the Scottish population

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21 January 2018

Interaction: A word with two meanings creates confusion

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21 January 2018

Validation of the Minnesota Leisure Time Physical Activity Questionnaire in Spanish Men

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21 January 2018

Validation of the Minnesota Leisure Time Physical Activity Questionnaire in Spanish Women

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21 January 2018

Relative validity of a semi-quantitative food-frequency questionnaire in an elderly Mediterranean population of Spain

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21 January 2018

Associations of Variants inFTOand NearMC4RWith Obesity Traits in South Asian Indians

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25 November 2018

Interactions between the FTO rs9939609 polymorphism, body mass index, and lifestyle-related factors on metabolic syndrome risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

25 November 2018

Association of the fat mass and obesity-associated (FTO) gene variant (rs9939609) with dietary intake in the Finnish Diabetes Prevention Study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

25 November 2018

A 3-year intervention with a Mediterranean diet modified the association between the rs9939609 gene variant in FTO and body weight changes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

25 November 2018

Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528751

25 November 2018

Diagnosis and classification of diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23284998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melanocortin activity in the amygdala influences alcohol intake

1 reference

https://pubmed.ncbi.nlm.nih.gov/23284998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alcohol and heart disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23284998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

β2-Adrenergic Receptor Thr164Ile Polymorphism, Obesity, and Diabetes: Comparison with FTO, MC4R, and TMEM18 Polymorphisms in More Than 64,000 Individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/23284998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Variant in the Fat Mass and Obesity-Associated Gene (FTO) and Variants near the Melanocortin-4 Receptor Gene (MC4R) Do Not Influence Dietary Intake

1 reference

https://pubmed.ncbi.nlm.nih.gov/23284998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0052344

1 reference

Europe PubMed Central

14 August 2017

2012PLoSO...752344C

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1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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